ChemicalBook >> CAS DataBase List >>13,14-Dihydro-prostaglandin E1 (PGE0)

13,14-Dihydro-prostaglandin E1 (PGE0)

CAS No.
19313-28-1
Chemical Name:
13,14-Dihydro-prostaglandin E1 (PGE0)
Synonyms
PGE0;13,14-dihydro PGE1;Prostaglandin E0 >AlprostadilImpurity5;13,14-Dihydroprostaglandinee1;13,14-DIHYDROPROSTAGLANDIN E1;Prostaglandin E1 Impurity 5 (PGE0);90% (20% solution in ethyl acetate);13,14-Dihydro-prostaglandin E1 (PGE0);9-oxo-11α,15S-dihydroxy-prostan-1-oic acid
CBNumber:
CB2233138
Molecular Formula:
C20H36O5
Molecular Weight:
356.5
MDL Number:
MFCD00135208
MOL File:
19313-28-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 00:01:14

13,14-Dihydro-prostaglandin E1 (PGE0) Properties

Boiling point 541.4±35.0 °C(Predicted)
Density 1.075±0.06 g/cm3(Predicted)
storage temp. Refrigerator, under inert atmosphere
solubility Ethyl Acetate, Methanol, Tetrahydrofuran
form Colorless to pale yellow oil
pka 4.77±0.10(Predicted)
Stability Volatile
FDA UNII C1R6440YGW

SAFETY

Risk and Safety Statements

13,14-Dihydro-prostaglandin E1 (PGE0) price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 13610 13,14-dihydro Prostaglandin E1 ≥98% 19313-28-1 500μg $52 2026-04-30 Buy
Cayman Chemical 13610 13,14-dihydro Prostaglandin E1 ≥98% 19313-28-1 1mg $96 2026-04-30 Buy
Cayman Chemical 13610 13,14-dihydro Prostaglandin E1 ≥98% 19313-28-1 5mg $396 2026-04-30 Buy
Cayman Chemical 13610 13,14-dihydro Prostaglandin E1 ≥98% 19313-28-1 10mg $692 2026-04-30 Buy
TRC TRC-P838606-25MG Prostaglandin E0 >90% (20% solution in ethyl acetate) 19313-28-1 25mg $3316 2026-06-03 Buy
Product number Packaging Price Buy
13610 500μg $52 Buy
13610 1mg $96 Buy
13610 5mg $396 Buy
13610 10mg $692 Buy
TRC-P838606-25MG 25mg $3316 Buy

13,14-Dihydro-prostaglandin E1 (PGE0) Chemical Properties,Uses,Production

Description

13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound. It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM, respectively. 13,14-dihydro PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 which has an IC50 value of 40 nM. Also, 13,14-dihydro PGE1 was shown to activate adenylate cyclase in NCB-20 hybrid cells with a Kact value of 668 nM.

Uses

Prostaglandin E0 is a metabolite of Prostaglandin E1 (P838600) and can inhibit aggregation, ATP release, and thromboxane generation by human platelets. Prostaglandin E0 can also decrease the formation of cyclooxygenase (COX) metabolites by inhibiting the induction of COX-2 protein by LPS.

Definition

ChEBI: 13,14-Dihydro PGE1 is a prostanoid.

References

[1] [1] NGGRD E. The Biological Activities of Three Metabolites of Prostaglandin E1[J]. Acta Physiologica, 1966, 66 4: 509-510. DOI: 10.1111/j.1748-1716.1966.tb03231.x
[2] M. HAMBERG B S. On the Metabolism of Prostaglandins E1 and E2 in Man[J]. Journal of Biological Chemistry, 1971, 246 1: 6713-6721. DOI: 10.1016/s0021-9258(19)45905-x
[3] G. KOBZAR. Comparison of the inhibitory effect of E-prostaglandins in human and rabbit platelet-rich plasma and washed platelets[J]. Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, 1993, 106 2: Pages 489-494. DOI: 10.1016/0742-8413(93)90168-k
[4] I. JRVING. ANTIAGGREGATING POTENCY OF E-TYPE PROSTAGLANDINS IN HUMAN AND RABBIT PLATELETS[J]. Proceedings of the Estonian Academy of Sciences. Chemistry, 1991, 32 1. DOI: 10.3176/chem.1991.3.09
[5] I.A. BLAIR  J. M  C N HENSBY. PROSTACYCLIN-DEPENDENT ACTIVATION OF ADENYLATE CYCLASE IN A NEURONAL SOMATIC CELL HYBRID: PROSTANOID STRUCTURE-ACTIVITY RELATIONSHIPS[J]. British Journal of Pharmacology, 1980, 69 3: 519-525. DOI: 10.1111/j.1476-5381.1980.tb07043.x

13,14-Dihydro-prostaglandin E1 (PGE0) Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 47)Suppliers
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Shanghai Synchem Pharma Co., ltd 21-619849051-1 18521059765 synchempharma@aliyun.com China 4988 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Jinan blalong chemical co. LTD 2710913286@qq.com 1513643261@qq.com China 14227 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58

View Lastest Price from 13,14-Dihydro-prostaglandin E1 (PGE0) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
13,14-dihydro Prostaglandin E1 pictures 2026-05-11 13,14-dihydro Prostaglandin E1
19313-28-1
$316.00-2270.00 10g TargetMol Chemicals Inc.
9-OXO-11ALPHA,15S-DIHYDROXY-PROSTAN-1-OIC ACID 13,14-DIHYDROPROSTAGLANDIN E1 13,14-Dihydroprostaglandinee1 13,14-dihydro PGE1 7-[(1R,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoctyl]-5-oxocyclopentyl]heptanoic acid (11R)-11α,15α-Dihydroxy-9-oxoprostan-1-oic acid Prostan-1-oic acid,11,15-dihydroxy-9-oxo-, (11a,15S)- 13,14-Dihydro-prostaglandin E1 (PGE0) 9-oxo-11α,15S-dihydroxy-prostan-1-oic acid Prostaglandin E0 > 90% (20% solution in ethyl acetate) Prostaglandin E1 Impurity 5 (PGE0) Prostan-1-oic acid, 11,15-dihydroxy-9-oxo-, (11α,15S)- Prostaglandin E0 >90% (20% solution in ethyl acetate) AlprostadilImpurity5 Alprostadil (Prostaglandin E1) Impurity 5 (PGE0) Alprostadil (prostaglandin E1) Impurity 12 (PGE0) 13,14-Dihydroprostaglandin E1, Prostaglandin E1 (PGE1) metabolite PGE0 19313-28-1