4-(Diethylamino)salicylaldehyde
- CAS No.
- 17754-90-4
- Chemical Name:
- 4-(Diethylamino)salicylaldehyde
- Synonyms
- 4-(diethylamino)salicyladehyde;4-Diethylamino-2-hydroxybenzaldehyde;-6-;4(3H;6+3);amino)saL;5]thieno[2;8-tetrahydro-2;4-d]pyriMidine-2;Methyl 4-aMino-4
- CBNumber:
- CB3499007
- Molecular Formula:
- C11H15NO2
- Molecular Weight:
- 193.24
- MDL Number:
- MFCD00003326
- MOL File:
- 17754-90-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-(Diethylamino)salicylaldehyde 98% | 225681 | 5g | $50.4 |
| 4-(Diethylamino)salicylaldehyde 98% | 225681 | 25g | $77.1 |
| 4-(Diethylamino)salicylaldehyde >98.0%(GC)(T) | D1752 | 25g | $32 |
| 4-(Diethylamino)salicylaldehyde >98.0%(GC)(T) | D1752 | 250g | $129 |
| 6- | 277937 | 250mg | $368 |
| More product size | |||
| Melting point | 60-62 °C (lit.) |
|---|---|
| Boiling point | 329.46°C (rough estimate) |
| Density | 1.0945 (rough estimate) |
| refractive index | 1.5041 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 8.29±0.10(Predicted) |
| form | Powder or Crystalline Powder |
| color | Pale brown to pink to purple |
| Water Solubility | Insoluble in water. |
| Sensitive | Air Sensitive |
| BRN | 2212234 |
| InChIKey | XFVZSRRZZNLWBW-UHFFFAOYSA-N |
| CAS DataBase Reference | 17754-90-4(CAS DataBase Reference) |
| FDA UNII | OU5NFU4681 |
| EPA Substance Registry System | Benzaldehyde, 4-(diethylamino)-2-hydroxy- (17754-90-4) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | CU5615150 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29225090 | |||||||||
| NFPA 704 |
|
4-(Diethylamino)salicylaldehyde price More Price(79)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 225681 | 4-(Diethylamino)salicylaldehyde 98% | 17754-90-4 | 5g | $50.4 | 2025-07-31 | Buy |
| Sigma-Aldrich | 225681 | 4-(Diethylamino)salicylaldehyde 98% | 17754-90-4 | 25g | $77.1 | 2025-07-31 | Buy |
| TCI Chemical | D1752 | 4-(Diethylamino)salicylaldehyde >98.0%(GC)(T) | 17754-90-4 | 25g | $32 | 2025-07-31 | Buy |
| TCI Chemical | D1752 | 4-(Diethylamino)salicylaldehyde >98.0%(GC)(T) | 17754-90-4 | 250g | $129 | 2025-07-31 | Buy |
| Usbiological | 277937 | 6- | 17754-90-4 | 250mg | $368 | 2021-12-16 | Buy |
4-(Diethylamino)salicylaldehyde Chemical Properties,Uses,Production
Chemical Properties
4-(Diethylamino)salicylaldehyde is beige to purple crystalline powder
Uses
4-(Diethylamino)salicylaldehyde is usually used in the synthesis of Schiff-base ligand by monocondensation with diaminomaleonitrile.
Uses
4-(Diethylamino)salicylaldehyde was used in the synthesis of Schiff-base ligand by monocondensation with diaminomaleonitrile.
Definition
ChEBI: 4-(Diethylamino)salicylaldehyde is a hydroxybenzaldehyde.
Synthesis
68-12-2
91-68-9
17754-90-4
The temperature of the reaction system was maintained at 5-10 °C under continuous stirring and phosphorus oxychloride (POCl3, 2.75 mL, 0.03 mol) was slowly added dropwise to N,N-dimethylformamide (DMF, 3.65 mL, 0.05 mol). Subsequently, 3-(N,N-diethylamino)phenol (0.01 mmol) dissolved in DMF (6 mL) was slowly added to the above cooled mixture at the same temperature. The reaction mixture was stirred at a constant temperature at 75 °C for 4 hours. After the reaction was completed, the mixture was cooled to room temperature and slowly poured into 60 mL of ice water. The reaction mixture was neutralized with sodium carbonate solution and a brown solid precipitated. The solid product was collected by filtration, washed with cold water, dried and recrystallized from ethanol to give the pure 4-(diethylamino)salicylaldehyde in 80% yield with a melting point of 62 °C (literature value: 62 °C).
References
[1] Organic and Biomolecular Chemistry, 2017, vol. 15, # 12, p. 2575 - 2584
[2] Journal of Fluorescence, 2015, vol. 25, # 6, p. 1615 - 1628
[3] Chemical Communications, 2016, vol. 52, # 60, p. 9434 - 9437
[4] Chemistry Letters, 2011, vol. 40, # 3, p. 279 - 281
[5] Patent: US2789125, 1953,
4-(Diethylamino)salicylaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21599 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29833 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2161 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
View Lastest Price from 4-(Diethylamino)salicylaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-01-05 | 4-(Diethylamino)salicylaldehyde
17754-90-4
|
US $0.00-0.00 / KG | 10mg | 99%HPLC | 2000tons | Shaanxi Dideu Medichem Co. Ltd | |
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2025-12-01 | 4-(Diethylamino)salicylaldehyde
17754-90-4
|
US $0.00 / kg | 1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
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2025-06-27 | 4-(Diethylamino)salicylaldehyde
17754-90-4
|
US $30.00-10.00 / KG | 50KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd |
-

- 4-(Diethylamino)salicylaldehyde
17754-90-4
- US $0.00-0.00 / KG
- 99%HPLC
- Shaanxi Dideu Medichem Co. Ltd
-

- 4-(Diethylamino)salicylaldehyde
17754-90-4
- US $0.00 / kg
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-

- 4-(Diethylamino)salicylaldehyde
17754-90-4
- US $30.00-10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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