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2,4,5-Trichlorophenol

2,4,5-Trichlorophenol Structure
2,4,5-Trichlorophenol structure
CAS No.
95-95-4
Chemical Name:
2,4,5-Trichlorophenol
Synonyms
Phenol, 2,4,5-trichloro-;Nurelle;Dowcide;Dowcide 2;2,4,5-tcp;NCI-C61187;preventoli;COLLUNOSOL;DOWICIDE 2;Preventol I
CBNumber:
CB3714348
Molecular Formula:
C6H3Cl3O
Molecular Weight:
197.45
MDL Number:
MFCD00002170
MOL File:
95-95-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-20 15:44:50
Product description Number Pack Size Price
2,4,5-Trichlorophenol purum, ≥95.0% (GC) 91332 50g $95
2,4,5-Trichlorophenol 95% 156515 25g $78.6
2,4,5-Trichlorophenol 95% 156515 100g $286
2,4,5-Trichlorophenol >95.0%(GC) T0389 25g $38
2,4,5-Trichlorophenol >95.0%(GC) T0389 500g $333
More product size
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2,4,5-Trichlorophenol Properties

Melting point 64-67 °C 67-69 °C (lit.)
Boiling point 248 °C/740 mmHg (lit.)
Density 1,678 g/cm3
vapor pressure 3.5 at 8 °C, 22 at 25 °C (quoted, Leuenberger et al., 1985a)
refractive index 1.5300 (estimate)
Flash point 253°C
storage temp. 2-8°C
solubility Soluble in ethanol and ligroin (U.S. EPA, 1985)
pka pK1:7.37 (25°C)
form Powder
color Colorless needles or gray flakes from pet ether
Odor strong phenolic odor
Water Solubility 947.8mg/L(25 ºC)
Merck 14,9643
BRN 607569
Henry's Law Constant 1.76 at 25 °C (estimated, Leuenberger et al., 1985a)
Stability Stable. Note that this material creates dioxin in alkaline media at elevated temperatures.
Major Application agriculture
environmental
InChI 1S/C6H3Cl3O/c7-3-1-5(9)6(10)2-4(3)8/h1-2,10H
InChIKey LHJGJYXLEPZJPM-UHFFFAOYSA-N
SMILES Oc1cc(Cl)c(Cl)cc1Cl
CAS DataBase Reference 95-95-4(CAS DataBase Reference)
EWG's Food Scores 4
FDA UNII 32526637PN
NIST Chemistry Reference Phenol, 2,4,5-trichloro-(95-95-4)
EPA Substance Registry System 2,4,5-Trichlorophenol (95-95-4)
Toxicological Profile|ATSDR 2,4,5-Trichlorophenol|Toxicological Profile|ATSDR
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08,GHS09
Signal word  Warning
Hazard statements  H302-H315-H319-H361-H335-H336-H410
Precautionary statements  P501-P261-P273-P270-P202-P201-P271-P264-P280-P302+P352-P391-P308+P313-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P304+P340+P312-P403+P233-P405
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,N,Xi,T,F
Risk Statements  22-36/38-50/53-52/53-39/23/24/25-23/24/25-11-51/53
Safety Statements  26-28-60-61-28A-45-36/37-16
RIDADR  UN 3077 9/PG 3
WGK Germany  3
RTECS  SN1400000
TSCA  TSCA listed
HazardClass  6.1
PackingGroup  III
HS Code  29081990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
Eye Irrit. 2
Skin Irrit. 2
Hazardous Substances Data 95-95-4(Hazardous Substances Data)
Toxicity Acute oral LD50 for guinea pigs 1,000 mg/kg, mice 600 mg/kg, rats 820 mg/kg (quoted, RTECS, 1985).
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
1
2 0

2,4,5-Trichlorophenol price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 91332 2,4,5-Trichlorophenol purum, ≥95.0% (GC) 95-95-4 50g $95 2026-04-30 Buy
Sigma-Aldrich 156515 2,4,5-Trichlorophenol 95% 95-95-4 25g $78.6 2026-04-30 Buy
Sigma-Aldrich 156515 2,4,5-Trichlorophenol 95% 95-95-4 100g $286 2026-04-30 Buy
TCI Chemical T0389 2,4,5-Trichlorophenol >95.0%(GC) 95-95-4 25g $38 2026-04-30 Buy
TCI Chemical T0389 2,4,5-Trichlorophenol >95.0%(GC) 95-95-4 500g $333 2026-04-30 Buy
Product number Packaging Price Buy
91332 50g $95 Buy
156515 25g $78.6 Buy
156515 100g $286 Buy
T0389 25g $38 Buy
T0389 500g $333 Buy

2,4,5-Trichlorophenol Chemical Properties,Uses,Production

Chemical Properties

White to pale brown solid in appearance; 2,4,5-Trichlorophenol also looks like small needles. It has a really strong odor that smells like phenol (a poisonous crystal-looking compound). This man-made substance is not found naturally in the environment.

Physical properties

Colorless crystals or yellow to gray flakes with a strong, disinfectant or phenolic odor. At 40 °C, the average odor threshold concentration and the lowest concentration at which an odor were detected were 350 and 63 μg/L, respectively. At 25 °C, the lowest concentration at which a taste was detected was 100 μg/L (Young et al., 1996).

Uses

2,4,5-Trichlorophenol is used as a broad range pesticide against insects, fungi, vegetation and bacteria. It has become a common environmental contaminant and probable human carcinogen.

Definition

ChEBI: 2,4,5-trichlorophenol is a trichlorophenol carrying chloro groups at positions 2, 4 and 5.

Preparation

2,4,5-Trichlorophenol is prepared indirectly, by the alkaline hydrolysis of 1,2,4,5-tetrachlorobenzene,because the direct chlorination of 2,5-dichlorophenol, difficult to achieve, proceeds with poor yield.

General Description

Colorless needles, gray flakes or off-white lumpy solid. Phenolic odor. Formerly used as a fungicide and bactericide.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2,4,5-Trichlorophenol is a weak monobasic acid. Incompatible with acid chlorides, acid anhydrides and oxidizing agents. Produces dioxin in alkaline medium at high temperatures

Health Hazard

If your skin comes into contact with 2,4,5-trichlorophenol, it may burn the skin and produce redness and edema in humans. It also irritates the eyes, nose, pharynx, and lungs in humans.
Tests involving acute exposure of rats, mice, and guinea pigs have demonstrated 2,4,5-trichlorophenol to havemoderateacute toxicity by oral exposure.

Fire Hazard

Literature sources indicate that 2,4,5-Trichlorophenol is nonflammable.

Safety Profile

Suspected carcinogen with experimental neoplastigenic data. Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Cland explodes. See also CHLOROPHENOLS.

Environmental Fate

Biological. Chloroperoxidase, a fungal enzyme isolated from Caldariomyces fumago, chlorinated 2,4,5-trichlorophenol to give 2,3,4,6-tetrachlorophenol (Wannstedt et al., 1990).
Photolytic. When 2,4,5-trichlorophenol (100 μM) in an oxygenated, titanium dioxide (2 g/L) suspension was irradiated by sunlight (λ ≥340 nm), complete mineralization to carbon dioxide and water and chloride ions was observed (Barbeni et al., 1987a).
The following phototransformation half-lives were reported for 2,4,5-trichlorophenol in estuarine water exposed to sunlight and microbes: 1 h during winter; in distilled water: 0.6 and 1 h during summer and winter, respectively; in poisoned estuarine water: 14 and 24 h during summer and winter, respectively (Hwang et al., 1986).
A photooxidation rate constant of <3,000/M·sec was reported for the reaction of 2,4,5- trichlorophenol and ozone in water at a pH range of 1.2 to 1.5 (Hoigné and Bader, 1983). Chemical/Physical. 2,4,5-Trichlorophenol will not hydrolyze because it does not contain a hydrolyzable functional group (Kollig, 1993).
During the manufacture/synthesis of 2,4,5-T using alkalies at high temperatures, some TCDD may form (Worthing and Hance, 1991).

Purification Methods

Crystallise the phenol from EtOH or pet ether. [Beilstein 6 IV 962.]

Toxics Screening Level

The current ITSL for 2,4,5-Trichlorophenol is 350 μg/m3 , with annual averaging time (AT).

2,4,5-Trichlorophenol synthesis

636-30-6
95-95-4
Synthesis of 2,4,5-Trichlorophenol from 2,4,5-Trichloroaniline

2,4,5-Trichlorophenol Preparation Products And Raw materials

Raw materials

Sodium dithionite 1,2,3,5-Tetrachlorobenzene Toluene Sodium tetraborate 1,2,4,5-Tetrachlorobenzene
Sodium hydroxide Propylene glycol Sulfuric acid CARBONIC ACID TERT-BUTYL 2,4,5-TRICHLOROPHENYL ESTER 2,3,4,6-TETRACHLOROPHENOL

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Preparation Products

FENCHLORPHOS HALOPROGIN 2,4,5-Trichlorophenyl-propynyl ether Hexachlorophene Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-(ethoxymethylphosphinyl)-, (2S)- (9CI)
FENCHLORPHOS-OXON 2,5-DICHLOROHYDROQUINONE Trimethyl phosphate 2,4,5-Trichlorophenoxyacetic acid 2,3,6-trichlorophenol

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2,4,5-Trichlorophenol Suppliers

Global( 189)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+8613336195806 sales@capot.com China 29640 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10404 58
Nanjing Dolon Biotechnology Co.,Ltd. 		18905173768 52513593@qq.com CHINA 2972 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29794 58
Richest Group Ltd 		18017061086 oled@richest-group.com CHINA 5600 58
Fuxin Pharmaceutical 		+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10000 58
Neostar United (Changzhou) Industrial Co., Ltd. 		+86-0519-85551759 +8613506123987 marketing1@neostarunited.com China 8828 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
Shenzhen Nexconn Pharmatechs Ltd 		58
Nanjing Dolon Biotechnology Co.,Ltd. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Richest Group Ltd 		58
Fuxin Pharmaceutical 		58
Neostar United (Changzhou) Industrial Co., Ltd. 		58

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View Lastest Price from 2,4,5-Trichlorophenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4,5-Trichlorophenol pictures 2026-04-22 2,4,5-Trichlorophenol
95-95-4
 US $0.00 / kg 20kg 99% 20 tons Qingdao RENAS Polymer Material Co., Ltd.
2,4,5-trichlorophenol pictures 2020-01-15 2,4,5-trichlorophenol
95-95-4
 US $1.00 / g 1g 95-99% 1ton Career Henan Chemical Co

2,4,5-Trichlorophenol Spectrum

2,4,5-Trichlorophenol(95-95-4)MS2,4,5-Trichlorophenol(95-95-4)1HNMR2,4,5-Trichlorophenol(95-95-4)13CNMR2,4,5-Trichlorophenol(95-95-4)IR12,4,5-Trichlorophenol(95-95-4)IR22,4,5-Trichlorophenol(95-95-4)IR32,4,5-Trichlorophenol(95-95-4)Raman

95-95-4(2,4,5-Trichlorophenol)Related Search:

Trichloroacetic acid PHENOLDISULFONIC ACID Sucralose Trichloroethylene Trichlorosilane
2,4-Dichlorophenol 1,3,5-Trichlorobenzene Trichloroisocyanuric acid Chloroform Pentachlorophenol
2,3,4,6-TETRACHLOROPHENOL Pentachlorophenol sodium salt hydrate 2-(2,4,5-TRICHLOROPHENOXY)PROPIONIC ACID 2,3,4,5-TETRACHLOROANISOLE 2,4,5-Trichlorophenoxyacetic acid
Hexachlorophene 2,4,6-Trichlorophenol TETRACHLOROCATECHOL

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