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4-Hydroxy-2,6-dimethylpyridine

4-Hydroxy-2,6-dimethylpyridine structure

CAS No.: 13603-44-6

Chemical Name:: 4-Hydroxy-2,6-dimethylpyridine

Synonyms: 2,6-Dimethyl-4-pyridinol;2,6-DIMETHYL-PYRIDIN-4-OL;2,6-Dimethylpyridine-4-ol;4-PYRIDINOL, 2,6-DIMETHYL-;4-HYDROXY-2,6-DIMETHYLPYRIDINE;2,6-DIMETHYL-4-HYDROXYPYRIDINE;2,6-Dimethyl-4-hydroxypyridine>2,6-Dimethyl-4-hydroxypyridine 98%;2,6- two methyl -4- hydroxypyridine;2,6-Dimethyl-4-hydroxypyridine ,98%

CBNumber:: CB2345053

Molecular Formula:: C7H9NO

Molecular Weight:: 123.15

MDL Number:: MFCD00956021

MOL File:: 13603-44-6.mol

MSDS File:: SDS

Last updated:2026-04-21 10:31:43

Product description	Number	Pack Size	Price
2,6-Dimethyl-4-hydroxypyridine >98.0%(GC)	D3638	1g	$34
2,6-Dimethyl-4-hydroxypyridine >98.0%(GC)	D3638	5g	$168
2,6-Dimethyl-4-hydroxypyridine	D473270	2.5g	$110
2,6-Dimethyl-4-hydroxypyridine	D473270	25g	$300
2,6-Dimethyl-4-hydroxypyridine 98%	JK190019	5g	$310
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4-Hydroxy-2,6-dimethylpyridine Properties

Melting point	230-232°C
Boiling point	351 °C
Density	1,053g/cm
refractive index	1,501-1,503
storage temp.	Inert atmosphere,Room Temperature
solubility	DMSO (Slightly, Heated), Methanol (Slightly)
pka	5.49±0.23(Predicted)
form	Solid
color	White to Off-White
InChI	InChI=1S/C7H9NO/c1-5-3-7(9)4-6(2)8-5/h3-4H,1-2H3,(H,8,9)
InChIKey	PRAFLUMTYHBEHE-UHFFFAOYSA-N
SMILES	C1(C)=NC(C)=CC(O)=C1
LogP	0.190 (est)
CAS DataBase Reference	13603-44-6(CAS DataBase Reference)
FDA UNII	92JKJ9S198

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-36/37/39

HazardClass

IRRITANT

HS Code

29333990

NFPA 704

	0
1		0

4-Hydroxy-2,6-dimethylpyridine price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	D3638	2,6-Dimethyl-4-hydroxypyridine >98.0%(GC)	13603-44-6	1g	$34	2026-03-19	Buy
TCI Chemical	D3638	2,6-Dimethyl-4-hydroxypyridine >98.0%(GC)	13603-44-6	5g	$168	2026-03-19	Buy
TRC	D473270	2,6-Dimethyl-4-hydroxypyridine	13603-44-6	2.5g	$110	2021-12-16	Buy
TRC	D473270	2,6-Dimethyl-4-hydroxypyridine	13603-44-6	25g	$300	2021-12-16	Buy
Frontier Specialty Chemicals	JK190019	2,6-Dimethyl-4-hydroxypyridine 98%	13603-44-6	5g	$310	2021-12-16	Buy

Product number	Packaging	Price	Buy
D3638	1g	$34	Buy
D3638	5g	$168	Buy
D473270	2.5g	$110	Buy
D473270	25g	$300	Buy
JK190019	5g	$310	Buy

4-Hydroxy-2,6-dimethylpyridine Chemical Properties,Uses,Production

Chemical Properties

Yellow to Brown Cryst

Uses

2,6-Dimethyl-4-hydroxypyridine is a useful synthetic intermediate. It is used in the synthesis of disubstituted pyridinyl-aminohydantoins as selective human BACE1 inhibitors.

Synthesis

520-45-6

13603-44-6

The general procedure for the synthesis of 2,6-dimethyl-4-hydroxypyridine from dehydroacetic acid was as follows: five different batches of dehydroacetic acid (1.5 g, 8.92 mmol) were suspended in concentrated ammonia (4 mL) and placed in a microwave reactor (Discover system, 150 W, CEM Corporation, Matthews, North Carolina, USA) and microwave irradiated at 120°C for 20 min. Upon completion of the reaction, the reaction mixture was cooled and all batches were combined and subsequently evaporated to dryness to afford the target product 2,6-dimethyl-4-hydroxypyridine. The mass of the product was 5.91 g (108% yield), which was analyzed by LC/MS showing a purity of 73%. Unreacted dehydroacetic acid was present as a residual mass balance.The LC/MS retention time was 0.67 min and the mass spectrum (ES+) showed m/z 168 (M + CH3CN + H).

References

[1] Patent: WO2008/57497, 2008, A2. Location in patent: Page/Page column 252-253
[2] Patent: WO2008/57469, 2008, A1. Location in patent: Page/Page column 252-253
[3] Patent: WO2008/57468, 2008, A1. Location in patent: Page/Page column 252-253
[4] Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1988, vol. 42, # 6, p. 373 - 377
[5] Chemische Berichte, 1887, vol. 20, p. 159

4-Hydroxy-2,6-dimethylpyridine Preparation Products And Raw materials

Raw materials

Sodium nitrite 2,6-DIMETHYL-PYRIDIN-4-YLAMINE Sulfuric acid Dehydroacetic acid Ammonia

Preparation Products

2,6-DIMETHYL-PYRIDIN-4-YLAMINE Clopidol 4-Hydroxypyridine-2,6-dicarboxylic acid N,N-Dimethylcarbamic acid 2,6-dimethyl-4-pyridyl ester

4-Hydroxy-2,6-dimethylpyridine Suppliers

Global( 228)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Fluoropharm Co., Ltd.	+86-0571-85586753 +86-13336034509	sales@fluoropharm.com	China	1445	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29821	58
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2994	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10404	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Fluoropharm Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58
Changzhou Ansciep Chemical Co., Ltd.	58
Shenzhen Nexconn Pharmatechs Ltd	58
Alchem Pharmtech,Inc.	58

View Lastest Price from 4-Hydroxy-2,6-dimethylpyridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-20	4-Hydroxy-2,6-dimethylpyridine 13603-44-6	US $0.00-0.00 / mg			10g	TargetMol Chemicals Inc.
2026-03-20	4-Hydroxy-2,6-dimethylpyridine 13603-44-6	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-11-18	4-Hydroxy-2,6-dimethylpyridine 13603-44-6	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited

4-Hydroxy-2,6-dimethylpyridine
13603-44-6
US $0.00-0.00 / mg
TargetMol Chemicals Inc.

4-Hydroxy-2,6-dimethylpyridine
13603-44-6
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

4-Hydroxy-2,6-dimethylpyridine
13603-44-6
US $1.10 / g
99.00%
Dideu Industries Group Limited

4-Hydroxy-2,6-dimethylpyridine Spectrum

4-Hydroxy-2,6-dimethylpyridine(13603-44-6)¹HNMR 4-Hydroxy-2,6-dimethylpyridine(13603-44-6)FT-IR

13603-44-6(4-Hydroxy-2,6-dimethylpyridine)Related Search:

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4-[2,6-BIS(TRIFLUOROMETHYL)PYRIDIN-4-YLOXY]ANILINE 5,8-DIHYDRO-4,6-DIHYDROXY-5,8-DIOXO-2-QUINOLINECARBOXYLIC ACID 4'-ETHOXY-2,2':6',2''-TERPYRIDINE

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2,6-DIMETHYL-PYRIDIN-4-OL 2,6-DIMETHYL-4-HYDROXYPYRIDINE 2,6-Dimethyl-4-hydroxypyridine 98% 2,6-Dimethyl-4-pyridinol 2,6-Dimethyl-4-hydroxypyridine ,98% 2,6-Dimethylpyridine-4-ol 2,6-Dimethylpyridin-4-ol, 4-Hydroxy-2,6-lutidine 4-HYDROXY-2,6-DIMETHYLPYRIDINE 4-PYRIDINOL, 2,6-DIMETHYL- 2,6- two methyl -4- hydroxypyridine 2,6-Dimethyl-4-hydroxypyridine> 4-Hydroxy-2,6-dimethylpyridine ISO 9001：2015 REACH 13603-44-6 13603-44-5 Heterocycle-Pyridine series Heterocyclic Building Blocks pharmacetical Pyridine Pyridines derivates Heterocyclic Compounds Pyridines