4-(5-Hydroxymethylimidazol-1-ylmethyl)benzonitrile
- CAS No.
- 183500-36-9
- Chemical Name:
- 4-(5-Hydroxymethylimidazol-1-ylmethyl)benzonitrile
- Synonyms
- CYP19A1/CYP11B2-IN-1;4-(5-Hydroxymethylimidazol-1-ylmethyl)benzonitrile
- CBNumber:
- CB3846764
- Molecular Formula:
- C12H11N3O
- Molecular Weight:
- 213.23524
- MDL Number:
- MFCD08668150
- MOL File:
- 183500-36-9.mol
- MSDS File:
- SDS
4-(5-Hydroxymethylimidazol-1-ylmethyl)benzonitrile price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0908768 | CYP19A1/CYP11B2-IN-1 99.85% | 183500-36-9 | 5mg | $238 | 2026-06-04 | Buy |
| ChemScene | CS-0908768 | CYP19A1/CYP11B2-IN-1 99.85% | 183500-36-9 | 10mg | $379 | 2026-06-04 | Buy |
| ChemScene | CS-0908768 | CYP19A1/CYP11B2-IN-1 99.85% | 183500-36-9 | 25mg | $758 | 2026-06-04 | Buy |
| ChemScene | CS-0908768 | CYP19A1/CYP11B2-IN-1 99.85% | 183500-36-9 | 50mg | $1246 | 2026-06-04 | Buy |
| ChemScene | CS-0908768 | CYP19A1/CYP11B2-IN-1 99.85% | 183500-36-9 | 100mg | $2004 | 2026-06-04 | Buy |
4-(5-Hydroxymethylimidazol-1-ylmethyl)benzonitrile Chemical Properties, Uses, Production
Uses
CYP19A1/CYP11B2-IN-1 (Compound X21) is a potent and selective aromatase and aldosterone synthase dual inhibitor with IC50s of 2.3 nM and 29 nM for aromatase (CYP19A1) and aldosterone synthase (CYP11B2), respectively. CYP19A1/CYP11B2-IN-1 has excellent antiproliferative and pro-apoptotic activity against the cancer cell. CYP19A1/CYP11B2-IN-1 can be used for research of breast cancer[1].
References
[1] Tinivella A, et al. Discovery of a Potent Dual Inhibitor of Aromatase and Aldosterone Synthase. ACS Pharmacology & Translational Science. 2023 Nov 23. DOI:10.1021/acsptsci.3c00183
4-(5-Hydroxymethylimidazol-1-ylmethyl)benzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
4-(5-Hydroxymethylimidazol-1-ylmethyl)benzonitrile Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Territorial sea Biological Technology Co., LTD | 15092083467 | tangfenjiushililiang@leadhigh.com.cn | China | 2986 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 4999 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| Shandong Territorial sea Biological Technology Co., LTD | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
