COUMAFURYL
- CAS No.
- 117-52-2
- Chemical Name:
- COUMAFURYL
- Synonyms
- Lurat;Fumasol;Krumkil;Kumatox;Ratafin;Tomarin;FUMARIN;Foumarin;Furmarin;Cumafuryl
- CBNumber:
- CB3743658
- Molecular Formula:
- C17H14O5
- Molecular Weight:
- 298.29
- MDL Number:
- MFCD00128012
- MOL File:
- 117-52-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 124° |
|---|---|
| Boiling point | 359.71°C (rough estimate) |
| Density | 1.2006 (rough estimate) |
| refractive index | 1.6200 (estimate) |
| Flash point | >212 °C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 4.50±1.00(Predicted) |
| color | White |
| Merck | 13,2582 |
| BRN | 6817711 |
| Major Application |
agriculture environmental |
| InChI | 1S/C17H14O5/c1-10(18)9-12(13-7-4-8-21-13)15-16(19)11-5-2-3-6-14(11)22-17(15)20/h2-8,12,19H,9H2,1H3 |
| InChIKey | JFIXKFSJCQNGEK-UHFFFAOYSA-N |
| SMILES | CC(=O)CC(c1ccco1)C2=C(O)c3ccccc3OC2=O |
| EWG's Food Scores | 1 |
| FDA UNII | 7ELL4M4VS8 |
| EPA Substance Registry System | Coumafuryl (117-52-2) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H300-H372-H412 |
| Precautionary statements | P260-P264-P270-P273-P301+P310-P314 |
| PPE | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
| Hazard Codes | T |
| Risk Statements | 25-48/25-52/53 |
| Safety Statements | 37-45-61 |
| RIDADR | 3027 |
| WGK Germany | 3 |
| RTECS | GN4850000 |
| HazardClass | 6.1(a) |
| PackingGroup | II |
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
| Hazard Classifications | Acute Tox. 2 Oral Aquatic Chronic 3 STOT RE 1 Oral |
| Hazardous Substances Data | 117-52-2(Hazardous Substances Data) |
| Toxicity | LDLo orl-rat: 400 mg/kg 85GYAZ -,115,71 |
COUMAFURYL price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 34324 | Coumafuryl PESTANAL , analytical standard | 117-52-2 | 50mg | $93 | 2022-05-15 | Buy |
| TRC | TRC-C765603-50MG | Coumafuryl | 117-52-2 | 50mg | $706 | 2026-06-03 | Buy |
| TRC | TRC-C765603-2.5MG | Coumafuryl | 117-52-2 | 2.5mg | $89 | 2026-06-03 | Buy |
| TRC | TRC-C765603-10MG | Coumafuryl | 117-52-2 | 10mg | $184 | 2026-06-03 | Buy |
| ChemScene | CS-0081297 | Coumafuryl | 117-52-2 | 2.5mg | $194 | 2026-06-04 | Buy |
COUMAFURYL Chemical Properties, Uses, Production
Description
Coumafuryl is an obsolete anticoagulant rodenticide. It is moderately soluble in water and is not volatile. Data suggests it is mobile and so it may have potential to leach to groundwater but its pattern of use would tend to significantly reduce the risk. Little is known about its toxicity to biodiversity. It is highly toxic to mammals via the oral route.
Chemical Properties
Coumafuryl is a colorless, white, crystalline solid or powder.
Uses
Rodenticide.
Production Methods
Coumafuryl is commercially produced through a condensation reaction between 4-hydroxycoumarin and 2-furylmethyl ketone. This synthesis typically occurs in the presence of a base such as sodium hydroxide and a solvent like ethanol or acetic acid, under controlled temperature conditions to facilitate the formation of the desired compound. After the reaction, the product is purified through crystallisation and drying to yield a white to off-white powder.
Definition
ChEBI: Coumafuryl is a hydroxycoumarin.
Mechanism of action
Anticoagulant - interferes with the production of blood clotting factors in the liver by blocking the action of vitamin K
Safety Profile
Poison by ingestion and possiblyother routes.
Potential Exposure
This material is an anticoagulant rodenticide. Therefore, those involved in its manufacture, formulation, and application are at risk.
Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3027 Coumarin derivative pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials
Incompatibilities
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. At room temperature this material can decompose rapidly to cobalt carbonyl and hydrogen gas; at 52°C cobalt carbonyl decomposes, producing toxic fumes of cobalt and oxides of carbon
Pesticide Type
Rodenticide
