(S)-3-METHYLHEPTANOIC ACID
- CAS No.
- 59614-85-6
- Chemical Name:
- (S)-3-METHYLHEPTANOIC ACID
- Synonyms
- (S)-3-METHYLHEPTANOIC ACID;(3S)-3-Methyl-heptanoic acid;Heptanoic acid,3-methyl-, (3S)-
- CBNumber:
- CB3738337
- Molecular Formula:
- C8H16O2
- Molecular Weight:
- 144.21
- MDL Number:
- MFCD04112705
- MOL File:
- 59614-85-6.mol
| Product description | Number | Pack Size | Price |
| (S)-3-methylheptanoic acid 95% | AA00E8WP | 100mg | $358 |
| (S)-3-methylheptanoic acid 95% | AA00E8WP | 250mg | $653 |
| (S)-3-methylheptanoic acid 95.00% | U109669 | 1G | $1030 |
| (S)-3-methylheptanoic acid 95.00% | U109669 | 5G | $4120 |
| (S)-3-METHYLHEPTANOIC ACID 98.00% | CCH0006149 | 5MG | $503.89 |
| More product size | |||
(S)-3-METHYLHEPTANOIC ACID price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA00E8WP | (S)-3-methylheptanoic acid 95% | 59614-85-6 | 100mg | $358 | 2026-05-28 | Buy |
| aablocks | AA00E8WP | (S)-3-methylheptanoic acid 95% | 59614-85-6 | 250mg | $653 | 2026-05-28 | Buy |
| ACHEMBLOCK | U109669 | (S)-3-methylheptanoic acid 95.00% | 59614-85-6 | 1G | $1030 | 2026-05-27 | Buy |
| ACHEMBLOCK | U109669 | (S)-3-methylheptanoic acid 95.00% | 59614-85-6 | 5G | $4120 | 2026-05-27 | Buy |
| American Custom Chemicals Corporation | CCH0006149 | (S)-3-METHYLHEPTANOIC ACID 98.00% | 59614-85-6 | 5MG | $503.89 | 2021-12-16 | Buy |
(S)-3-METHYLHEPTANOIC ACID Chemical Properties,Uses,Production
Uses
(S)-3-Methylheptanoic acid is a chiral organic acid compound that can be used as a synthetic unit in the synthesis of PGI2 (prostacyclin I2) analogues, such as pimiprost and ronoprost[1].
Synthesis
The synthesis of (S)-3-methylheptanoic acid begins with a chemically selective alkylation reaction between bromo-propylmagnesium and bromoester 3 under Cu(I) catalysis, yielding ester 6 in very high yield. Subsequently, a Barbier–Villain dealkylation reaction was employed to remove an excess carbon atom from 6. Ester 6 reacts with phenylmagnesium bromide to form alcohol 7, which undergoes efficient dehydration in DCM in the presence of a catalytic amount of TMSCl to yield the diphenyl alkene 8. Oxidation of 8 with KMnO₄/NaIO₄ in a t-butanol–water system cleaves the double bond, yielding the target product 1 in 84% yield. Oxidation of 8 with ozone in ethyl acetate, followed by treatment of the resulting mixture with 30% hydrogen peroxide/1.2 mol·L⁻¹ hydrochloric acid, similarly yielded 1 in higher yield. Optically pure compound 1 (91.0% ee) was obtained via its derivative 9.[1]
References
[1] Shunji Zhang, Weisheng T., Yong Shi. (2015). Syntheses of (R)- and (S)-3-Methylheptanoic Acids. Chinese Journal of Chemistry, 33 6, 674–678. https://doi.org/10.1002/cjoc.201400861
(S)-3-METHYLHEPTANOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Benzolyte BCB Technology Co., Ltd | +8618809439555 | benzolyte@139.com | China | 31 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14014 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Changzhou Mascot Import & Export Co., Ltd | +86-0519-85010339 +86-13584504415 | info@mascot-ie.com | China | 435 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| HANGZHOU HAILAN CHEMICAL CO.,LTD. | +86-57156122185 +86-15967590394 | sales@hailan-chem.com | China | 2996 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7891 | 64 |
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