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PF-06748962

PF-06748962 Structure
PF-06748962 structure
CAS No.
1952261-87-8
Chemical Name:
PF-06748962
Synonyms
PF-06748962;PF-06748962 >=98% (HPLC);2(1H)-Pyridinone, 3-[(3R)-3-methyl-2-oxo-3-piperidinyl]-6-(5-methyl-3-quinolinyl)-
CBNumber:
CB34742404
Molecular Formula:
C21H21N3O2
Molecular Weight:
347.41
MDL Number:
MOL File:
1952261-87-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-11 19:39:08
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PF-06748962 Properties

storage temp. room temp
solubility DMSO: 20mg/mL, clear
form powder
color white to beige
optical activity [α]/D -880 to -920°, c = 0.5 in chloroform-d
SMILES CC1=CC=CC2=NC=C(C3=CC=C([C@]4(C)C(NCCC4)=O)C(N3)=O)C=C21
UNSPSC Code 12352202
NACRES NA.77

SAFETY

Risk and Safety Statements

WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

PF-06748962 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PZ0350 PF-06748962 ≥98% (HPLC) 1952261-87-8 5mg $83.7 2024-03-01 Buy
Sigma-Aldrich PZ0350 PF-06748962 ≥98% (HPLC) 1952261-87-8 25mg $338 2024-03-01 Buy
aablocks AA023NT5 PF-06748962 1952261-87-8 50mg $799 2026-06-01 Buy
Product number Packaging Price Buy
PZ0350 5mg $83.7 Buy
PZ0350 25mg $338 Buy
AA023NT5 50mg $799 Buy

PF-06748962 Chemical Properties, Uses, Production

Uses

EP3 antagonist 2 (Compound Exp 1) is a potent and selective EP3 receptor antagonist. EP3 antagonist 2 has a strong binding affinity for the human EP3 receptor (Ki: 3.3 nM) and significant antagonistic activity (IC50: 30.8 nM, determined by cellular cAMP levels)[1].

Biological Activity

PF-06748962 is a potent and selective lactam-based prostaglandin EP3 receptor antagonist.

References

[1] Kevin Bahnck, et al. Antagonists of prostaglandin ep3 receptor. US20160176851A1. 2016-06-23.

PF-06748962 Preparation Products And Raw materials

Raw materials

Preparation Products

PF-06748962 Suppliers

Global Suppliers ( 8)
Supplier Tel Email Country ProdList Advantage
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4773 55
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1246 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
Guangzhou Isun Pharmaceutical Co., Ltd 55
Energy Chemical 58
Beijing Biocreative Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from PF-06748962 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PF-06748962 pictures 2026-05-11 PF-06748962
1952261-87-8
 $1820.00-3100.00 10g TargetMol Chemicals Inc.
  • PF-06748962 pictures
  • PF-06748962
    1952261-87-8
  • $1820.00-3100.00
  • TargetMol Chemicals Inc.

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PF-06748962 2(1H)-Pyridinone, 3-[(3R)-3-methyl-2-oxo-3-piperidinyl]-6-(5-methyl-3-quinolinyl)- PF-06748962 >=98% (HPLC) 1952261-87-8