ChemicalBook >> CAS DataBase List >>5-Methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo [2,3-f]indole

5-Methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo [2,3-f]indole

5-Methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo [2,3-f]indole structure

CAS No.: 158942-04-2

Chemical Name:: 5-Methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo [2,3-f]indole

Synonyms: SB 206553;SB 206553 HCL;SB 206553 HYDROCHLORIDE;SB-206553 hydrochloride hydrate;SB-206553 hydrate hydrochloride;1-amino-2-bromo-4-(2-methylanilino)anthracene-9,10-dione;SB 206553 hydrochloride, 5-HT2B and 5-HT2C receptor antagonist;5-Methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo [2,3-f]indole;5-Methyl-N-(pyridin-3-yl)-2,3-dihydropyrrolo[2,3-f]indole-1(5H)-carboxamide;5-METHYL-3,5-DIHYDRO-2H-PYRROLO[2,3-F]INDOLE-1-CARBOXYLIC ACID PYRIDIN-3-YLAMIDE

CBNumber:: CB3726158

Molecular Formula:: C17H16N4O

Molecular Weight:: 292.34

MDL Number:: MFCD00928314

MOL File:: 158942-04-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:52:10

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5-Methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo [2,3-f]indole Properties

Boiling point	575.4±50.0 °C(Predicted)
Density	1.33±0.1 g/cm3(Predicted)
storage temp.	Desiccate at RT
solubility	H₂O: 30 mg/mL
form	solid
pka	13.50±0.20(Predicted)
color	brown
Water Solubility	H2O: >10mg/mL
InChI	1S/C17H16N4O.ClH.H2O/c1-20-7-4-12-10-16-13(9-15(12)20)5-8-21(16)17(22)19-14-3-2-6-18-11-14;;/h2-4,6-7,9-11H,5,8H2,1H3,(H,19,22);1H;1H2
InChIKey	NXGFRKQJHLVHIT-UHFFFAOYSA-N
SMILES	O.Cl.Cn1ccc2cc3N(CCc3cc12)C(=O)Nc4cccnc4
FDA UNII	AL4387525T
UNSPSC Code	12352200
NACRES	NA.77

SAFETY

Risk and Safety Statements

PPE	Eyeshields, Gloves, type N95 (US)
WGK Germany	3
Storage Class	13 - Non Combustible Solids

5-Methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo [2,3-f]indole price More Price(17)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	S180	SB-206553 hydrochloride hydrate ≥98% (HPLC), solid	158942-04-2	25mg	$1230	2022-05-15	Buy
Usbiological	217778	SB 206553 Hydrochloride (5-HT2C Serotonin Receptor Antagonist, SB 206553, 5-HT2B Serotonin Receptor Antagonist, SB 206553, SB206553, SB-206553) ≥99%(HPLC)	158942-04-2	10mg	$566	2026-06-03	Buy
ChemScene	CS-0179860	SB 206553 99.35%	158942-04-2	5mg	$152	2026-06-04	Buy
ChemScene	CS-0179860	SB 206553 99.35%	158942-04-2	10mg	$244	2026-06-04	Buy
ChemScene	CS-0179860	SB 206553 99.35%	158942-04-2	25mg	$515	2026-06-04	Buy

Product number	Packaging	Price	Buy
S180	25mg	$1230	Buy
217778	10mg	$566	Buy
CS-0179860	5mg	$152	Buy
CS-0179860	10mg	$244	Buy
CS-0179860	25mg	$515	Buy

5-Methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo [2,3-f]indole Chemical Properties, Uses, Production

Uses

SB 206553 Hydrochloride is a 5-HT2 antagonist.

Definition

ChEBI: SB 206553 is a pyrroloindole.

Biological Activity

Potent and selective 5-HT 2B /5-HT 2C receptor antagonist (rat 5-HT 2B pA 2 = 8.89, human 5-HT 2C pK i = 7.92). Displays > 80-fold selectivity over all other 5-HT receptor subtypes and a variety of other receptors (pK i < 6). Centrally active following oral administration in vivo .

5-Methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo [2,3-f]indole Preparation Products And Raw materials

Raw materials

Preparation Products

5-Methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo [2,3-f]indole Suppliers

Global Suppliers ( 26)

Supplier	Tel	Email	Country	ProdList	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8435	60
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Suzhou Chenrui Biotechnology Co. LTD	17625585511	1580084073@qq.com	China	991	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	69
EMMX Biotechnology LLC	60
Amadis Chemical Company Limited	58
Suzhou Chenrui Biotechnology Co. LTD	58
TargetMol Chemicals Inc.	58

158942-04-2 (5-Methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo [2,3-f]indole) Related Search:

5-Methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo [2,3-f]indole 5-Aminoindole hydrochloride 5-Amino-1-N-methylindole SB 200646 RARECHEM AN KA 0813

6-Ethylindole

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3,5-DIHYDRO-5-METHYL-N-3-PYRIDINYLBENZO[1,2-B:4,5-B']DIPYRROLE-1(2H)-CARBOXAMIDE HYDROCHLORIDE SB 206553 SB 206553 HYDROCHLORIDE N-3-PYRIDINYL-3,5-DIHYDRO-5-METHYL-BENZO[1,2-B:4,5-B']DIPYRROLE-1(2H)-CARBOXAMIDE HYDROCHLORIDE SB 206553 HCL 5-METHYL-3,5-DIHYDRO-2H-PYRROLO[2,3-F]INDOLE-1-CARBOXYLIC ACID PYRIDIN-3-YLAMIDE 5-methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo[2,3-f]indole hydrochloride N-3-Pyridinyl-3,5-dihydro-5-methylbenzo(1,2-b:4,5-bμ)dipyrrole-1(2H)carboxamide hydrate hydrochloride, 5-Methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo[2,3-f]indole hydrate hydrochloride 1-amino-2-bromo-4-(2-methylanilino)anthracene-9,10-dione SB-206553 hydrate hydrochloride 5-Methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo[2,3-f]indole hydrochloride hydrate N-3-Pyridinyl-3,5-dihydro-5-methylbenzo(1,2-b:4,5-b′)dipyrrole-1(2H)carboxamide hydrochloride hydrate SB-206553 hydrochloride hydrate 5-Methyl-N-(pyridin-3-yl)-2,3-dihydropyrrolo[2,3-f]indole-1(5H)-carboxamide Benzo[1,2-b:4,5-b']dipyrrole-1(2H)-carboxamide, 3,5-dihydro-5-methyl-N-3-pyridinyl- SB 206553 hydrochloride, 5-HT2B and 5-HT2C receptor antagonist 5-Methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo [2,3-f]indole 158942-04-2 C17H16N4OHCl Serotonin receptor pharmacetical