ChemicalBook >> CAS DataBase List >>1H-Indole-2-carboxamide, N-[3-(2-amino-1H-imidazol-5-yl)phenyl]-5-(trifluoromethoxy)-, hydrochloride (1:1)

1H-Indole-2-carboxamide, N-[3-(2-amino-1H-imidazol-5-yl)phenyl]-5-(trifluoromethoxy)-, hydrochloride (1:1)

1H-Indole-2-carboxamide, N-[3-(2-amino-1H-imidazol-5-yl)phenyl]-5-(trifluoromethoxy)-, hydrochloride (1:1) structure

CAS No.: 1609461-57-5

Chemical Name:: 1H-Indole-2-carboxamide, N-[3-(2-amino-1H-imidazol-5-yl)phenyl]-5-(trifluoromethoxy)-, hydrochloride (1:1)

Synonyms: HV1-IN-1 hydrochloride;1H-Indole-2-carboxamide, N-[3-(2-amino-1H-imidazol-5-yl)phenyl]-5-(trifluoromethoxy)-, hydrochloride (1:1)

CBNumber:: CB414686397

Molecular Formula:: C19H14F3N5O2.ClH

Molecular Weight:: 437.8

MDL Number:

MOL File:: 1609461-57-5.mol

Last updated:2025-04-18 09:52:16

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1H-Indole-2-carboxamide, N-[3-(2-amino-1H-imidazol-5-yl)phenyl]-5-(trifluoromethoxy)-, hydrochloride (1:1) Chemical Properties, Uses, Production

Uses

HV1-IN-1 hydrochloride is an inhibitor of the human voltage-gated proton channel (hHV1). HV1-IN-1 hydrochloride works by binding to the VSD of the HV1 channel. The VSD is a component of the HV1 channel that is responsible for detecting changes in membrane potential and triggering the opening of the channel. HV1-IN-1 hydrochloride can be used in the study of cancer, neuroinflammation and immune response[1].

References

[1] Piga M, et al. Identification of a Novel Structural Class of HV1 Inhibitors by Structure-Based Virtual Screening[J]. Journal of Chemical Information and Modeling, 2024. DOI:10.1021/acs.jcim.4c00240

1H-Indole-2-carboxamide, N-[3-(2-amino-1H-imidazol-5-yl)phenyl]-5-(trifluoromethoxy)-, hydrochloride (1:1) Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Indole-2-carboxamide, N-[3-(2-amino-1H-imidazol-5-yl)phenyl]-5-(trifluoromethoxy)-, hydrochloride (1:1) Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

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1H-Indole-2-carboxamide, N-[3-(2-amino-1H-imidazol-5-yl)phenyl]-5-(trifluoromethoxy)-, hydrochloride (1:1) HV1-IN-1 hydrochloride 1609461-57-5