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4-(Diethylamino)salicylaldehyde

4-(Diethylamino)salicylaldehyde Structure
4-(Diethylamino)salicylaldehyde structure
CAS No.
17754-90-4
Chemical Name:
4-(Diethylamino)salicylaldehyde
Synonyms
4-(diethylamino)salicyladehyde;4-Diethylamino-2-hydroxybenzaldehyde;2-Hydroxy-4-diethylaminobenzaldehyde;-6-;4(3H;6+3);amino)saL;5]thieno[2;8-tetrahydro-2;4-d]pyriMidine-2
CBNumber:
CB3499007
Molecular Formula:
C11H15NO2
Molecular Weight:
193.24
MDL Number:
MFCD00003326
MOL File:
17754-90-4.mol
MSDS File:
SDS
Last updated:2026-05-28 02:29:33
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4-(Diethylamino)salicylaldehyde Properties

Melting point 60-62 °C (lit.)
Boiling point 329.46°C (rough estimate)
Density 1.0945 (rough estimate)
refractive index 1.5041 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka 8.29±0.10(Predicted)
form Powder or Crystalline Powder
color Pale brown to pink to purple
Water Solubility Insoluble in water.
Sensitive Air Sensitive
BRN 2212234
InChIKey XFVZSRRZZNLWBW-UHFFFAOYSA-N
CAS DataBase Reference 17754-90-4(CAS DataBase Reference)
FDA UNII OU5NFU4681
EPA Substance Registry System Benzaldehyde, 4-(diethylamino)-2-hydroxy- (17754-90-4)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
WGK Germany  2
RTECS  CU5615150
TSCA  TSCA listed
HS Code  29225090
NFPA 704
1
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4-(Diethylamino)salicylaldehyde price More Price(110)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 225681 4-(Diethylamino)salicylaldehyde 98% 17754-90-4 5g $53.7 2026-04-30 Buy
Sigma-Aldrich 225681 4-(Diethylamino)salicylaldehyde 98% 17754-90-4 25g $82.2 2026-04-30 Buy
TCI Chemical D1752 4-(Diethylamino)salicylaldehyde >98.0%(GC)(T) 17754-90-4 25g $32 2026-04-30 Buy
TCI Chemical D1752 4-(Diethylamino)salicylaldehyde min. 98.0 % 17754-90-4 100G $64 2026-04-30 Buy
TCI Chemical D1752 4-(Diethylamino)salicylaldehyde >98.0%(GC)(T) 17754-90-4 250g $129 2026-04-30 Buy
Product number Packaging Price Buy
225681 5g $53.7 Buy
225681 25g $82.2 Buy
D1752 25g $32 Buy
D1752 100G $64 Buy
D1752 250g $129 Buy

4-(Diethylamino)salicylaldehyde Chemical Properties, Uses, Production

Chemical Properties

4-(Diethylamino)salicylaldehyde is beige to purple crystalline powder

Uses

4-(Diethylamino)salicylaldehyde is usually used in the synthesis of Schiff-base ligand by monocondensation with diaminomaleonitrile.

Uses

4-(Diethylamino)salicylaldehyde was used in the synthesis of Schiff-base ligand by monocondensation with diaminomaleonitrile.

Definition

ChEBI: 4-(Diethylamino)salicylaldehyde is a hydroxybenzaldehyde.

Synthesis

N,N-Dimethylformamide

68-12-2

3-Diethylaminophenol

91-68-9

4-(Diethylamino)salicylaldehyde

17754-90-4

The temperature of the reaction system was maintained at 5-10 °C under continuous stirring and phosphorus oxychloride (POCl3, 2.75 mL, 0.03 mol) was slowly added dropwise to N,N-dimethylformamide (DMF, 3.65 mL, 0.05 mol). Subsequently, 3-(N,N-diethylamino)phenol (0.01 mmol) dissolved in DMF (6 mL) was slowly added to the above cooled mixture at the same temperature. The reaction mixture was stirred at a constant temperature at 75 °C for 4 hours. After the reaction was completed, the mixture was cooled to room temperature and slowly poured into 60 mL of ice water. The reaction mixture was neutralized with sodium carbonate solution and a brown solid precipitated. The solid product was collected by filtration, washed with cold water, dried and recrystallized from ethanol to give the pure 4-(diethylamino)salicylaldehyde in 80% yield with a melting point of 62 °C (literature value: 62 °C).

References

[1] Organic and Biomolecular Chemistry, 2017, vol. 15, # 12, p. 2575 - 2584
[2] Journal of Fluorescence, 2015, vol. 25, # 6, p. 1615 - 1628
[3] Chemical Communications, 2016, vol. 52, # 60, p. 9434 - 9437
[4] Chemistry Letters, 2011, vol. 40, # 3, p. 279 - 281
[5] Patent: US2789125, 1953,

4-(Diethylamino)salicylaldehyde Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide 3-Diethylaminophenol Phosphorus oxitrichloride 2-Benzyloxy-4-diethylaminobenzaldehyde

Preparation Products

COUMARIN 7 Solvent Red 196 Solvent Red 197 7-(diethylaMino)-2-oxo-2H-chroMene-3-carbaldehyde COUMARIN 7
Disperse Red 186 2-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]quinazolin-4(1H)-one Disperse Yellow 232 3-(1H-benzoimidazol-2-yl)-N,N-diethyl-2-imino-chromen-7-amine 2-Hydroxy-benzoic acid 2-[[4-(diethylamino)-2-hydroxyphenyl]methylene]hydrazide

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4-(Diethylamino)salicylaldehyde Suppliers

Global Suppliers ( 320)
Supplier Tel Email Country ProdList Advantage
Taizhou zhenhe chemical co. LTD 576-88887792 13386577269 sales@zhenhechemical.com China 115 58
Taizhou Jiecheng Chemical Co., Ltd. 0576-88203651 15967007102 103858443@qq.com China 270 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
SelectLab Chemicals GmbH +49-(0)2383-919350 info@selectlab.de Germany 393 55
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9409 55
Supplier Advantage
Taizhou zhenhe chemical co. LTD 58
Taizhou Jiecheng Chemical Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
SelectLab Chemicals GmbH 55
Alfa Aesar 84
TAIYUAN RHF CO.,LTD. 56
TCI (Shanghai) Development Co., Ltd. 81
ShangHai DEMO Chemical Co.,Ltd 57
Beijing HwrkChemical Technology Co., Ltd 55

View Latest Price from 4-(Diethylamino)salicylaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(Diethylamino)salicylaldehyde pictures 2026-06-30 4-(Diethylamino)salicylaldehyde
17754-90-4
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
4-(Diethylamino)salicylaldehyde pictures 2026-02-02 4-(Diethylamino)salicylaldehyde
17754-90-4
 10mg 99%HPLC 2000tons Shaanxi Dideu Medichem Co. Ltd
4-(Diethylamino)salicylaldehyde pictures 2025-06-27 4-(Diethylamino)salicylaldehyde
17754-90-4
 $10.00-30.00 50KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd

4-(Diethylamino)salicylaldehyde Spectrum

4-(Diethylamino)salicylaldehyde(17754-90-4)MS4-(Diethylamino)salicylaldehyde(17754-90-4)1HNMR4-(Diethylamino)salicylaldehyde(17754-90-4)13CNMR4-(Diethylamino)salicylaldehyde(17754-90-4)IR14-(Diethylamino)salicylaldehyde(17754-90-4)IR2

17754-90-4 (4-(Diethylamino)salicylaldehyde) Related Search:

3-Hydroxybenzaldehyde 2-Aminoacetophenone 4-Diethylaminobenzaldehyde 1-Hydroxyethylidene-1,1-diphosphonic acid Acetaminophen
2,4-Dihydroxybenzaldehyde 4-Aminobenzaldehyde 4-Aminoacetophenone 4-Dimethylaminobenzaldehyde Taurine
4-Hydroxybenzaldehyde Salicylaldehyde Diethylaminoethanol Dimethylaminobenzaldehyde Acetaminophenol BP/USP
4-(Diethylamino)salicylaldehyde 4-(Diethylamino)salicylaldehyde

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3-[1-[1-(diethylamino)-4-formyl-3-hydroxy-1-cyclohexa-2,4-dienyl]ethyl-ethylamino]-2-hydroxybenzaldehyde Ouabain-dx (x &ge 4-(Diethylamino)salicylaldehyde(DEMAP ALDEHYDE) TIZANIDINE IMPURITY 6 6-Hydroxy Ondansetron HCl GABAA Ralpha6 (Gamma-aminobutyric acid Receptor Subunit alpha-6, GABA(A) Receptor Subunit alpha-6, GABRA6, GABAAR&alpha Fluticasone furoate impurity 6 4-(diethylamino)-2-hydroxy-benzaldehyd 4-(diethylamino)salicyladehyde 4-(diethylamino)-salicylaldehyd 4-diethyllamino-salicylaldhyde 4-N,N-Diethylaminosalicylicaldehyde -6- benzaldehyde,-(diethylamino)-2-hydroxy- Salicylaldehyde, 4-(diethylamino)- (6CI,8CI) p-(diethylamino)salicylaldehyde 4-(DIETHYLAMINO)SALICYLALDEHYDE 98 4-Dimethylamino-2-Hydroxybenzaldehyde98% 4-(Diethylamino)salicylaldehyde 4-Diethylamino-2-hydroxybenzaldehyde 4-(DIETHYLAMINO)SALICYLALDEHYDE 95+% 4-(Diethylamino)salicylaldehyde,4-Diethylamino-2-hydroxybenzaldehyde 4-(Diethylamino)sali N-DiethylaMino)salicylaldehyde 6-naphthyridin-1(2H)-one hydrochloride 8-tetrahydro-2 3-d]-pyriMidin-4-one 5]thieno[2 8-Tetrahydro-3H-benzo[4 4(3H 4-d]pyriMidine-2 5H)-dione hydrochloride 7-dihydro-1H-pyrrolo[3 6-benzyl-2-chloro-5 7-tetrahydrobenzofuran-3-carboxylate hydrochloride Methyl 4-aMino-4 4-(Diethylamino)salicylaldehyde ,99% Benzaldehyde,4-(diethylaMino)-2-hydroxy- 4-(Er YisalicylaldehydeaMino) 4-(Diethylamino)salicylaldehyde, 5-(Diethylamino)-2-formylphenol 4-(Diethylamino)salicylaldehyde> amino)saL TIANFUCHEM--17754-90-4--High purity 4-(Diethylamino)salicylaldehyde factory price 6+3) 2-Hydroxy-4-diethylaminobenzaldehyde 17754-90-4 147548-85-3 C2H52NC6H32OHCHO Heterocyclic Compounds Aromatic Aldehydes & Derivatives (substituted) Elisa Kit-Mouse Elisa Kit