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ChemicalBook >> CAS DataBase List >>Benzoic acid, 3-[2-[(2-fluorophenyl)amino]-5-oxazolyl]-

Benzoic acid, 3-[2-[(2-fluorophenyl)amino]-5-oxazolyl]-

Benzoic acid, 3-[2-[(2-fluorophenyl)amino]-5-oxazolyl]- Structure
Benzoic acid, 3-[2-[(2-fluorophenyl)amino]-5-oxazolyl]- structure
CAS No.
2375281-44-8
Chemical Name:
Benzoic acid, 3-[2-[(2-fluorophenyl)amino]-5-oxazolyl]-
Synonyms
NF-κΒ activator 2;NF-κΒ activator 2, 10 mM in DMSO;3-[2-(2-fluoroanilino)-1,3-oxazol-5-yl]benzoic acid;3-(2-((2-Fluorophenyl)amino)oxazol-5-yl)benzoic acid;Benzoic acid, 3-[2-[(2-fluorophenyl)amino]-5-oxazolyl]-;3-{2-[(2-fluorophenyl)amino]-1,3-oxazol-5-yl}benzoic acid;Nuclear factor-kappaB,NF-κΒ activator 2,NF-κB,ALS,amyotrophic,Nuclear factor-κB,lateral,NF κΒ activator 2,NFκΒ activator 2,NF-?B,Inhibitor,SOD2,sclerosis,inhibit
CBNumber:
CB38201051
Molecular Formula:
C16H11FN2O3
Molecular Weight:
298.27
MDL Number:
MOL File:
2375281-44-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-11 16:31:51
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Benzoic acid, 3-[2-[(2-fluorophenyl)amino]-5-oxazolyl]- Properties

Boiling point 512.1±60.0 °C(Predicted)
Density 1.396±0.06 g/cm3(Predicted)
pka 3.89±0.10(Predicted)
form Solid
color White to off-white

Benzoic acid, 3-[2-[(2-fluorophenyl)amino]-5-oxazolyl]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0142823 NF-κΒ activator 2 99.76% 2375281-44-8 5mg $310 2026-06-04 Buy
ChemScene CS-0142823 NF-κΒ activator 2 99.76% 2375281-44-8 10mg $459 2026-06-04 Buy
ChemScene CS-0142823 NF-κΒ activator 2 99.76% 2375281-44-8 25mg $737 2026-06-04 Buy
ChemScene CS-0142823 NF-κΒ activator 2 99.76% 2375281-44-8 50mg $999 2026-06-04 Buy
ChemScene CS-0142823 NF-κΒ activator 2 99.76% 2375281-44-8 100mg $1283 2026-06-04 Buy
Product number Packaging Price Buy
CS-0142823 5mg $310 Buy
CS-0142823 10mg $459 Buy
CS-0142823 25mg $737 Buy
CS-0142823 50mg $999 Buy
CS-0142823 100mg $1283 Buy

Benzoic acid, 3-[2-[(2-fluorophenyl)amino]-5-oxazolyl]- Chemical Properties, Uses, Production

Uses

NF-κΒ activator 2 is a potent and orally active NF-B activator, with an EC50 of 1.58 μM. NF-κΒ activator 2 induces SOD2 through increasing NF-B expression and activation. NF-κΒ activator 2 can be used for the research of amyotrophic lateral sclerosis (ALS)[1].

in vivo

NF-κΒ activator 2 (1 mg/kg; i.v.) displays a suitable half-life (0.96 h) in mice[1].
NF-κΒ activator 2 (5 mg/kg; p.o.) displays a comparable half-life (2.86 h), oral bioavailability (15.6%), and Cmax (92 ng/mL)[1].

IC 50

NF-κB: 1.58 μM (EC50)

References

[1] Mathew B, et, al. Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-B activators for the treatment of ALS. Eur J Med Chem. 2020 Oct 22;112952. DOI:10.1016/j.ejmech.2020.112952

Benzoic acid, 3-[2-[(2-fluorophenyl)amino]-5-oxazolyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzoic acid, 3-[2-[(2-fluorophenyl)amino]-5-oxazolyl]- Suppliers

Global Suppliers ( 29)
Supplier Tel Email Country ProdList Advantage
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4860 55
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2996 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Changzhou Chenhong Biotechnology Co., Ltd. +86-0519-85788828 +86-13775037613 sales@chemrenpharm.com China 4058 58
Wuhan chuang he chemical co. LTD 15907120073 1261789306@qq.com China 1358 58
Hefei fuya biotechnology co. LTD 18096409024 sales02@foreversyn.com China 1934 58
Zhejiang Huida Biotech Co., LTD 0571-89903022 18679456698 zilong@hizyme.com China 8001 58
Supplier Advantage
BOC Sciences 65
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai Beckham Medical Technology Co., Ltd 55
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
TargetMol Chemicals Inc. 58
Changzhou Chenhong Biotechnology Co., Ltd. 58
Wuhan chuang he chemical co. LTD 58
Hefei fuya biotechnology co. LTD 58
Zhejiang Huida Biotech Co., LTD 58

View Latest Price from Benzoic acid, 3-[2-[(2-fluorophenyl)amino]-5-oxazolyl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
NF-κΒ activator 2 pictures 2026-05-11 NF-κΒ activator 2
2375281-44-8
 $95.00-238.00 99.32% 10g TargetMol Chemicals Inc.

Benzoic acid, 3-[2-[(2-fluorophenyl)amino]-5-oxazolyl]- Spectrum

Benzoic acid, 3-[2-[(2-fluorophenyl)amino]-5-oxazolyl]-(2375281-44-8)1HNMR

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Benzoic acid, 3-[2-[(2-fluorophenyl)amino]-5-oxazolyl]- NF-κΒ activator 2 3-(2-((2-Fluorophenyl)amino)oxazol-5-yl)benzoic acid Nuclear factor-kappaB,NF-κΒ activator 2,NF-κB,ALS,amyotrophic,Nuclear factor-κB,lateral,NF κΒ activator 2,NFκΒ activator 2,NF-?B,Inhibitor,SOD2,sclerosis,inhibit 3-{2-[(2-fluorophenyl)amino]-1,3-oxazol-5-yl}benzoic acid NF-κΒ activator 2, 10 mM in DMSO 3-[2-(2-fluoroanilino)-1,3-oxazol-5-yl]benzoic acid 2375281-44-8