Ste-MPKKKPTPIQLNP-NH2
- CAS No.
- 566872-15-9
- Chemical Name:
- Ste-MPKKKPTPIQLNP-NH2
- Synonyms
- STE-MEK1(13);Ste-MPKKKPTPIQLNP-NH2;STEARYL-MEK-1 DERIVED PEPTIDE INHIBITOR 1, AMIDE;ERK ACTIVATION INHIBITOR PEPTIDE I, CELL-PERMEABLE;STE-MET-PRO-LYS-LYS-LYS-PRO-THR-PRO-ILE-GLN-LEU-ASN-PRO-NH2;L-Prolinamide, N-(1-oxooctadecyl)-L-methionyl-L-prolyl-L-lysyl-L-lysyl-L-lysyl-L-prolyl-L-threonyl-L-prolyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-asparaginyl-
- CBNumber:
- CB4159696
- Molecular Formula:
- C86H153N19O17S
- Molecular Weight:
- 1757.32
- MDL Number:
- MFCD04974162
- MOL File:
- Mol file
- TDS File:
- TDS
| Boiling point | 1814.130±65.00 °C(Press: 760.00 Torr)(predicted) |
|---|---|
| Density | 1.196±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| storage temp. | -20°C |
| solubility | water: 1 mg/mL || DMSO: 5 mg/mL |
| form | lyophilized solid |
| pka | 13.329±0.46(predicted) |
| color | white |
| Water Solubility |
water: 1mg/mL DMSO: 5mg/mL |
| Sequence | {Ste}-Met-Pro-Lys-Lys-Lys-Pro-Thr-Pro-Ile-Gln-Leu-Asn-Pro-NH2 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
Ste-MPKKKPTPIQLNP-NH2 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 328000 | ERK Activation Inhibitor Peptide I, Cell-Permeable The ERK Activation Inhibitor Peptide I, Cell-Permeable controls the biological activity of ERK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation application | 1 mg | $229 | 2026-04-30 | Buy | |
| American Custom Chemicals Corporation | PEP0003409 | STEARYL - MEK - 1 DERIVED PEPTIDE INHIBITOR 1, AMIDE 95.00% | 1MG | $685.21 | 2021-12-16 | Buy |
Ste-MPKKKPTPIQLNP-NH2 Chemical Properties, Uses, Production
Uses
STE-MEK1(13) (Ste-MPKKKPTPIQLNP-NH ) is a cell permeable ERK1/2 inhibitor (IC50: 13-30 μM). STE-MEK1(13) inhibits ERK1/2 phosphorylation[1][2].
Biological Activity
Cell permeable: yes', 'Primary Target
MEK', 'Product does not compete with ATP.', 'Reversible: yes
References
[1] Li G, et al. A novel cellular survival factor--the B2 subunit of vacuolar H+-ATPase inhibits apoptosis. Cell Death Differ. 2006 Dec;13(12):2109-17. DOI:10.1038/sj.cdd.4401970
[2] Whiteman M, et al. Peroxynitrite-modified collagen-II induces p38/ERK and NF-kappaB-dependent synthesis of prostaglandin E2 and nitric oxide in chondrogenically differentiated mesenchymal progenitor cells. Osteoarthritis Cartilage. 2006 May;14(5):460-70. DOI:10.1016/j.joca.2005.11.002
Ste-MPKKKPTPIQLNP-NH2 Preparation Products And Raw materials
Raw materials
Preparation Products
Ste-MPKKKPTPIQLNP-NH2 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Nanjing Peptide Biotech Ltd. | 025-58361106-805 15951641583 | zhao.xu@njpeptide.com | China | 9976 | 55 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19087 | 58 |
| Nanchang Tianzhen Biotechnology Co., Ltd | 13758194781 13173652190 | 522013271@qq.com | China | 2447 | 58 |
| Hangzhou Go Top Peptide Biotech | 0571-88211921 17357109671 | sales3@gotopbio.com | China | 2988 | 58 |
| Hangzhou Sinoda Pharmaceutical Technology Co. LTD | 0571-87213919 17306812703 | 3007955328@qq.com | China | 7446 | 58 |
| Shanghai HongTide Biotechnology Co.,Ltd. | 15318089928 | alex@hanhonggroup.com | China | 4604 | 58 |
| Fuan Bio | 15002819872 | 2845971812@qq.com | China | 2103 | 58 |
