ChemicalBook >> CAS DataBase List >>1-(4-Trifluoromethylpyrimidin-2-yl)piperazine

1-(4-Trifluoromethylpyrimidin-2-yl)piperazine

1-(4-Trifluoromethylpyrimidin-2-yl)piperazine structure

CAS No.: 179756-91-3

Chemical Name:: 1-(4-Trifluoromethylpyrimidin-2-yl)piperazine

Synonyms: 2-PIPERAZIN-YL-4-(TRIFLUOROMETHYL)PYRIMIDINE;1-(4-Trifluoromethylpyrimidin-2-yl)piperazine;2-(1-Piperazinyl)-4-(trifluoromethyl)pyrimidine;2-(Piperazin-1-yl)-4-(trifluoromethyl)pyrimidine;1-[4-(Trifluoromethyl)pyrimid-2-yl]piperazine ,97%;Pyrimidine, 2-(1-piperazinyl)-4-(trifluoromethyl)-;1-[4-(TrifluoroMethyl)-2-pyriMidinyl]piperazine, 97%;1-(4-Trifluoromethylpyrimidin-2-yl)piperazine ISO 9001：2015 REACH

CBNumber:: CB41471012

Molecular Formula:: C9H11F3N4

Molecular Weight:: 232.21

MDL Number:: MFCD00203912

MOL File:: 179756-91-3.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:45

Product description	Number	Pack Size	Price
2-(Piperazin-1-yl)-4-(trifluoromethyl)pyrimidine	P482505	50mg	$60
1-(4-TRIFLUOROMETHYLPYRIMIDIN-2-YL)PIPERAZINE 95.00%	CHM0000799	1G	$808.89
1-(4-TRIFLUOROMETHYLPYRIMIDIN-2-YL)PIPERAZINE 95.00%	CHM0000799	2.5G	$1147.43
2-Piperazin-1-yl-4-(trifluoromethyl)pyrimidine 97%	085434	10g	$1344
1-(4-TRIFLUOROMETHYLPYRIMIDIN-2-YL)PIPERAZINE 95.00%	CHM0000799	5G	$1421.65
More product size

Request For Quotation

1-(4-Trifluoromethylpyrimidin-2-yl)piperazine Properties

Melting point	50-52°C
Boiling point	331.3±52.0 °C(Predicted)
Density	1.306±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	8.56±0.10(Predicted)
Appearance	White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P305+P351+P338

Hazard Codes

HS Code

29335990

NFPA 704

	1
3		0

1-(4-Trifluoromethylpyrimidin-2-yl)piperazine price More Price(17)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	P482505	2-(Piperazin-1-yl)-4-(trifluoromethyl)pyrimidine	179756-91-3	50mg	$60	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0000799	1-(4-TRIFLUOROMETHYLPYRIMIDIN-2-YL)PIPERAZINE 95.00%	179756-91-3	1G	$808.89	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0000799	1-(4-TRIFLUOROMETHYLPYRIMIDIN-2-YL)PIPERAZINE 95.00%	179756-91-3	2.5G	$1147.43	2021-12-16	Buy
Matrix Scientific	085434	2-Piperazin-1-yl-4-(trifluoromethyl)pyrimidine 97%	179756-91-3	10g	$1344	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0000799	1-(4-TRIFLUOROMETHYLPYRIMIDIN-2-YL)PIPERAZINE 95.00%	179756-91-3	5G	$1421.65	2021-12-16	Buy

Product number	Packaging	Price	Buy
P482505	50mg	$60	Buy
CHM0000799	1G	$808.89	Buy
CHM0000799	2.5G	$1147.43	Buy
085434	10g	$1344	Buy
CHM0000799	5G	$1421.65	Buy

1-(4-Trifluoromethylpyrimidin-2-yl)piperazine Chemical Properties,Uses,Production

Chemical Properties

Gray solid

Synthesis

110-85-0

33034-67-2

1-(4-Trifluoromethylpyrimidin-2-yl)piperazine

179756-91-3

2-Chloro-4-trifluoromethylpyrimidine (2.0 g, 11 mmol) and piperazine (2.8 g, 33 mmol) were dissolved in DMF (10 mL) and triethylamine (3.0 mL, 22 mmol) was added as base. The reaction mixture was placed in a sealed tube and the reaction was stirred at 100 °C overnight. After completion of the reaction, most of the solvent was removed under reduced pressure. The crude product was purified by silica gel column chromatography with EtOAc to EtOAc/MeOH/NEt3 (9:1:0.5) as eluent to afford 1-(4-trifluoromethylpyrimidin-2-yl)piperazine (1.48 g, 56% yield). Mass spectrometry analysis: the calculated value (M+H) of C9H11F3N4 was 233 and the measured value was 233.1.

References

[1] Patent: US2006/4018, 2006, A1. Location in patent: Page/Page column 37

1-(4-Trifluoromethylpyrimidin-2-yl)piperazine Preparation Products And Raw materials

Raw materials

Piperazine 2-Chloro-4-(trifluoromethyl)pyrimidine Triethylamine N,N-Dimethylformamide

Preparation Products

1-(4-Trifluoromethylpyrimidin-2-yl)piperazine Suppliers

Global( 85)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29822	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
Shanghai Rlavie Technology Co ltd	+86-021-67759270 +8617717059219	sales@rlavie.com	China	1030	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	18895	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58

Supplier	Advantage
career henan chemical co	58
Changzhou Ansciep Chemical Co., Ltd.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
SIMAGCHEM CORP	58
Shanghai Rlavie Technology Co ltd	58
Dideu Industries Group Limited	58
Hefei Hirisun Pharmatech Co., Ltd	58

View Lastest Price from 1-(4-Trifluoromethylpyrimidin-2-yl)piperazine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-18	1-(4-Trifluoromethylpyrimidin-2-yl)piperazine 179756-91-3	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2022-04-22	1-(4-Trifluoromethylpyrimidin-2-yl)piperazine 179756-91-3	US $0.00 / KG	0.0001KG	98%min	100kgs/month	Shanghai Rlavie Technology Co ltd
2019-07-06	1-(4-Trifluoromethylpyrimidin-2-yl)piperazine 179756-91-3	US $1.00 / kg	1kg	98%	200kg	Career Henan Chemical Co

1-(4-Trifluoromethylpyrimidin-2-yl)piperazine
179756-91-3
US $1.10 / g
99.00%
Dideu Industries Group Limited

1-(4-Trifluoromethylpyrimidin-2-yl)piperazine
179756-91-3
US $0.00 / KG
98%min
Shanghai Rlavie Technology Co ltd

1-(4-Trifluoromethylpyrimidin-2-yl)piperazine
179756-91-3
US $1.00 / kg
98%
Career Henan Chemical Co

1-(4-Trifluoromethylpyrimidin-2-yl)piperazine Spectrum

1-(4-Trifluoromethylpyrimidin-2-yl)piperazine(179756-91-3)¹HNMR

179756-91-3(1-(4-Trifluoromethylpyrimidin-2-yl)piperazine)Related Search:

1-BENZHYDRYLPIPERAZINE 1,2-Dimethylhydrazine Dihydrochloride Piperazine Fluorocytosine 1-Methylpiperazine

Pirimiphos-methyl 2-[4-[4-(TRIFLUOROMETHYL)PYRIMIDIN-2-YL]PIPERAZINO]ETHAN-1-OL 2-(4-[4-(TRIFLUOROMETHYL)PYRIMIDIN-2-YL]PIPERAZIN-1-YL)ETHYLAMINE BUTTPARK 77\12-15 1-(4-Trifluoromethylpyrimidin-2-yl)piperazine

tert-Butyl 4-[4-(trifluoromethyl)pyrimidin-2-yl]piperazine-1-carboxylate ,97% BUTTPARK 40\08-32 BUTTPARK 62\18-27 BUTTPARK 31\08-77 2-CHLORO-1-(4-[4-(TRIFLUOROMETHYL)PYRIMIDIN-2-YL]PIPERAZINO)ETHAN-1-ONE

BUTTPARK 62\18-26 2-PIPERAZIN-1-YL-4-TRIFLUOROMETHYL-PYRIMIDINE-5-CARBOXYLIC ACID METHYL ESTER AKOS B022199

1of4

1-[4-(Trifluoromethyl)pyrimid-2-yl]piperazine ,97% 1-(4-Trifluoromethylpyrimidin-2-yl)piperazine 2-(Piperazin-1-yl)-4-(trifluoromethyl)pyrimidine 2-PIPERAZIN-YL-4-(TRIFLUOROMETHYL)PYRIMIDINE 1-[4-(TrifluoroMethyl)-2-pyriMidinyl]piperazine, 97% Pyrimidine, 2-(1-piperazinyl)-4-(trifluoromethyl)- 1-(4-Trifluoromethylpyrimidin-2-yl)piperazine ISO 9001：2015 REACH 2-(1-Piperazinyl)-4-(trifluoromethyl)pyrimidine 179756-91-3 179765-91-3 pharmacetical