7-Amino-4-methyl-3-coumarinylacetic acid
- CAS No.
- 106562-32-7
- Chemical Name:
- 7-Amino-4-methyl-3-coumarinylacetic acid
- Synonyms
- AMCA-H;AMCA blue;AMCA acid;AMCA (coumarin);AMCA Free Acid (Blue);2H-1-Benzopyran-3-acetic acid;AMCA acid *CAS#: 106562-32-7*;AMINO-METHYL-COUMARINACETICACID;7-Amino-4-methylcoumarin-3-aceticAcid>7-Amino-4-methyl-3-coumarinylacetic acid
- CBNumber:
- CB4196576
- Molecular Formula:
- C12H11NO4
- Molecular Weight:
- 233.22
- MDL Number:
- MFCD00081051
- MOL File:
- 106562-32-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 512.2±50.0 °C(Predicted) |
|---|---|
| Density | 1.391±0.06 g/cm3 (20 ºC 760 Torr) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMF: soluble |
| pka | 3.80±0.10(Predicted) |
| form | powder to crystal |
| color | Light yellow to Brown |
| Appearance | Solid |
| λmax | 344nm(Buffer)(lit.) |
| BRN | 7927205 |
| InChI | InChI=1S/C12H11NO4/c1-6-8-3-2-7(13)4-10(8)17-12(16)9(6)5-11(14)15/h2-4H,5,13H2,1H3,(H,14,15) |
| InChIKey | QEQDLKUMPUDNPG-UHFFFAOYSA-N |
| SMILES | C1(=O)OC2=CC(N)=CC=C2C(C)=C1CC(O)=O |
| UNSPSC Code | 12352106 |
| NACRES | NA.32 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29322090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
7-Amino-4-methyl-3-coumarinylacetic acid price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 08445 | 7-Amino-4-methyl-3-coumarinylacetic acid BioReagent, suitable for fluorescence, ~90% (HPLC) | 106562-32-7 | 100mg | $118 | 2026-04-30 | Buy |
| Sigma-Aldrich | 08445 | 7-Amino-4-methyl-3-coumarinylacetic acid BioReagent, suitable for fluorescence, ~90% (HPLC) | 106562-32-7 | 500mg | $214 | 2026-04-30 | Buy |
| TCI Chemical | A2820 | 7-Amino-4-methylcoumarin-3-acetic Acid >95.0%(T) | 106562-32-7 | 50mg | $49 | 2026-04-30 | Buy |
| TCI Chemical | A2820 | 7-Amino-4-methylcoumarin-3-acetic Acid >95.0%(T) | 106562-32-7 | 250mg | $157 | 2026-04-30 | Buy |
| Cayman Chemical | 29184 | AMCA ≥90% | 106562-32-7 | 25mg | $36 | 2026-04-30 | Buy |
7-Amino-4-methyl-3-coumarinylacetic acid Chemical Properties, Uses, Production
Description
AMCA is fluorescent protein labeling agent. It contains an N-hydroxysuccinimide ester that reacts with lysine residues to form photostable amide links. Upon activation with UV light, AMCA displays emission maxima of 400-460 nm. It has commonly been used in multiplex immunophenotyping applications.
Uses
7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID is a blue fluorescent dye. Its desirable properties include a relatively large Stoke's shift and resistance to photobleaching. 7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID is used as contrasting probes for double and triple labeling in im
Uses
Non-Activated, Amine-Reactive, fluorescent probe
Chemical Reactivity
Primary amines (needs activation)
References
[1] H. KHALFAN. Aminomethyl coumarin acetic acid: A new fluorescent labelling agent for proteins[J]. Journal of Molecular Histology, 1986, 18 9: 497-499. DOI: 10.1007/bf01675617
[2] G L FERRI. Quadruple immunofluorescence: a direct visualization method.[J]. Journal of Histochemistry & Cytochemistry, 1997, 45 2: 155-158. DOI: 10.1177/002215549704500201
[3] P. M. NEDERLOF. Three-color fluorescence in situ hybridization for the simultaneous detection of multiple nucleic acid sequences[J]. Cytometry Part B: Clinical Cytometry, 1989, 10 1: 20-27. DOI: 10.1002/cyto.990100105
[4] ANDRé GOTHOT Jean M P Jean Claude Grosdent. A strategy for multiple immunophenotyping by image cytometry: Model studies using latex microbeads labeled with seven streptavidin-bound fluorochromes[J]. Cytometry Part A, 1996, 24 3: 214-225. DOI: 10.1002/(sici)1097-0320(19960701)24:3<214::aid-cyto4>3.0.co;2-h
Abs/Em Maxima
345/450 nm
Extinction Coefficient
19,000 cm-1M-1
Spectrally Similar Dyes
Alexa Fluor® 350, AMCA, DyLight® 350
7-Amino-4-methyl-3-coumarinylacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Santai Labs, Inc. | 519-85601385 | marketing@santailabs.com | China | 891 | 62 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
| Beijing Yisiyan Technology Research Center | 010-56645598 13366904824; | bjkaida@163.com | China | 1596 | 59 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
View Latest Price from 7-Amino-4-methyl-3-coumarinylacetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | 7-Amino-4-methylcoumarin-3-acetic acid
106562-32-7
|
$29.00-32.00 | 98.38% | 10g | TargetMol Chemicals Inc. | ||
 |
2020-01-10 | 7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID
106562-32-7
|
$1.00 | 1KG | 98% HPLC | 10 tons/month | Career Henan Chemical Co |
-
- 7-Amino-4-methylcoumarin-3-acetic acid
106562-32-7
- $29.00-32.00
- 98.38%
- TargetMol Chemicals Inc.
-
- 7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID
106562-32-7
- $1.00
- 98% HPLC
- Career Henan Chemical Co
