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2-Di-t-butylphosphino-2'-(N,N-dimethylamino)biphenyl

2-Di-t-butylphosphino-2'-(N,N-dimethylamino)biphenyl structure

CAS No.: 224311-49-3

Chemical Name:: 2-Di-t-butylphosphino-2'-(N,N-dimethylamino)biphenyl

Synonyms: tBuDavePhos;t-Butyl DavePhos;2'-(Di-tert-butylphosphino)-N,N-dimethyl-[1,1'-biphenyl]-2-amine;2'-(Di-tert-butylphosphino)-N,N-dimethyl-[1,1'-biphenyl]-2-amine;98% tBuDav;98% tBuDavePhos;t-BuDavePhos 97%;t-BuDavePhos;2-(Di-tert-butylphosphino)-2'-;2-(Di-tert-butylphosphino)-2'-(N,N-dimethylamino)b

CBNumber:: CB4192659

Molecular Formula:: C22H32NP

Molecular Weight:: 341.47

MDL Number:: MFCD03426986

MOL File:: 224311-49-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 02:06:33

Product description	Number	Pack Size	Price
t-BuDavePhos 97%	695874	1g	$205
t-BuDavePhos 97%	695874	5g	$361.5
2-Di-t-butylphosphino-2'-(N,N-dimethylamino))-1,1'-biphenyl, 98% tBuDavePhos 98%	15-1048	500mg	$57
2-Di-t-butylphosphino-2'-(N,N-dimethylamino))-1,1'-biphenyl, 98% tBuDavePhos 98%	15-1048	2g	$160
2-Di-t-butylphosphino-2'-(N,N-dimethylamino))-1,1'-biphenyl, 98% tBuDavePhos 98%	15-1048	10g	$632
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2-Di-t-butylphosphino-2'-(N,N-dimethylamino)biphenyl Properties

Melting point	115-117 °C
Boiling point	451.6±38.0 °C(Predicted)
storage temp.	Inert atmosphere,Room Temperature
pka	5.07±0.18(Predicted)
form	crystal
color	white
Sensitive	Air Sensitive
InChI	InChI=1S/C22H32NP/c1-21(2,3)24(22(4,5)6)20-16-12-10-14-18(20)17-13-9-11-15-19(17)23(7)8/h9-16H,1-8H3
InChIKey	PHLPNEHPCYZBNZ-UHFFFAOYSA-N
SMILES	C1(C2=CC=CC=C2P(C(C)(C)C)C(C)(C)C)=CC=CC=C1N(C)C
UNSPSC Code	12352116
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335-H413

Precautionary statements

P273-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

37/39-26

WGK Germany

TSCA

HS Code

29319090

Storage Class

11 - Combustible Solids

Hazard Classifications

Aquatic Chronic 4
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	0
2		1

2-Di-t-butylphosphino-2'-(N,N-dimethylamino)biphenyl price More Price(58)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	695874	t-BuDavePhos 97%	224311-49-3	1g	$205	2026-04-30	Buy
Sigma-Aldrich	695874	t-BuDavePhos 97%	224311-49-3	5g	$361.5	2026-04-30	Buy
Strem Chemicals	15-1048	2-Di-t-butylphosphino-2'-(N,N-dimethylamino))-1,1'-biphenyl, 98% tBuDavePhos 98%	224311-49-3	500mg	$57	2026-04-30	Buy
Strem Chemicals	15-1048	2-Di-t-butylphosphino-2'-(N,N-dimethylamino))-1,1'-biphenyl, 98% tBuDavePhos 98%	224311-49-3	2g	$160	2026-04-30	Buy
Strem Chemicals	15-1048	2-Di-t-butylphosphino-2'-(N,N-dimethylamino))-1,1'-biphenyl, 98% tBuDavePhos 98%	224311-49-3	10g	$632	2026-04-30	Buy

Product number	Packaging	Price	Buy
695874	1g	$205	Buy
695874	5g	$361.5	Buy
15-1048	500mg	$57	Buy
15-1048	2g	$160	Buy
15-1048	10g	$632	Buy

2-Di-t-butylphosphino-2'-(N,N-dimethylamino)biphenyl Chemical Properties,Uses,Production

Reaction

Useful ligand for Pd-catalyzed carbon-oxygen bond forming reactions.
Ligand used selective Pd-catalyzed arylation of ammonia. Application to the synthesis of dibenzodiazepines.
Ligand used for selective Pd-catalyzed silylation of aryl chlorides.
Ligand used for Pd(0)-catalyzed direct dehydrative coupling of terminal alkynes with allylic alcohols to access 1,4-enynes.

Chemical Properties

White crystals or crystalline powder

Uses

suzuki reaction

reaction suitability

reagent type: ligand
reaction type: Arylations
reagent type: ligand
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reagent type: ligand
reaction type: C-X Bond Formation

Synthesis

The target compound 2-di-tert-butylphosphine-2-(N,N-dimethylamino)biphenyl was prepared by the Suzuki reaction using 2-bromochlorobenzene as starting material, followed by the reaction with di-tert-butylphosphonium chloride.

2-Di-t-butylphosphino-2'-(N,N-dimethylamino)biphenyl Preparation Products And Raw materials

Raw materials

Preparation Products

Methanesulfonato2-Di-t-butylphosphino-2'-(N,N-dimethylamino)biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II)

2-Di-t-butylphosphino-2'-(N,N-dimethylamino)biphenyl Suppliers

Global( 233)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
XINXIANG RUNYU MATERIAL CO., LTD.	+86-13592593621; +8613592593621	sales@runvmat.com	China	458	58
Henan Research New Materials Co., Ltd.	+86-18903931628 +86-18903931531	sales036@researchvip.com	China	302	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971	deasea125996@gmail.com	China	2472	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16512	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13901	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2972	58

Supplier	Advantage
XINXIANG RUNYU MATERIAL CO., LTD.	58
Henan Research New Materials Co., Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Nanjing Dolon Biotechnology Co.,Ltd.	58

View Lastest Price from 2-Di-t-butylphosphino-2'-(N,N-dimethylamino)biphenyl manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-06-04	2'-(Di-tert-butylphosphino)-N,N-dimethylbiphenyl-2-amine 224311-49-3		1Kg	98％	1000kg	Henan Research New Materials Co., Ltd.
2026-06-03	2-Di-tert-butylphosphino-2'-(N,N-dimethylamino)biphenyl 224311-49-3		50G	98%min	30KG/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-04-17	2-di-t-butylphosphino-2'-(n,n-dimethylamino)biphenyl 224311-49-3	$2.00-5.00	1kg	99%	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

2'-(Di-tert-butylphosphino)-N,N-dimethylbiphenyl-2-amine
224311-49-3
$0.00
98％
Henan Research New Materials Co., Ltd.

2-Di-tert-butylphosphino-2'-(N,N-dimethylamino)biphenyl
224311-49-3
$0.00
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

2-di-t-butylphosphino-2'-(n,n-dimethylamino)biphenyl
224311-49-3
$2.00-5.00
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

2-Di-t-butylphosphino-2'-(N,N-dimethylamino)biphenyl Spectrum

2-DI-T-BUTYLPHOSPHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL(224311-49-3)¹HNMR 2-DI-T-BUTYLPHOSPHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL(224311-49-3)³¹PNMR

224311-49-3(2-Di-t-butylphosphino-2'-(N,N-dimethylamino)biphenyl)Related Search:

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2-DICYCLOHEXYLPHOSPHINO-2',4',6'-TRIISO& 2-Diphenylphosphino-2'-(N,N-dimethylamino)biphenyl 2-DIPHENYLPHOSPHINO-6-METHYLPYRIDINE T-BUTYLPHOSPHINE Di-tert-butylphosphine

2-(Di-tert-butylphosphino)biphenyl DI-TERT-BUTYLPHENYLPHOSPHINE 2-DI-T-BUTYLPHOSPHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL

1of3

2'-[Bis(1,1-dimethylethyl)phosphino]-N,N-dimethyl-[1,1'-biphenyl]-2-amine 2-Di-tert-butylphosphino-2'-(N,N-dimethylamino)biphenyl,98% 2-[2-(di-tert-butylphosphanyl)phenyl]-N,N-diMethylaniline 98% tBuDavePhos 2-(Di-tert-butylphosphiNA)-2'-(N,N-diMethylaMiNA)biphenyl 2-(Di-tert-butylphosphino)-2'- 2-Di-t-butylphosphino-2'-(N,N-diMethylaMino)biphenyl,98% tBuDavePhos t-BuDavePhos 97% 2-Di-t-butylphosphino-2'-(N,N-dimethylamino))-1,1'-biphenyl, 98% 2-Di-t-butylphosphino-2'-(N,N-dimethylamino)biphenyl, (tBuDavePhos) 2′-(Di-tert-butylphosphino)-N,N-dimethylbiphenyl-2-amine t-Butyl DavePhos 2-DI-T-BUTYLPHOSPHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL [2'-(DI-TERT-BUTYL-PHOSPHANYL)-BIPHENYL-2-YL]-DIMETHYL-AMINE 2-DI-TERT-BUTYLPHOSPHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL 2-DI-TERT-BUTYLPHOSHINO-2'-(N,N-DIMETHYLAMINO)BIPHENYL 2-Di-t-butylphosphino-2'-(N,N-dimethylamino)biphenyl,98% 2-Di-t-butylphosphino-2'-(N,N-dimethylamino))-1,1'-biphenyl, 98% tBuDavePhos 2-(Di-tert-butylphosphino)-2'-(N,N-dimethylamino)b 98% tBuDav [1,1''-BIPHENYL]-2-AMINE, 2''-[BIS(1,1-DIMETHYLETHYL)PHOSPHINO]-N,N-DIMETHYL- 2-DI-T-BUTYLPHOSHINO-2''-(N,N-DIMETHYLAMINO)BIPHENYL 2-(2-ditert-butylphosphinophenyl)-N,N-dimethylaniline 2-Di-t-butylphosphino-2'-(N,N-dimethylamino))-1,1'-biphenyl,98% 2-Di-t-butylphosphino-2'-(N,N-dimethylamino))-1,1'-biphenyl 2-(Di-tert-butylphosphino)-2'-(N,N-dimethylamino)biphenyl 2'-(Di-tert-butylphosphino)-N,N-dimethylbiphenyl-2-amine 2'-[Bis(1,1-dimethylethyl)phosphino]-N,N-dimethyl[1,1'-biphenyl]-2-amine 2-Di-t-butylphosphino-2'-(N,N-diMethylaMino)biphenyl (tBuDavePhos) t-BuDavePhos 2-Di-tert-butylphosphino-2'-(N,N-dimethylamino)-1,1'-biphenyl,tBuDavePhos 2'-(Di-tert-butylphosphino)-N,N-dimethyl-[1,1'-biphenyl]-2-amine 2'-(Di-tert-butylphosphino)-N,N-dimethyl-[1,1'-biphenyl]-2-amine tBuDavePhos 224311-49-3 224311-43-3 C22H32NP CH32NC6H4C6H4PC4H92 Phosphines Achiral Phosphine Aryl Phosphine Buchwald Ligands Series Buchwald Ligands&Precatalysts