12(S)-HPETE
- CAS No.
- 71774-10-2
- Chemical Name:
- 12(S)-HPETE
- Synonyms
- 12(S)-HPETE;12(S)HpETE,12(S) HpETE;ZIOZYRSDNLNNNJ-LQWMCKPYSA-N;12(S)-HpETE(solution in ethanol);12(S)-HpETE Lipid Maps MS Standard;12(S)-Hydroperoxy-eicosatetraenoic acid;12(S)-hydroperoxy-5(Z),8(Z),10(E),14(Z)-ETA;(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoic acid;12S-HYDROPEROXY-5Z,8Z,10E,14Z-EICOSATETRAENOIC ACID;12(S)-HYDROPEROXYEICOSA-5Z,8Z,10E,14Z-TETRAENOIC ACID
- CBNumber:
- CB4154161
- Molecular Formula:
- C20H32O4
- Molecular Weight:
- 336.47
- MDL Number:
- MFCD00063585
- MOL File:
- 71774-10-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 12(S)-HpETE ≥98% | 44570 | 25μg | $145 |
| 12(S)-HpETE ≥98% | 44570 | 50μg | $271 |
| 12(S)-HpETE ≥98% | 44570 | 100μg | $513 |
| 12(S)-HpETE ≥98% | 44570 | 250μg | $1133 |
| 12(S)-HPETE | CS-0059562 | 50??g | $626 |
| Boiling point | 518.0±50.0 °C(Predicted) |
|---|---|
| Density | 1.013±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml |
| form | Liquid. |
| pka | 4.75±0.10(Predicted) |
| FDA UNII | 54G1W9LPV0 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501 | |||||||||
| NFPA 704 |
|
12(S)-HPETE price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 44570 | 12(S)-HpETE ≥98% | 71774-10-2 | 25μg | $145 | 2026-04-30 | Buy |
| Cayman Chemical | 44570 | 12(S)-HpETE ≥98% | 71774-10-2 | 50μg | $271 | 2026-04-30 | Buy |
| Cayman Chemical | 44570 | 12(S)-HpETE ≥98% | 71774-10-2 | 100μg | $513 | 2026-04-30 | Buy |
| Cayman Chemical | 44570 | 12(S)-HpETE ≥98% | 71774-10-2 | 250μg | $1133 | 2026-04-30 | Buy |
| ChemScene | CS-0059562 | 12(S)-HPETE | 71774-10-2 | 50??g | $626 | 2026-06-04 | Buy |
12(S)-HPETE Chemical Properties,Uses,Production
Description
12(S)-
Uses
12(S)-HPETE is a fatty acid and an activator of human blood leukocyte 5-LO.
Definition
ChEBI: 12(S)-HPETE is the (S)-enantiomer of 12-HPETE. It has a role as a mouse metabolite. It is functionally related to an icosa-5,8,10,14-tetraenoic acid. It is a conjugate acid of a 12(S)-HPETE(1-). It is an enantiomer of a 12(R)-HPETE.
References
[1] J MACLOUF P B B F de Laclos. Stimulation of leukotriene biosynthesis in human blood leukocytes by platelet-derived 12-hydroperoxy-icosatetraenoic acid.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1982, 79 19: 6042-6046. DOI: 10.1073/pnas.79.19.6042
[2] KOJI KISHIMOTO . Suicide inactivation of porcine leukocyte 12-lipoxygenase associated with its incorporation of 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid derivative[J]. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1996, 1300 1: Pages 56-62. DOI: 10.1016/0005-2760(95)00241-3
[3] C. PACE-ASCIAK B S E Granstrm. Arachidonic acid epoxides. Isolation and structure of two hydroxy epoxide intermediates in the formation of 8,11,12- and 10,11,12-trihydroxyeicosatrienoic acids.[J]. The Journal of Biological Chemistry, 1983, 48 1: 6835-6840. DOI: 10.1016/s0021-9258(18)32298-1
[4] MAKOTO NISHIYAMA . Endothelium is required for 12-hydroperoxyeicosatetraenoic acid-induced vasoconstriction[J]. European journal of pharmacology, 1998, 341 1: Pages 57-63. DOI: 10.1016/s0014-2999(97)01353-8
[5] G N RAO. Role of hydroperoxyeicosatetraenoic acids in oxidative stress-induced activating protein 1 (AP-1) activity.[J]. The Journal of Biological Chemistry, 1996, 271 44: 27760-27764. DOI: 10.1074/jbc.271.44.27760
[6] D. PIOMELLI. Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells[J]. Nature, 1987, 328 6125: 38-43. DOI: 10.1038/328038a0
[7] D PIOMELLI. Inhibition of Ca2+/calmodulin-dependent protein kinase II by arachidonic acid and its metabolites.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1989, 86 21: 8550-8554. DOI: 10.1073/pnas.86.21.8550
12(S)-HPETE Preparation Products And Raw materials
Raw materials
Preparation Products
12(S)-HPETE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 15921930842 15921930842 | yh-wang@univ-bio.com | China | 25030 | 58 |
| amyjet | 4006800868;027-59626688 18771149750 | sales@amyjet.com | China | 2909 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| SHANGHAI ZZBIO CO., LTD. | 18019219489 18901678489 | tech@zzbioco.com | China | 12062 | 58 |
View Lastest Price from 12(S)-HPETE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-17 | 12(S)-HpETE
71774-10-2
|
$475.00 | 10g | TargetMol Chemicals Inc. |
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- 12(S)-HpETE
71774-10-2
- $475.00
- TargetMol Chemicals Inc.
