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BMS-908662

BMS-908662 Structure
BMS-908662 structure
CAS No.
870603-16-0
Chemical Name:
BMS-908662
Synonyms
BMS-908662;BMS-908662(1X-281);Carbamic acid, N-[6-[2-(5-chloro-2-methylphenyl)-2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl]-1H-benzimidazol-2-yl]-, methyl ester
CBNumber:
CB34919927
Molecular Formula:
C24H19ClN4O4
Molecular Weight:
462.89
MDL Number:
MOL File:
870603-16-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-21 10:31:43
Product description Number Pack Size Price
XL-281 CS-0015416 1mg $590
XL-281 CS-0015416 5mg $1466
XL-281 CS-0015416 10mg $2124
XL-281 CS-0015416 1mg $590
XL-281 CS-0015416 5mg $1466
Request For Quotation

BMS-908662 Properties

Density 1.526±0.06 g/cm3(Predicted)
pka 10.77±0.20(Predicted)
FDA UNII DW2NWI3TFN

BMS-908662 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0015416 XL-281 870603-16-0 1mg $590 2026-06-04 Buy
ChemScene CS-0015416 XL-281 870603-16-0 5mg $1466 2026-06-04 Buy
ChemScene CS-0015416 XL-281 870603-16-0 10mg $2124 2026-06-04 Buy
ChemScene CS-0015416 XL-281 870603-16-0 1mg $590 2026-06-04 Buy
ChemScene CS-0015416 XL-281 870603-16-0 5mg $1466 2026-06-04 Buy
Product number Packaging Price Buy
CS-0015416 1mg $590 Buy
CS-0015416 5mg $1466 Buy
CS-0015416 10mg $2124 Buy
CS-0015416 1mg $590 Buy
CS-0015416 5mg $1466 Buy

BMS-908662 Chemical Properties,Uses,Production

Uses

XL-281 (BMS-908662) is an orally active inhibitor for RAF kinase, with IC50s of 2.6, 4.5 and 6 nM, for CRAF, B-RAF, and B-RAFV600E, respectively. XL-281 exhibits antitumor activity[1].

IC 50

c-Raf: 2.6 nM (IC50); B-Raf: 4.5 nM (IC50); B-RafV600E: 6 nM (IC50)

References

[1] Dickson MA, et al., Phase I study of XL281 (BMS-908662), a potent oral RAF kinase inhibitor, in patients with advanced solid tumors. Invest New Drugs. 2015 Apr;33(2):349-56. DOI:10.1007/s10637-014-0191-5

BMS-908662 Preparation Products And Raw materials

Raw materials

Preparation Products

BMS-908662 Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32466 58
BOC Sciences 		16314854226; +16314854226 inquiry@bocsci.com United States 19853 58
NANJING YINGWEN BIOTECHNOLOGY CO LTD 		+8613382787392 sales@aeechem.com China 10001 58
Chengdu Novel Biomedical Co., Ltd. 028-85255396 18302801538 cdnovell@163.com China 2424 58
Chunchuang (Wuhan) Technology Co., Ltd 15727060112 yutianchun2007@126.com China 9863 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24955 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 6000 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11972 58
Zhengzhou Haode Pharmaceutical Technology Co.,Ltd 18037386321 3330511471@qq.com China 500 58
Shanghai Amole Biotechnology Co., Ltd. 18916360931 18916360931 2596183085@qq.com China 17238 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
BOC Sciences 		58
NANJING YINGWEN BIOTECHNOLOGY CO LTD 		58
Chengdu Novel Biomedical Co., Ltd. 58
Chunchuang (Wuhan) Technology Co., Ltd 58
TargetMol Chemicals Inc. 58
Nantong QuanYi Biotechnology Co., Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Zhengzhou Haode Pharmaceutical Technology Co.,Ltd 58
Shanghai Amole Biotechnology Co., Ltd. 58

View Lastest Price from BMS-908662 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Xl-281 pictures 2026-04-20 Xl-281
870603-16-0
 $293.00-987.00 98.83% 10g TargetMol Chemicals Inc.
  • Xl-281 pictures
  • Xl-281
    870603-16-0
  • $293.00-987.00
  • 98.83%
  • TargetMol Chemicals Inc.

BMS-908662 Spectrum

BMS-908662(870603-16-0)1HNMR

870603-16-0(BMS-908662)Related Search:

XL 228 XL-019 XL413 (hydrochloride) 3-Acridinecarboxamide, 9-chloro-5,6,7,8-tetrahydro-N-[(4S)-5-[4-hydroxy-4-[[7-[[3-(4-methyl-1-piperazinyl)-1-oxopropyl]amino]-4-oxo-3(4H)-quinazolinyl]methyl]-1-piperidinyl]-5-oxo-4-(phenylmethyl)pentyl]- XL-388
XL888 XL765 2-methoxyethyl 4-((4-(4-chlorophenoxy)-3,5-difluorophenyl)sulfonyl)-3-(hydroxycarbamoyl)piperazine-1-carboxylate

1of2

BMS-908662 Carbamic acid, N-[6-[2-(5-chloro-2-methylphenyl)-2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl]-1H-benzimidazol-2-yl]-, methyl ester BMS-908662(1X-281) 870603-16-0