4-Amino-3,5-diiodopyridine
- CAS No.
- 98136-86-8
- Chemical Name:
- 4-Amino-3,5-diiodopyridine
- Synonyms
- 3,5-Diiodopyridin-4-amine;3,5-diiodo-4-aminopyridine;3,4-diiodo-4-aminopyridine;4-Amino-3,5-diiodopyridine;4-Pyridinamine, 3,5-diiodo-;Pyridine,4-aMino-3,5-diiodo-;4-AMINO-3,5-DIIODOPYRIDINE ISO 9001：2015 REACH
- CBNumber:
- CB4129112
- Molecular Formula:
- C5H4I2N2
- Molecular Weight:
- 345.91
- MDL Number:
- MFCD02663851
- MOL File:
- 98136-86-8.mol
- MSDS File:
- SDS
| Melting point | 135-136℃ |
|---|---|
| Boiling point | 408.1±45.0 °C(Predicted) |
| Density | 2.679 |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 5.42±0.24(Predicted) |
| form | solid |
| Appearance | White to off-white Solid |
| InChI | 1S/C5H4I2N2/c6-3-1-9-2-4(7)5(3)8/h1-2H,(H2,8,9) |
| InChIKey | XDDQGODHCQZZEH-UHFFFAOYSA-N |
| SMILES | IC1=CN=CC(I)=C1N |
| UNSPSC Code | 12352116 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xi,Xn |
| Risk Statements | 22 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| HS Code | 2933399990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral |
4-Amino-3,5-diiodopyridine price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | VBP00076 | 3,5-Diiodopyridin-4-amine Aldrich | 98136-86-8 | 1g | $191 | 2026-04-30 | Buy |
| Apolloscientific | OR9959 | 4-Amino-3,5-diiodopyridine ≥95% | 98136-86-8 | 1g | $22 | 2026-06-04 | Buy |
| Apolloscientific | OR9959 | 4-Amino-3,5-diiodopyridine ≥95% | 98136-86-8 | 5g | $82 | 2026-06-04 | Buy |
| Apolloscientific | OR9959 | 4-Amino-3,5-diiodopyridine ≥95% | 98136-86-8 | 10g | $146 | 2026-06-04 | Buy |
| Activate Scientific | AS22238 | 4-Amino-3,5-diiodopyridine 97% | 98136-86-8 | 1g | $68 | 2026-06-04 | Buy |
4-Amino-3,5-diiodopyridine Chemical Properties, Uses, Production
Synthesis
504-24-5
98136-86-8
General procedure for the synthesis of 3,5-diiodo-4-aminopyridine from 4-aminopyridine: 500 mL of methanol, 3000 mL of water, 94.11 g (1.0 mol) of 4-aminopyridine, 224.10 g (1.35 mol) of potassium iodide, and 149.80 g (0.70 mol) of potassium iodate were added sequentially to the reaction flask. 160 mL of hydrochloric acid was slowly added dropwise with controlled titration rate, and the titration process lasted for 3 hours. After the dropwise addition, the reaction was continued for 1 hour. Subsequently, 50 mL of an aqueous solution containing 17.73 g (0.20 mol) of sodium chlorite was added dropwise. After the dropwise addition was completed, the reaction process was monitored by HPLC and the reaction was continued for 0.5 hours. Upon completion of the reaction, the reaction solution was diluted with 4000 mL of water, and then 6000 mg of trichloromethane was added in three portions as an extractant. The organic phase was washed sequentially with an aqueous solution containing sodium thiosulfate and an aqueous solution of sodium bicarbonate, separated and dried with anhydrous magnesium sulfate. The solvent was removed by concentration under reduced pressure to give the crude product of 3,5-diiodo-4-aminopyridine in gray color. The crude product was recrystallized with a mixed solvent of ethanol and water to give 318.23 g of white crystalline solid in 92.0% yield.
References
[1] Patent: CN104262242, 2016, B. Location in patent: Paragraph 0030; 0031
[2] Tetrahedron Letters, 2007, vol. 48, # 11, p. 1983 - 1986
4-Amino-3,5-diiodopyridine Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Chengdu Forest Science and Technology Development Co., Ltd. | 18030648795 18030648795 | sales@cdforestchem.com | China | 1998 | 58 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3996 | 55 |
| Shijiazhuang suchen Chemical Technology Co. LTD | 186-33933494 18032288352 | 1130239@qq.com | China | 192 | 60 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 | |
| Shanghai Yolne Chemical Co., Ltd. | 021-62960152 | 934678158@qq.com | China | 9886 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Yongye Biotechnology Co., Ltd. | 86-021-61559134 15921386130 | 3423497944@qq.com | China | 8135 | 55 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
| Bellen Chemistry Co., Ltd. | 010-60400365-8001 15910885229 | service@bellenchem.com | China | 4514 | 60 |
View Latest Price from 4-Amino-3,5-diiodopyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 4-AMINO-3,5-DIIODOPYRIDINE
98136-86-8
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2019-12-26 | 4-AMINO-3,5-DIIODOPYRIDINE
98136-86-8
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 4-AMINO-3,5-DIIODOPYRIDINE
98136-86-8
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 4-AMINO-3,5-DIIODOPYRIDINE
98136-86-8
- $1.00
- 99%
- Career Henan Chemical Co
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