ChemicalBook >> CAS DataBase List >>10,11-Dihydro-alpha-methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid

10,11-Dihydro-alpha-methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid

10,11-Dihydro-alpha-methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid structure

CAS No.: 74711-43-6

Chemical Name:: 10,11-Dihydro-alpha-methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid

Synonyms: Soleton;ZALTOPROFEN;Salafapinon;Zatobuprofen;Einecs 277-973-5;Zaltoprofen, >=99%;Zaltoprofen (CN100);Zaltoprofen (unspecified);Zaltoprofen, 10 mM in DMSO;CN100;SOLETON;CN-100;CN 100

CBNumber:: CB42131285

Molecular Formula:: C17H14O3S

Molecular Weight:: 298.36

MDL Number:: MFCD00864323

MOL File:: 74711-43-6.mol

MSDS File:: SDS

Last updated:2025-10-16 11:50:49

Product description	Number	Pack Size	Price
Zaltoprofen >98.0%(HPLC)(T)	Z0021	1g	$27
Zaltoprofen >98.0%(HPLC)(T)	Z0021	5g	$105
Zaltoprofen ≥98%	14662	10mg	$86
Zaltoprofen ≥98%	14662	50mg	$169
Zaltoprofen ≥98%	14662	100mg	$228
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10,11-Dihydro-alpha-methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid Properties

Melting point	129-1310C
Boiling point	500.5±50.0 °C(Predicted)
Density	1.329±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	4.21±0.10(Predicted)
color	Off-White to Pale Yellow
Merck	14,10112
InChI	InChI=1S/C17H14O3S/c1-10(17(19)20)11-6-7-15-12(8-11)9-14(18)13-4-2-3-5-16(13)21-15/h2-8,10H,9H2,1H3,(H,19,20)
InChIKey	MUXFZBHBYYYLTH-UHFFFAOYSA-N
SMILES	C(C1=CC=C2SC3=CC=CC=C3C(CC2=C1)=O)(C)C(=O)O
EWG's Food Scores	1
FDA UNII	H8635NG3PY

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P264-P270-P301+P312-P330-P501

RTECS

HQ2526700

HS Code

2934.99.4400

NFPA 704

	0
2		0

10,11-Dihydro-alpha-methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid price More Price(41)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	Z0021	Zaltoprofen >98.0%(HPLC)(T)	74711-43-6	1g	$27	2025-07-31	Buy
TCI Chemical	Z0021	Zaltoprofen >98.0%(HPLC)(T)	74711-43-6	5g	$105	2025-07-31	Buy
Cayman Chemical	14662	Zaltoprofen ≥98%	74711-43-6	10mg	$86	2024-03-01	Buy
Cayman Chemical	14662	Zaltoprofen ≥98%	74711-43-6	50mg	$169	2024-03-01	Buy
Cayman Chemical	14662	Zaltoprofen ≥98%	74711-43-6	100mg	$228	2024-03-01	Buy

Product number	Packaging	Price	Buy
Z0021	1g	$27	Buy
Z0021	5g	$105	Buy
14662	10mg	$86	Buy
14662	50mg	$169	Buy
14662	100mg	$228	Buy

10,11-Dihydro-alpha-methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid Chemical Properties,Uses,Production

Chemical Properties

Off-White to Pale Yellow Solid

Uses

Zaltoprofen is a non-steroidal anti-inflammatory drug. It inhibits bradykinin-induced pain responses without blocking bradykinin receptors.

Uses

Anti-inflammatory activity resides in (S)-enantiomer.

Definition

ChEBI: Zaltoprofen is an organic molecular entity.

in vivo

Zaltoprofen (5-20 mg/kg; a single p.o.) inhibits bradykinin-induced nociceptive responses in rats^[2].
Zaltoprofen (3-30 mg/kg; a single p.o.) inhibits the acetic acid-induced writhing response of mice in a dose-dependent manner^[2].

Animal Model:	Eight-week-old male Wistar rats were injected Bradykinin every 15 min^[2]
Dosage:	5, 10, 20 mg/kg
Administration:	A single p.o.
Result:	Inhibited bradykinin-induced nociceptive responses, with an ED50 of 9.7 mg/kg. The duration of analgesic effect was 60-90 min.

IC 50

COX-2: 0.34 μM (IC₅₀); COX-1: 1.3 μM (IC₅₀)

10,11-Dihydro-alpha-methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

10,11-Dihydro-alpha-methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid Suppliers

Global( 179)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hefei Lbao Physical & Chemical Science Co.,Ltd	+1-5184799099	lbaochemicals@gmail.com	China	317	58
Shanghai Arbor Chemical Co., Ltd.	021-60451682	act@arborchemical.com	CHINA	904	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29799	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32434	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	20342	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15142	58
Baoji Guokang Healthchem Co., Ltd.	+86-0917-3909592 +86-13892490616	gksales1@gk-bio.com	China	9233	58

Supplier	Advantage
Hefei Lbao Physical & Chemical Science Co.,Ltd	58
Shanghai Arbor Chemical Co., Ltd.	58
Hubei xin bonus chemical co. LTD	58
Alchem Pharmtech,Inc.	58
career henan chemical co	58
SIMAGCHEM CORP	58
TargetMol Chemicals Inc.	58
Dideu Industries Group Limited	58
AFINE CHEMICALS LIMITED	58
Baoji Guokang Healthchem Co., Ltd.	58

View Lastest Price from 10,11-Dihydro-alpha-methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-10-18	2-(10-Oxo-10,11-dihydrodibenzo[b,f]thiepin-2-yl)propanoic acid 74711-43-6	US $0.00 / kg	1kg	98%	Customise	Hefei Lbao Physical & Chemical Science Co.,Ltd
2025-10-15	Zaltoprofen 74711-43-6	US $34.00-68.00 / mg		99.72%	10g	TargetMol Chemicals Inc.
2022-02-18	Zaltoprofen 74711-43-6	US $0.00 / gram	1gram	99%	10kg	Zhejiang J&C Biological Technology Co.,Limited

2-(10-Oxo-10,11-dihydrodibenzo[b,f]thiepin-2-yl)propanoic acid
74711-43-6
US $0.00 / kg
98%
Hefei Lbao Physical & Chemical Science Co.,Ltd

Zaltoprofen
74711-43-6
US $34.00-68.00 / mg
99.72%
TargetMol Chemicals Inc.

Zaltoprofen
74711-43-6
US $0.00 / gram
99%
Zhejiang J&C Biological Technology Co.,Limited

10,11-Dihydro-alpha-methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid Spectrum

10,11-Dihydro-alpha-methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid(74711-43-6)¹HNMR

74711-43-6(10,11-Dihydro-alpha-methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid)Related Search:

Benztropine mesylate Pivalic acid Methyl salicylate Methyl 2,2-dimethylphenylacetate Tribenuron methyl

Ethyl 2-(Chlorosulfonyl)acetate 4-Methylphenylacetic acid Dihydromyrcenol Methanol Methyl acrylate

Dimethylbenzylcarbinyl acetate Ibuprofen Methylparaben Zaltoprofen Zalcitabine

Zafirlukast ZANAMIVIR HYDRATE N-Ethyl-N-3-((3-dimethylamino-1-oxo-2-propenyl)phenyl)acetamide

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2-(6-oxo-5H-benzo[b][1]benzothiepin-3-yl)propanoic acid Zaltoprofen/ 10,11-Dihydro-alpha-Methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid Zaltoprofen, >=99% Salafapinon Soleton Dibenzo(B,F)thiepin-2-acetic acid, 10,11-dihydro-alpha-methyl-10-oxo- Einecs 277-973-5 Zaltoprofen (unspecified) CAS No:74711-43-6 Dibenzo[b,f]thiepin-2-aceticacid, 10,11-dihydro-a-Methyl-10-oxo- 10,11-dihydro-alpha-methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid ZALTOPROFEN CN100;SOLETON;CN-100;CN 100 3-(10-Oxo-10,11-dihydrodibenzo[b,f]thiepin-2-yl)propanoic acid Dibenzo[b,f]Thiepin-2-Acetic Acid 2-(10-Oxo-10,11-dihydrodibenzo[b,f]thiepin-2-yl)propanoic acid 10,11-Dihydro-alpha-Methyl-10-oxo-dibenzo Dibenzo[b,f]thiepin-2-acetic acid, 10,11-dihydro-α-methyl-10-oxo- Dibenzo[b,f]thiepin-2-acetic acid, 10,11-dihydro-a-methyl-10-oxo- 10,11-dihydro-α-methyl-10-oxodibenzo[b,f]thiepin-2-acetic acid 10,11-Dihydro-alpha-methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid USP/EP/BP Zaltoprofen (CN100) ZaltoprofenQ: What is Zaltoprofen Q: What is the CAS Number of Zaltoprofen Q: What is the storage condition of Zaltoprofen Q: What are the applications of Zaltoprofen Zatobuprofen Zaltoprofen, 10 mM in DMSO Dibenzo[b,f]thiepin-2-acetic acid, 10,11-dihydro-α-methyl-10-oxo- Zaltoprofen: 2-(10,11-Dihydro-10-oxodibenzo[b,f]thiepin-2-yl)propionic Acid 74711-43-6 Inhibitors Zaltoprofen Intermediates & Fine Chemicals Pharmaceuticals