4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE
- CAS No.
- 698-29-3
- Chemical Name:
- 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE
- Synonyms
- NSC 459;Pynitrile;BUTTPARK 27\08-63;5-Cyano-4-aMino-2-MethylpyriMidine;4-AMINO-5-CYANO-2-METHYLPYRIMIDINE;2-methyl-4-amino-5-cyanopyrimidine;2-methyl-4-aminopyrimidine-5-nitrile;4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE;2-Methyl-4-aminopyrimidine-5-carbonitrile;5-Pyrimidinecarbonitrile, 4-amino-2-methyl-
- CBNumber:
- CB3477966
- Molecular Formula:
- C6H6N4
- Molecular Weight:
- 134.14
- MDL Number:
- MFCD00084875
- MOL File:
- 698-29-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Amino-5-cyano-2-methylpyrimidine | A1376-65 | 1g | $375 |
| 4-Amino-5-cyano-2-methylpyrimidine | TRC-A603517-5G | 5g | $479 |
| 4-Amino-5-cyano-2-methylpyrimidine | TRC-A603517-2G | 2g | $237 |
| 4-Amino-5-cyano-2-methylpyrimidine | TRC-A603517-1G | 1g | $129 |
| 4-Amino-2-methylpyrimidine-5-carbonitrile 97% | AS47197 | 1g | $28 |
| More product size | |||
| Melting point | 249 °C |
|---|---|
| Boiling point | 315.6±27.0 °C(Predicted) |
| Density | 1.27±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | DMSO, Ethanol, Methanol |
| pka | 3.00±0.10(Predicted) |
| form | Powder |
| color | Pale yellow |
| Water Solubility | Slightly soluble in water (6.4 g/L at 25°C). Soluble in dimethyl sulfoxide, ethanol and methanol. |
| InChI | InChI=1S/C6H6N4/c1-4-9-3-5(2-7)6(8)10-4/h3H,1H3,(H2,8,9,10) |
| InChIKey | YBPNIILOUYAGIF-UHFFFAOYSA-N |
| SMILES | C1(C)=NC=C(C#N)C(N)=N1 |
| CAS DataBase Reference | 698-29-3(CAS DataBase Reference) |
| FDA UNII | EH6ED3UPV9 |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H312-H315-H319-H332-H335 | |||||||||
| Precautionary statements | P261-P280-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 22-37/38-41 | |||||||||
| Safety Statements | 26-39 | |||||||||
| WGK Germany | WGK 1 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| HS Code | 2933599590 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
|||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE price More Price(65)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | A1376-65 | 4-Amino-5-cyano-2-methylpyrimidine | 698-29-3 | 1g | $375 | 2026-06-03 | Buy |
| TRC | TRC-A603517-5G | 4-Amino-5-cyano-2-methylpyrimidine | 698-29-3 | 5g | $479 | 2026-06-03 | Buy |
| TRC | TRC-A603517-2G | 4-Amino-5-cyano-2-methylpyrimidine | 698-29-3 | 2g | $237 | 2026-06-03 | Buy |
| TRC | TRC-A603517-1G | 4-Amino-5-cyano-2-methylpyrimidine | 698-29-3 | 1g | $129 | 2026-06-03 | Buy |
| Activate Scientific | AS47197 | 4-Amino-2-methylpyrimidine-5-carbonitrile 97% | 698-29-3 | 1g | $28 | 2026-06-04 | Buy |
4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE Chemical Properties,Uses,Production
Chemical Properties
Pale-Yellow Crystalline Solid
Uses
4-Amino-5-cyano-2-methylpyrimidine is used as a pharmaceutical intermediate.
Synthesis
To a clean 20L reaction flask, add 5kg of water, 5kg of ethanol and mix well. Take solid sodium hydroxide 1.8kg, add to the system and stir for 30min. until completely dissolved. Cool down the ice bath to below 25 degrees Celsius, add 3.2kg of acetamidine hydrochloride, basically no exothermic, white turbid liquid. After adding, stirring for 10min. dropwise addition of ethanol solution of dicyanoacetate, dropwise initial exothermic, insulation below 30 degrees Celsius, the back of the basic non-exothermic, can accelerate the acceleration of the drop. Dropping finished, warming to 65-70 reaction 1.5h. reaction solution while hot slowly poured into 10kg of ice water, stirring for 20min. treatment of liquid centrifuge centrifugation, get 4.6kg of wet product. 70-75 blast drying, to constant weight. Obtained white solid 3.6kg, liquid phase 98.2%, yield 85.7%.




4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou uniringchem Co., Ltd. | +undefined13585446801 | sales@uniringchem.com | China | 69 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14026 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| ShanghaiFineBiotechCoLtd | +8618717800556 18717800556 | sales@finebioetch.com | CHINA | 318 | 58 |
| KARMEL TECHNOLOGY (HK) CO.,LIMITED | +8618795957998 | karmelhk@126.com | CHINA | 2886 | 58 |
| Dideu Industries Group Limited | +86-86-15536356810 +8617392712697 | 1022@dideu.com | China | 29095 | 58 |
View Lastest Price from 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-30 | 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE
698-29-3
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
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2025-11-18 | 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE
698-29-3
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
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2019-12-20 | 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE
698-29-3
|
$1.00 | 1KG | 97-99% | 1000KGS | Career Henan Chemical Co |
-

- 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE
698-29-3
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-

- 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE
698-29-3
- $1.10
- 99.00%
- Dideu Industries Group Limited
-

- 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE
698-29-3
- $1.00
- 97-99%
- Career Henan Chemical Co
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