Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1-Benzyl-4-(4-nitrophenyl)piperazine

1-Benzyl-4-(4-nitrophenyl)piperazine

1-Benzyl-4-(4-nitrophenyl)piperazine Structure
1-Benzyl-4-(4-nitrophenyl)piperazine structure
CAS No.
16155-08-1
Chemical Name:
1-Benzyl-4-(4-nitrophenyl)piperazine
Synonyms
1-Benzyl-4-(4-nitrophenyl)piperazine;1-BENZYL-4-(4-NITROPHENYL)PIPERAZINE, 95+%;1-(4-nitrophenyl)-4-(phenylmethyl)piperazine;Piperazine, 1-(4-nitrophenyl)-4-(phenylmethyl)-
CBNumber:
CB4205405
Molecular Formula:
C17H19N3O2
Molecular Weight:
297.35
MDL Number:
MFCD00215725
MOL File:
16155-08-1.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:33
Request For Quotation

1-Benzyl-4-(4-nitrophenyl)piperazine Properties

Melting point 112 °C
Boiling point 461.7±45.0 °C(Predicted)
Density 1.224±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 7.20±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338

1-Benzyl-4-(4-nitrophenyl)piperazine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 071898 1-Benzyl-4-(4-nitrophenyl)piperazine 16155-08-1 1.00g $162 2026-05-18 Buy
Matrix Scientific 071898 1-Benzyl-4-(4-nitrophenyl)piperazine 16155-08-1 5.00g $439 2026-05-18 Buy
Matrix Scientific 071898 1-Benzyl-4-(4-nitrophenyl)piperazine 16155-08-1 10.00g $626 2026-05-18 Buy
aablocks AA001VLU 1-Benzyl-4-(4-Nitrophenyl)Piperazine 98% 16155-08-1 1g $52 2026-05-28 Buy
aablocks AA001VLU 1-Benzyl-4-(4-Nitrophenyl)Piperazine 98% 16155-08-1 5g $135 2026-05-28 Buy
Product number Packaging Price Buy
071898 1.00g $162 Buy
071898 5.00g $439 Buy
071898 10.00g $626 Buy
AA001VLU 1g $52 Buy
AA001VLU 5g $135 Buy

1-Benzyl-4-(4-nitrophenyl)piperazine Chemical Properties, Uses, Production

Synthesis

1-Benzylpiperazine

2759-28-6

4-Fluoronitrobenzene

350-46-9

1-BENZYL-4-(4-NITROPHENYL)PIPERAZINE

16155-08-1

Example 1 Preparation of 1-benzyl-4-(4-nitrophenyl)piperazine: 1-benzylpiperazine (8.81 g, 50.0 mmol), 4-fluoronitrobenzene (5.31 mL, 50.0 mmol), and potassium carbonate (6.90 g, 50.0 mmol) were dissolved in ethanol, heated to reflux temperature, and stirred for 18 hours, under nitrogen protection. After completion of the reaction, it was cooled to room temperature, the reaction mixture was diluted with water and extracted with dichloromethane. The organic phases were combined, dried with anhydrous magnesium sulfate and concentrated under reduced pressure to give a solid residue. The solid was ground with a 20:80 solvent mixture of ethyl acetate-hexane and filtered. The filter cake was air dried to give the title compound 1-benzyl-4-(4-nitrophenyl)piperazine as orange crystals in a yield of 8.45 g (57% yield) with a melting point of 218-219°C. The structure of the product was confirmed by nuclear magnetic resonance (NMR) and mass spectrometry (MS) analysis.

References

[1] British Journal of Pharmacology, 2018, vol. 175, # 12, p. 2399 - 2413
[2] European Journal of Organic Chemistry, 2001, # 16, p. 3105 - 3118
[3] Journal of Medicinal Chemistry, 2005, vol. 48, # 26, p. 8261 - 8269
[4] Patent: WO2005/7625, 2005, A2. Location in patent: Page 61
[5] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 5, p. 1092 - 1099

1-Benzyl-4-(4-nitrophenyl)piperazine Preparation Products And Raw materials

Raw materials

1-Benzylpiperazine 1-(4-Nitrophenyl)piperazine Benzyl bromide 4-Chloronitrobenzene 4-Fluoronitrobenzene
Potassium carbonate Ethanol

1of2

Preparation Products

1-Benzyl-4-(4-nitrophenyl)piperazine Suppliers

Global Suppliers ( 42)
Supplier Tel Email Country ProdList Advantage
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
Amatek Scientific Co. Ltd. 0512-56316828 4008675858 sales@amateksci.com China 9849 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Taian Jiaye Biotechnology Co.Ltd 15318151873;13127280945 285424065@qq.com China 9961 55
Amatek Scientific Co. Ltd. 0512-56316828 400-867-5858;400-867-5858 info@amateksci.com China 28760 58
Aikon International Limited 025-58859352 19370895928 sales01@aikonchem.com China 15078 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 021-4009004166/18616739031 18616739031 3007523370@qq.com China 40000 58
Career Henan Chemica Co +86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30203 58
Supplier Advantage
Pure Chemistry Scientific Inc. 62
9ding chemical ( Shanghai) Limited 56
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
Amatek Scientific Co. Ltd. 55
Amadis Chemical Company Limited 58
Taian Jiaye Biotechnology Co.Ltd 55
Amatek Scientific Co. Ltd. 58
Aikon International Limited 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 58
Career Henan Chemica Co 58

16155-08-1 (1-Benzyl-4-(4-nitrophenyl)piperazine) Related Search:

Piperazine Methyl 1-[3-(4-([4-(4-nitrophenyl)piperazino]methyl)phenoxy)propyl]-4-piperidinecarboxylate 1-[Bis(4-fluorophenyl)methyl]-4-(4-nitrophenyl)piperazine 2-((2-[4-(1,3-Benzodioxol-5-ylmethyl)piperazino]-5-nitrophenyl)methylene)-3-quinuclidinone 5-(4-Benzylpiperazino)-2-nitroaniline
1-[4-(3-Fluoropropoxy)benzyl]-4-(4-nitrophenyl)piperazine 1-Benzyl-4-(4-nitrophenyl)piperazine Methyl 2-(4-benzylpiperazino)-5-nitrobenzenecarboxylate 4-Benzyl-N-(2-nitrophenyl)piperazine-1-propanamide TIMTEC-BB SBB009854
CPNQ

1of3

1-BENZYL-4-(4-NITROPHENYL)PIPERAZINE, 95+% 1-(4-nitrophenyl)-4-(phenylmethyl)piperazine Piperazine, 1-(4-nitrophenyl)-4-(phenylmethyl)- 1-Benzyl-4-(4-nitrophenyl)piperazine 16155-08-1