TEMAFLOXACIN
- CAS No.
- 108319-06-8
- Chemical Name:
- TEMAFLOXACIN
- Synonyms
- Teflox;A-63004;A-62254;Omniflox;AKOS 92085;TEMAFLOXACIN;TeMafloxacin HCl;TEMAFLOXACIN USP/EP/BP;Temafloxacin (Omniflox);6-Fluoro-1-(2,4-difluorophenyl)-7-(3-methylpiperazin-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
- CBNumber:
- CB4244763
- Molecular Formula:
- C21H18F3N3O3
- Molecular Weight:
- 417.38
- MDL Number:
- MFCD00864828
- MOL File:
- 108319-06-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | >200°C (dec.) |
|---|---|
| Boiling point | 608.9±55.0 °C(Predicted) |
| Density | 1.3372 (estimate) |
| storage temp. | 2-8°C(protect from light) |
| solubility | Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 6.02±0.41(Predicted) |
| color | White to Off-White |
| Stability | Hygroscopic |
| InChI | InChI=1S/C21H18F3N3O3/c1-11-9-26(5-4-25-11)19-8-18-13(7-16(19)24)20(28)14(21(29)30)10-27(18)17-3-2-12(22)6-15(17)23/h2-3,6-8,10-11,25H,4-5,9H2,1H3,(H,29,30) |
| InChIKey | QKDHBVNJCZBTMR-UHFFFAOYSA-N |
| SMILES | N1(C2=CC=C(F)C=C2F)C2=C(C=C(F)C(N3CCNC(C)C3)=C2)C(=O)C(C(O)=O)=C1 |
| FDA UNII | 1WZ12GTT67 |
| ATC code | J01MA05 |
TEMAFLOXACIN price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17352 | Temafloxacin ≥95% | 108319-06-8 | 1mg | $49 | 2026-04-30 | Buy |
| Cayman Chemical | 17352 | Temafloxacin ≥95% | 108319-06-8 | 5mg | $130 | 2026-04-30 | Buy |
| Cayman Chemical | 17352 | Temafloxacin ≥95% | 108319-06-8 | 10mg | $213 | 2026-04-30 | Buy |
| Cayman Chemical | 17352 | Temafloxacin ≥95% | 108319-06-8 | 25mg | $354 | 2026-04-30 | Buy |
| Usbiological | 290570 | Temafloxacin Asreported | 108319-06-8 | 10mg | $562 | 2026-06-03 | Buy |
TEMAFLOXACIN Chemical Properties, Uses, Production
Description
Temafloxacin is a fluoroquinolone antibiotic that acts as a DNA topoisomerase inhibitor. It has broad antimicrobial activity against gram-positive and gram-negative bacteria, such as S. pneumoniae, M. hominis, and anaerobic bacteria, including B. fragilis.
Chemical Properties
Crystallizes in ethanol, melting point 274-276℃.
Uses
Antibacterial (microbial DNA topoisomerase inhibitor).
Uses
Temafloxacin is an antimicrobial quinolone drug.
Definition
ChEBI: 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a quinolone that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted at positions 1, 6, and 7 by 2,4-difluorophenyl, fluorine, and 3-methylpiperazin-1-yl groups, respectively. It is a quinolone, an amino acid, a monocarboxylic acid, an organofluorine compound, a secondary amino compound, a tertiary amino compound, a N-arylpiperazine and a quinolone antibiotic.
brand name
Omniflox (Abbott);8Omniflox 8Teflox 8Temac.
World Health Organization (WHO)
Temafloxacin, a quinolone antimicrobial, was introduced in 1991. Shortly afterwards, its use became associated with severe adverse effects, including hypoglycaemia, haemolytic anaemia, renal failure, hepatitis and anaphylactic reactions. This led to its worldwide withdrawal by the manufacturer.
References
[1] M.D. G A P. Temafloxacin: An overview[J]. American Journal of Medicine, 1991, 91 6: Pages S166-S172. DOI: 10.1016/0002-9343(91)90332-r
TEMAFLOXACIN Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hekang Biotechnology Co., Ltd. | 17721021104 18939837085 | 2880152141@qq.com | China | 1840 | 55 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
| CEG Chemical Science&Technology Co., Ltd. | Mobile:13665161512 | China | 1784 | 58 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Finetech Industry Limited | 027-87465837 19945049750 | sales@finetechnology-ind.com | China | 9331 | 58 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9909 | 65 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| UHN Shanghai Research & Development Co., Ltd. | 021-58958002 18930822973 | sales@uhnshanghai.com | China | 1983 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
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- Mar 25,2022
View Latest Price from TEMAFLOXACIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | TEMAFLOXACIN USP/EP/BP
108319-06-8
|
$1.10 | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | |
 |
2026-05-11 | Temafloxacin
108319-06-8
|
$34.00-80.00 | 99.24% | 10g | TargetMol Chemicals Inc. |
-
- TEMAFLOXACIN USP/EP/BP
108319-06-8
- $1.10
- 99.9%
- Dideu Industries Group Limited
-
- Temafloxacin
108319-06-8
- $34.00-80.00
- 99.24%
- TargetMol Chemicals Inc.
