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13,14-Dihydro-15-keto prostaglandin E1

CAS No.
5094-14-4
Chemical Name:
13,14-Dihydro-15-keto prostaglandin E1
Synonyms
U 21002;13,14-dihydro-15-keto PGE1;CDUVSQMTLOYKTR-ZHALLVOQSA-N;13,14-Dihydro-15-keto prostaglandin E1;9,15-dioxo-11α-hydroxy-prostan-1-oic acid;9,15-DIOXO-11ALPHA-HYDROXY-PROSTAN-1-OIC ACID;Prostan-1-oic acid, 11-hydroxy-9,15-dioxo-, (11α)-;15-Keto Prostaglandin E0 DISCONTINUED, OFFER K202056
CBNumber:
CB4190392
Molecular Formula:
C20H34O5
Molecular Weight:
354.49
MDL Number:
MFCD00135210
MOL File:
5094-14-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:52:32

13,14-Dihydro-15-keto prostaglandin E1 Properties

Boiling point 537.2±35.0 °C(Predicted)
Density 1.072±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly), THF (Slightly)
pka 4.77±0.10(Predicted)
form Oil
color Dark Yellow
FDA UNII M3I99MYM0V

13,14-Dihydro-15-keto prostaglandin E1 price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 13650 13,14-dihydro-15-keto Prostaglandin E1 ≥98% 5094-14-4 1mg $71 2026-04-30 Buy
Cayman Chemical 13650 13,14-dihydro-15-keto Prostaglandin E1 ≥98% 5094-14-4 5mg $308 2026-04-30 Buy
Cayman Chemical 13650 13,14-dihydro-15-keto Prostaglandin E1 ≥98% 5094-14-4 10mg $547 2026-04-30 Buy
ChemScene CS-0140520 13,14-Dihydro-15-keto-PGE1 5094-14-4 1mg $153 2026-06-04 Buy
ChemScene CS-0140520 13,14-Dihydro-15-keto-PGE1 5094-14-4 5mg $667 2026-06-04 Buy
Product number Packaging Price Buy
13650 1mg $71 Buy
13650 5mg $308 Buy
13650 10mg $547 Buy
CS-0140520 1mg $153 Buy
CS-0140520 5mg $667 Buy

13,14-Dihydro-15-keto prostaglandin E1 Chemical Properties, Uses, Production

Description

13,14-dihydro-15-keto Prostaglandin E1 (PGE1) is a metabolite of PGE1 with much reduced biological activity. Steady state plasma concentrations are about 10 pg/ml. 13,14-dihydro-15-keto PGE1 is a weak inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 54 and 200 μM, respectively, compared to PGE1 which has an IC50 of 40 nM.

Uses

15-Keto Prostaglandin E0 is a metabolite of Prostaglandin E1 (P838600) and has been shown to induce arterial thromboresistance in experimental animals and in man, but with several magnitudes higher concentrations than Prostaglandin E1. 15-Keto Prostaglandin E0 is also used as the active ingredient in compositions used for the treatment of external secretion disorders.

Definition

ChEBI: 13,14-dihydro-15-oxoprostaglandin E1 is a prostaglandin E obtained by formal oxidation of the 15-hydroxy group and hydrogenation of the 13,14-double bond of prostaglandin E1. It has a role as a human xenobiotic metabolite. It is functionally related to a prostaglandin E1. It is a conjugate acid of a 13,14-dihydro-15-oxoprostaglandin E1(1-).

References

[1] R. KATZENSCHLAGER . Synergism between PGE1-metabolites (13,14-dihydro-prostaglandin E1, 15-keto prostaglandin E1, 15-keto-13,14-dihydro-prostaglandin E1) and nitric oxide (NO) on platelet aggregation[J]. Prostaglandins, leukotrienes, and essential fatty acids, 1992, 45 3: Pages 207-210. DOI: 10.1016/0952-3278(92)90114-x

13,14-Dihydro-15-keto prostaglandin E1 Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 19)
Supplier Tel Email Country ProdList Advantage
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD 0755-83725350 13380397412 3001280422@qq.com China 10000 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44871 58
Hubei Aiputi Bioengineering Co., Ltd. 17762444226 d17762444226@163.com China 2400 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
9,15-DIOXO-11ALPHA-HYDROXY-PROSTAN-1-OIC ACID CDUVSQMTLOYKTR-ZHALLVOQSA-N 13,14-dihydro-15-keto PGE1 9,15-dioxo-11α-hydroxy-prostan-1-oic acid U 21002 Prostan-1-oic acid, 11-hydroxy-9,15-dioxo-, (11α)- 15-Keto Prostaglandin E0 DISCONTINUED, OFFER K202056 13,14-Dihydro-15-keto prostaglandin E1 5094-14-4