BAY-320
- CAS No.
- 1445830-50-1
- Chemical Name:
- BAY-320
- Synonyms
- BAY-320;BAY320,BAY 320;2-(5-Cyclopropyl-1-(4-ethoxy-2,6-difluorobenzyl)-4-methyl-1H-pyrazol-3-yl)-5-methoxy-N-(pyridin-4-yl)pyrimidin-4-amine;4-Pyrimidinamine, 2-[5-cyclopropyl-1-[(4-ethoxy-2,6-difluorophenyl)methyl]-4-methyl-1H-pyrazol-3-yl]-5-methoxy-N-4-pyridinyl-
- CBNumber:
- CB34667608
- Molecular Formula:
- C26H26F2N6O2
- Molecular Weight:
- 492.52
- MDL Number:
- MFCD31657346
- MOL File:
- 1445830-50-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
BAY-320 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | VHC83050 | BAY-320 | 1445830-50-1 | 5mg | $1280.7 | 2026-06-05 | Buy |
| Biosynth | VHC83050 | BAY-320 | 1445830-50-1 | 10mg | $1781.9 | 2026-06-05 | Buy |
| Biosynth | VHC83050 | BAY-320 | 1445830-50-1 | 25mg | $3341.25 | 2026-06-05 | Buy |
| Biosynth | VHC83050 | BAY-320 | 1445830-50-1 | 50mg | $5346 | 2026-06-05 | Buy |
| ChemScene | CS-0023458 | BAY-320 99.74% | 1445830-50-1 | 5mg | $520 | 2026-06-04 | Buy |
BAY-320 Chemical Properties, Uses, Production
Uses
BAY-320 is a selective and ATP-competitive Bub1 inhibitor that inhibits the kinase activity of Bub1 with an IC50 of 680 nM. BAY-320 inhibits endogenous Bub1-mediated Sgo1 localization. BAY-320 affects cellular mitotic chromosome arrangement and spindle assembly. BAY-320 inhibits cell proliferation. BAY-320 can be used in the study of cancer[1].
References
[1] Amalina I, et al. Inhibitors of the Bub1 spindle assembly checkpoint kinase: synthesis of BAY-320 and comparison with 2OH-BNPP1. R Soc Open Sci. 2021 Dec 15;8(12):210854. DOI:10.1098/rsos.210854
[2] Baron AP, et al. Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524. Elife. 2016 Feb 17;5. pii: e12187. DOI:10.7554/eLife.12187
BAY-320 Preparation Products And Raw materials
Raw materials
Preparation Products
BAY-320 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28150 | 68 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| Kaifeng Mingren Pharmaceutical Co.,LTD | 0371-65741762 | sales@hasunny.com | China | 2377 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5985 | 58 |
| Shandong Dayou Pharmaceutical Research and Development Co., Ltd. | hanfangpharma@126.com 15165037910 | hanfangpharma@126.com | China | 25800 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd | 025-5885952 15955137747 | sales@aikonchem.com | China | 8012 | 58 |
View Latest Price from BAY-320 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-22 | BAY-320
1445830-50-1
|
$1670.00-2800.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2026-05-21 | BAY-320
1445830-50-1
|
$1670.00-2800.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-07-22 | BAY-320
1445830-50-1
|
$1650.00-3310.00 | 10g | TargetMol Chemicals Inc. |
