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4-Amino-2-methylpyrimidine-5-carbonitrile

4-Amino-2-methylpyrimidine-5-carbonitrile Structure
4-Amino-2-methylpyrimidine-5-carbonitrile structure
CAS No.
698-29-3
Chemical Name:
4-Amino-2-methylpyrimidine-5-carbonitrile
Synonyms
NSC 459;Pynitrile;BUTTPARK 27\08-63;4-AMINO-5-CYANO-2-METHYLPYRIMIDINE;5-Cyano-4-aMino-2-MethylpyriMidine;2-methyl-4-amino-5-cyanopyrimidine;2-methyl-4-aminopyrimidine-5-nitrile;2-Methyl-4-aminopyrimidine-5-carbonitrile;4-Amino-2-methylpyrimidine-5-carbonitrile;5-Pyrimidinecarbonitrile, 4-amino-2-methyl-
CBNumber:
CB3477966
Molecular Formula:
C6H6N4
Molecular Weight:
134.14
MDL Number:
MFCD00084875
MOL File:
698-29-3.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:05
Request For Quotation

4-Amino-2-methylpyrimidine-5-carbonitrile Properties

Melting point 249 °C
Boiling point 315.6±27.0 °C(Predicted)
Density 1.27±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility DMSO, Ethanol, Methanol
pka 3.00±0.10(Predicted)
form Powder
color Pale yellow
Water Solubility Slightly soluble in water (6.4 g/L at 25°C). Soluble in dimethyl sulfoxide, ethanol and methanol.
InChI InChI=1S/C6H6N4/c1-4-9-3-5(2-7)6(8)10-4/h3H,1H3,(H2,8,9,10)
InChIKey YBPNIILOUYAGIF-UHFFFAOYSA-N
SMILES C1(C)=NC=C(C#N)C(N)=N1
CAS DataBase Reference 698-29-3(CAS DataBase Reference)
FDA UNII EH6ED3UPV9
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H312-H315-H319-H332-H335
Precautionary statements  P261-P280-P304+P340-P305+P351+P338-P405-P501a
target organs Respiratory system
Hazard Codes  Xi,Xn
Risk Statements  22-37/38-41
Safety Statements  26-39
WGK Germany  WGK 1
Hazard Note  Irritant
HazardClass  6.1
HS Code  2933599590
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3
REACH Registrations Active
NFPA 704
0
2 0

4-Amino-2-methylpyrimidine-5-carbonitrile price More Price(55)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological A1376-65 4-Amino-5-cyano-2-methylpyrimidine 698-29-3 1g $375 2026-06-03 Buy
TRC TRC-A603517-5G 4-Amino-5-cyano-2-methylpyrimidine 698-29-3 5g $479 2026-06-03 Buy
TRC TRC-A603517-2G 4-Amino-5-cyano-2-methylpyrimidine 698-29-3 2g $237 2026-06-03 Buy
TRC TRC-A603517-1G 4-Amino-5-cyano-2-methylpyrimidine 698-29-3 1g $129 2026-06-03 Buy
Activate Scientific AS47197 4-Amino-2-methylpyrimidine-5-carbonitrile 97% 698-29-3 1g $28 2026-06-04 Buy
Product number Packaging Price Buy
A1376-65 1g $375 Buy
TRC-A603517-5G 5g $479 Buy
TRC-A603517-2G 2g $237 Buy
TRC-A603517-1G 1g $129 Buy
AS47197 1g $28 Buy

4-Amino-2-methylpyrimidine-5-carbonitrile Chemical Properties,Uses,Production

Chemical Properties

Pale-Yellow Crystalline Solid

Uses

4-Amino-5-cyano-2-methylpyrimidine is used as a pharmaceutical intermediate.

Synthesis

To a clean 20L reaction flask, add 5kg of water, 5kg of ethanol and mix well. Take solid sodium hydroxide 1.8kg, add to the system and stir for 30min. until completely dissolved. Cool down the ice bath to below 25 degrees Celsius, add 3.2kg of acetamidine hydrochloride, basically no exothermic, white turbid liquid. After adding, stirring for 10min. dropwise addition of ethanol solution of dicyanoacetate, dropwise initial exothermic, insulation below 30 degrees Celsius, the back of the basic non-exothermic, can accelerate the acceleration of the drop. Dropping finished, warming to 65-70 reaction 1.5h. reaction solution while hot slowly poured into 10kg of ice water, stirring for 20min. treatment of liquid centrifuge centrifugation, get 4.6kg of wet product. 70-75 blast drying, to constant weight. Obtained white solid 3.6kg, liquid phase 98.2%, yield 85.7%.

4-Amino-2-methylpyrimidine-5-carbonitrile synthesis

50-00-0
124-42-5
109-77-3
698-29-3
Synthesis of 4-Amino-2-methylpyrimidine-5-carbonitrile from Formaldehyde and Acetamidine hydrochloride and Malononitrile

4-Amino-2-methylpyrimidine-5-carbonitrile Preparation Products And Raw materials

Raw materials

Acetamidine hydrochloride Sodium Ethoxymethylenemalononitrile Propanedinitrile, 2-[(acetyloxy)methylene]- 5-Pyrimidinecarbonitrile, 6-amino-1,4-dihydro-2-methyl-
Propanedinitrile, 2-[(diethylamino)methylene]- (aminomethylene)malononitrile (DIMETHYLAMINOMETHYLENE)MALONONITRILE Acetamidine Base (methoxymethylene)malononitrile
Methyl acetimidate hydrochloride Formaldehyde

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Preparation Products

5-Pyrimidinecarboxaldehyde, 4-amino-2-methyl- (6CI,7CI,8CI,9CI) 4-Pyrimidinamine, 2-methyl- (9CI)

4-Amino-2-methylpyrimidine-5-carbonitrile Suppliers

Global( 160)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Carbott PharmTech Inc. 0535-6385396 info@carbottpharm.com China 996 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Nanjing Vital Chemical Co., Ltd. Please Send Email 18652950785 chemweiao@163.com China 4368 65
Acorn PharmaTech Co., Ltd. 025-58395930 sales@acornpharma.com China 982 60
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9513 58
shanghai aokchem co., ltd 021-68712331 39130253 aokchem@gmail.com China 332 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Alfa Aesar 84
Carbott PharmTech Inc. 56
Capot Chemical Co., Ltd 66
Chemsky（shanghai）International Co.,Ltd. 50
Nanjing Vital Chemical Co., Ltd. 65
Acorn PharmaTech Co., Ltd. 60
Shanghai Topbiochem Technology Co., Ltd 58
shanghai aokchem co., ltd 58

View Lastest Price from 4-Amino-2-methylpyrimidine-5-carbonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE pictures 2026-08-20 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE
698-29-3
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE pictures 2026-06-30 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE
698-29-3
 1kg 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE pictures 2019-12-20 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE
698-29-3
 $1.00 1KG 97-99% 1000KGS Career Henan Chemical Co

4-Amino-2-methylpyrimidine-5-carbonitrile Spectrum

4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE(698-29-3)1HNMR

698-29-3(4-Amino-2-methylpyrimidine-5-carbonitrile)Related Search:

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4-AMINO-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBONITRILE 4-Amino-2-(3-pyridyl)pyrimidine-5-carbonitrile 4-AMINO-6-METHOXY-2-METHYLPYRIMIDINE-5-CARBONITRILE 4-AMINO-5-CYANO-2,6-DIMETHYLPYRIMIDINE 4-Amino-2-(4-methylphenyl)-6-(methylthio)pyrimidine-5-carbonitrile
4-Amino-6-methylpyrimidine-5-carbonitrile ,97% 4-(4-CHLOROPHENYL)-6-(METHYLAMINO)-2-(3-PYRIDINYL)-5-PYRIMIDINECARBONITRILE 4-(ISOPROPYLAMINO)-6-PHENYL-2-(3-PYRIDINYL)-5-PYRIMIDINECARBONITRILE 4-MORPHOLINO-6-PHENYL-2-(3-PYRIDINYL)-5-PYRIMIDINECARBONITRILE 4-(4-CHLOROPHENYL)-6-(ISOPROPYLAMINO)-2-(4-PYRIDINYL)-5-PYRIMIDINECARBONITRILE
4-(Dimethylamino)-6-phenyl-2-(4-pyridinyl)-5-pyrimidinecarbonitrile 4-(4-Chlorophenyl)-6-(diethylamino)-2-phenyl-5-pyrimidinecarbonitrile 4-(Isopropylamino)-6-phenyl-2-(4-pyridinyl)-5-pyrimidinecarbonitrile

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4-AMINO-5-CYANO-2-METHYLPYRIMIDINE BUTTPARK 27\08-63 2-Methyl-4-aminopyrimidine-5-carbonitrile 5-Pyrimidinecarbonitrile, 4-amino-2-methyl- (6CI,7CI,8CI,9CI) 5-Cyano-4-aMino-2-MethylpyriMidine NSC 459 Pynitrile 4-Amino-5-cyano-2-methylpyrimidine, 4-Amino-5-cyano-2-methyl-1,3-diazine 4-Amino-2-methylpyrimidine-5-carbonitrile 98% 5-Pyrimidinecarbonitrile, 4-amino-2-methyl- 4-Amino-2-methylpyrimidine-5-carbonitrile98% 2-methyl-4-amino-5-cyanopyrimidine 4-AMINO-2-METHYLPYRIMIDINE-5-CARBONITRILE ISO 9001：2015 REACH 2-methyl-4-aminopyrimidine-5-nitrile 4-Amino-2-methylpyrimidine-5-carbonitrile 698-29-3 C6H6N4 Amines Aromatics Heterocycles PYRIMIDINE Pyrazines, Pyrimidines & Pyridazines Nucleotides and Nucleosides Bases & Related Reagents Nucleotides Pyrazines, Pyrimidines & Pyridazines