Pexiganan
- CAS No.
- 172820-23-4
- Chemical Name:
- Pexiganan
- Synonyms
- Pexiganan;Pexiganan (MSI-78)
- CBNumber:
- CB41116537
- Molecular Formula:
- C124H214N32O24
- Molecular Weight:
- 2537.28
- MDL Number:
- MOL File:
- 172820-23-4.mol
| storage temp. | Store at -20°C |
|---|---|
| solubility | DMF: Slightly soluble,DMSO: Slightly soluble,Ethanol: 12 mg/ml,PBS (pH 7.2): 5 mg/ml |
| form | A solid |
| color | white to off-white |
| Sequence | H-Gly-Ile-Gly-Lys-Phe-Leu-Lys-Lys-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Lys-Leu-Leu-Lys-Lys-NH2 |
| FDA UNII | 63S35FF5KS |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
Pexiganan Chemical Properties,Uses,Production
Uses
Treatment of diabetic foot ulcer infections (antibacterial).
brand name
Cytolex (Abbott).
Biological Activity
Pexiganan (MSI-78) is a 22-aa synthetic cationic antimicrobial peptide (AMP), an analog of magainin found in the African clawed frog (Xenopus laevis). Pexiganan is effective against both Gram-positive (staphylococci MIC ≤16 μg/mL, streptococci & methicillin-resistant S. aureus MIC 8-64 μg/mL, S. pyrogenes MIC 16-256 μg/mL) and Gram-negative aerobes (MIC 4-32 μg/mL, E. cloacae MCI 1-128 μg/mL, A. faecalis 4-64 μg/mL) by disrupting bacteria cell wall or membrane.
Pexiganan Preparation Products And Raw materials
Raw materials
Preparation Products
Pexiganan Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 10997 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| Hangzhou Go Top Peptide Biotech | 0571-88211921 | sales1@gotopbio.com | CHINA | 2609 | 58 |
| Hebei Miaoyin Technology Co.,Ltd | +852-852-95427495 +85295427495 | kathy@hbyinsheng.com | China | 3512 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43339 | 58 |
| Hubei KDG Web Science&Technology Co., Ltd | 18672314556 +8618672314556 | sales@kdg-tech.com | China | 933 | 58 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 15178 | 58 |
| Creative Peptides | info@creative-peptides.com | United States | 6083 | 56 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
