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METHYL 4-(4-AMINOPHENYL)BUTANOATE

METHYL 4-(4-AMINOPHENYL)BUTANOATE structure

CAS No.: 20637-09-6

Chemical Name:: METHYL 4-(4-AMINOPHENYL)BUTANOATE

Synonyms: Einecs 243-933-0;Methyl 4-aminobenzenebutanoate;Methyl 4-(4-aminophenyl)butyrate;METHYL 4-(4-AMINOPHENYL)BUTYARTE;Methyl 4-(4-Aminopheny)Butanoate;METHYL 4-(4-AMINOPHENYL)BUTANOATE;4-aminophenylbutyricacidmethylester;4-(4-Aminophenyl)butyricacidmethylester;4-Aminobenzenebutyric acid methyl ester;p-Aminobenzenebutanoic acid methyl ester

CBNumber:: CB3470831

Molecular Formula:: C11H15NO2

Molecular Weight:: 193.24

MDL Number:: MFCD07366753

MOL File:: 20637-09-6.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:46

Product description	Number	Pack Size	Price
Methyl4-(4-Aminophenyl)butanoate	M328745	100mg	$45
Methyl4-(4-Aminophenyl)butanoate	M328745	500mg	$105
Methyl4-(4-Aminophenyl)butanoate	M328745	1g	$165
4-(4-Aminophenyl)butyricacidmethylester	R798	5g	$370
METHYL-4-(4-AMINOPHENYL)BUTANOATE 96.00%	CHM0290531	5G	$1530.38
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METHYL 4-(4-AMINOPHENYL)BUTANOATE Properties

Melting point	42 °C(Solv: ligroine (8032-32-4))
Boiling point	323.9±25.0 °C(Predicted)
Density	1.088±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	4.83±0.10(Predicted)
Appearance	Brown to dark brown <42°C Solid,>42°C Liquid
InChI	InChI=1S/C11H15NO2/c1-14-11(13)4-2-3-9-5-7-10(12)8-6-9/h5-8H,2-4,12H2,1H3
InChIKey	CLKHQWJXESOLCJ-UHFFFAOYSA-N
SMILES	C1(CCCC(OC)=O)=CC=C(N)C=C1
NIST Chemistry Reference	4-(4-Aminophenyl)butanoic acid methyl ester(20637-09-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
HS Code	2922498590

METHYL 4-(4-AMINOPHENYL)BUTANOATE price More Price(19)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	M328745	Methyl4-(4-Aminophenyl)butanoate	20637-09-6	100mg	$45	2021-12-16	Buy
TRC	M328745	Methyl4-(4-Aminophenyl)butanoate	20637-09-6	500mg	$105	2021-12-16	Buy
TRC	M328745	Methyl4-(4-Aminophenyl)butanoate	20637-09-6	1g	$165	2021-12-16	Buy
AK Scientific	R798	4-(4-Aminophenyl)butyricacidmethylester	20637-09-6	5g	$370	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0290531	METHYL-4-(4-AMINOPHENYL)BUTANOATE 96.00%	20637-09-6	5G	$1530.38	2021-12-16	Buy

Product number	Packaging	Price	Buy
M328745	100mg	$45	Buy
M328745	500mg	$105	Buy
M328745	1g	$165	Buy
R798	5g	$370	Buy
CHM0290531	5G	$1530.38	Buy

METHYL 4-(4-AMINOPHENYL)BUTANOATE Chemical Properties,Uses,Production

Uses

Methyl 4-(4-Aminophenyl)butanoate is used in the synthesis of derivative of chlorambucil, a selective anti-cancer drug toward chondrosarcoma that would concentrate in this malignant cartilaginous tissue.

Synthesis

4-Nitrobenzenebutanoic acid methyl ester

20637-02-9

20637-09-6

b) Synthesis of methyl 4-(4-aminophenyl)butyrate Methyl 4-(4-nitrophenyl)butyrate (3.05 g, 13.67 mmol) and Pd/C catalyst (1.0 g, 10% Pd, activated carbon carrier, 1.09 mmol) were suspended in methanol (40 mL). The reaction mixture was stirred under hydrogen atmosphere (balloon pressure) for 1 hour. After completion of the reaction, the reaction mixture was filtered through a diatomaceous earth pad (washed with ethyl acetate). The filtrate was concentrated under reduced pressure to give 2.33 g of methyl 4-(4-aminophenyl)butyrate (brown solid, yield: 88%). The product did not require further purification and could be used directly in the next step of the reaction. 1H NMR (CDCl3, 250MHz) δppm: 6.96 (d, J=8.5Hz, 2H), 6.63 (d, J=8.2Hz, 2H), 3.66 (s, 3H), 2.55 (t, J=7.6Hz, 2H), 2.31 (t, J=7.7Hz, 2H), 1.90 (q, J=7.6Hz, 2H).

References

[1] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 17, p. 6463 - 6480
[2] Patent: WO2009/80722, 2009, A2. Location in patent: Page/Page column 52
[3] Journal of Pharmaceutical Sciences, 1988, vol. 77, # 2, p. 185 - 187
[4] Journal of the Chemical Society, 1953, p. 2386,2387
[5] Journal of Medicinal Chemistry, 1990, vol. 33, # 11, p. 3014 - 3019

METHYL 4-(4-AMINOPHENYL)BUTANOATE synthesis

Synthesis of METHYL 4-(4-AMINOPHENYL)BUTANOATE from Methanol and 4-(4-Aminophenyl)butyric acid

METHYL 4-(4-AMINOPHENYL)BUTANOATE Preparation Products And Raw materials

Raw materials

Hydrogen chloride methanol solution 4-(4-Aminophenyl)butyric acid Benzenebutanoic acid, 4-amino-γ-oxo-, methyl ester Benzenebutanoic acid, 4-nitro-γ-oxo-, methyl ester 4-(2-NITRO-PHENYL)-BUTYRIC ACID

4-(2-aminophenyl)butanoic acid methyl ester 4-Nitrobenzenebutanoic acid methyl ester 3-(4-ACETYLAMINOBENZOYL)PROPANOIC ACID 4-(4-Nitrophenyl)butyric acid 4-Vinylanilin

Methanol Acetanilide (TRIMETHYLSILYL)DIAZOMETHANE Methyl thioglycolate 4-Phenylbutyric acid

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Preparation Products

METHYL 4-(4-AMINOPHENYL)BUTANOATE Suppliers

Global( 72)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29734	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13456	58
Chembon Pharmaceutical Co., Ltd.	+86-28-8425-2981		CHINA	722	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29799	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15142	58
Henan Alfa Chemical Co., Ltd	+8615838112936	alfa10@alfachem.cn	China	12931	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	24727	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Chembon Pharmaceutical Co., Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
AFINE CHEMICALS LIMITED	58
Henan Alfa Chemical Co., Ltd	58
HANGZHOU LEAP CHEM CO., LTD.	58

View Lastest Price from METHYL 4-(4-AMINOPHENYL)BUTANOATE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-13	METHYL 4-(4-AMINOPHENYL)BUTANOATE 20637-09-6	US $6.68 / KG	1KG	97%-99%	1kg-1000kg	Career Henan Chemical Co

METHYL 4-(4-AMINOPHENYL)BUTANOATE
20637-09-6
US $6.68 / KG
97%-99%
Career Henan Chemical Co

METHYL 4-(4-AMINOPHENYL)BUTANOATE Spectrum

METHYL 4-(4-AMINOPHENYL)BUTANOATE(20637-09-6)¹HNMR

20637-09-6(METHYL 4-(4-AMINOPHENYL)BUTANOATE)Related Search:

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4-(4-NITRO-PHENYL)-3-OXO-BUTYRIC ACID METHYL ESTER Methylene dithiocyanate 4-(4-NITRO-PHENYL)-3-OXO-BUTYRIC ACID ETHYL ESTER ETHYL 4-(4-AMINOPHENYL)BUTANOATE

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4-(4-Aminophenyl)butyricacidmethylester METHYL 4-(4-AMINOPHENYL)BUTANOATE METHYL 4-(4-AMINOPHENYL)BUTYARTE 4-aminophenylbutyricacidmethylester Benzenebutanoic acid, 4-amino-, methyl ester Butyric acid, 4-(p-aminophenyl)-, methyl ester Methyl 4-(4-aminophenyl)butyrate Methyl 4-aminobenzenebutanoate 4-(4-Aminophenyl)butanoic acid methyl ester 4-Aminobenzenebutyric acid methyl ester p-Aminobenzenebutanoic acid methyl ester Methyl 4-(4-Aminopheny)Butanoate Einecs 243-933-0 20637-09-6