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Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate structure

CAS No.: 887267-53-0

Chemical Name:: Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate

Synonyms: Ethyl 3-(2,5-difluorophenyl);ETHYL 2,5-DIFLUOROBENZOYLACETATE;Ethyl 2,5-difluoro-β-oxobenzenepropanoate;ETHYL 3-(2,5-DIFLUOROPHENYL)-3-OXOPROPANOATE;Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate 95+%;Benzenepropanoic acid, 2,5-difluoro-β-oxo-, ethyl ester;3-(2,5-Difluoro-phenyl)-3-oxo-propionic acid ethyl ester;2-fluoro-3-(3-fluorophenyl)-3-oxopropanoic acid ethyl ester

CBNumber:: CB3689431

Molecular Formula:: C11H10F2O3

Molecular Weight:: 228.19

MDL Number:: MFCD07783808

MOL File:: 887267-53-0.mol

MSDS File:: SDS

Last updated:2026-05-28 04:27:11

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Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Properties

Boiling point	275.7±25.0 °C(Predicted)
Density	1.251±0.06 g/cm3(Predicted)
storage temp.	Storage temp. 2-8°C
pka	10.28±0.50(Predicted)
Appearance	Colorless to light yellow Liquid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319
Precautionary statements	P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
HS Code	2916399090

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Apolloscientific	PC1843	Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate 97%	887267-53-0	250mg	$21	2026-06-04	Buy
Apolloscientific	PC1843	Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate 97%	887267-53-0	1g	$24	2026-06-04	Buy
Apolloscientific	PC1843	Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate 97%	887267-53-0	5g	$79	2026-06-04	Buy
Apolloscientific	PC1843	Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate 97%	887267-53-0	25g	$381	2026-06-04	Buy
Apolloscientific	PC1843	Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate 97%	887267-53-0	100g	$1393	2026-06-04	Buy

Product number	Packaging	Price	Buy
PC1843	250mg	$21	Buy
PC1843	1g	$24	Buy
PC1843	5g	$79	Buy
PC1843	25g	$381	Buy
PC1843	100g	$1393	Buy

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Chemical Properties, Uses, Production

Uses

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate is commonly utilized in organic synthesis as C-nucleophiles. One specific example is its reaction with the N-terminal electrophile CF3CHN2, resulting in the formation of CF3-heterocycles, namely ethyl 6-fluoro-4-oxo-1-(2,2,2-trifluoroethyl)-1,4-dihydrocinnoline-3-carboxylate[1].
Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate

References

[1] Arkhipov A, et al. Unexpected Reactivity of Trifluoromethyl Diazomethane (CF3CHN2): Electrophilicity of the Terminal NAtom. Organic Letters, 2016; 18: 3406–3409.

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Preparation Products And Raw materials

Raw materials

Preparation Products

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Suppliers

Global Suppliers ( 62)

Supplier	Tel	Email	Country	ProdList	Advantage
Amatek Scientific Co. Ltd.	0512-56316828 4008675858	sales@amateksci.com	China	9849	55
Cochemical Ltd.	029-86115547 17791676824	sales@cochemical.com	China	3014	58
Cool Pharm, Ltd	021-60455363 18019463053	sales@coolpharm.com	China	8455	58
Tongling HengYou Biotechnology Co., Ltd.	021-50426030 13856289449;13124863828	2630597085@qq.com	China	1885	55
JW & Y Pharmlab Co., Ltd.	021-64340559	xinyu_shi@jwypharmlab.com.cn	China	11999	58
ShangHai Angti Biotechnology Co., Ltd.	13764913901	info@angtibio.com	China	4975	55
Shanghai TuZhi Chemical Co., Ltd.	19542790274	2119559397@qq.com	China	751	50
TaiChem Taizhou Limited	052386810091	zcwy9518@yeah.net	China	3917	58
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58

Supplier	Advantage
Amatek Scientific Co. Ltd.	55
Cochemical Ltd.	58
Cool Pharm, Ltd	58
Tongling HengYou Biotechnology Co., Ltd.	55
JW & Y Pharmlab Co., Ltd.	58
ShangHai Angti Biotechnology Co., Ltd.	55
Shanghai TuZhi Chemical Co., Ltd.	50
TaiChem Taizhou Limited	58
Shanghai YuanYe Biotechnology Co., Ltd.	60
Amadis Chemical Company Limited	58

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Spectrum

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate(887267-53-0)¹HNMR

887267-53-0 (Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate) Related Search:

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ETHYL 3-(2,5-DIFLUOROPHENYL)-3-OXOPROPANOATE ETHYL 2,5-DIFLUOROBENZOYLACETATE 3-(2,5-Difluoro-phenyl)-3-oxo-propionic acid ethyl ester Ethyl 3-(2,5-difluorophenyl) 2-fluoro-3-(3-fluorophenyl)-3-oxopropanoic acid ethyl ester Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate 95+% Benzenepropanoic acid, 2,5-difluoro-β-oxo-, ethyl ester Ethyl 2,5-difluoro-β-oxobenzenepropanoate 887267-53-0