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6-Chloro-5-(trifluoromethyl)pyridin-3-amine

CAS No.
99368-68-0
Chemical Name:
6-Chloro-5-(trifluoromethyl)pyridin-3-amine
Synonyms
6-Chloro-5-(trifluoromethyl);6-Chloro-5-(trifluoromethyl)pyridin-3-amine;6-chloro-5-(trifluoromethyl)-3-Pyridinamine;6-Chloro-5-trifluoroMethyl-pyridin-3-ylaMine;3-Amino-6-chloro-5-(trifluoromethyl)pyridine;3-Pyridinamine, 6-chloro-5-(trifluoromethyl)-;6-chloro-5-(trifluoromethyl)pyridin-3-amine - [C27002]
CBNumber:
CB42455918
Molecular Formula:
C6H4ClF3N2
Molecular Weight:
196.56
MDL Number:
MFCD11101042
MOL File:
99368-68-0.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:40

6-Chloro-5-(trifluoromethyl)pyridin-3-amine Properties

Boiling point 292℃
Density 1.507
Flash point 130℃
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
Appearance Light yellow to light brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H335-H315-H319
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
HS Code  2933599590

6-Chloro-5-(trifluoromethyl)pyridin-3-amine price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC201388 6-Chloro-5-(trifluoromethyl)pyridin-3-amine 98% 99368-68-0 100mg $21 2026-06-04 Buy
Apolloscientific PC201388 6-Chloro-5-(trifluoromethyl)pyridin-3-amine 98% 99368-68-0 250mg $24 2026-06-04 Buy
Apolloscientific PC201388 6-Chloro-5-(trifluoromethyl)pyridin-3-amine 98% 99368-68-0 1g $51 2026-06-04 Buy
Apolloscientific PC201388 6-Chloro-5-(trifluoromethyl)pyridin-3-amine 98% 99368-68-0 5g $244 2026-06-04 Buy
Apolloscientific PC201388 6-Chloro-5-(trifluoromethyl)pyridin-3-amine 98% 99368-68-0 25g $1136 2026-06-04 Buy
Product number Packaging Price Buy
PC201388 100mg $21 Buy
PC201388 250mg $24 Buy
PC201388 1g $51 Buy
PC201388 5g $244 Buy
PC201388 25g $1136 Buy

6-Chloro-5-(trifluoromethyl)pyridin-3-amine Chemical Properties, Uses, Production

Synthesis

2-CHLORO-5-NITRO-3-(TRIFLUOROMETHYL)PYRIDINE

99368-67-9

6-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE

99368-68-0

A solution of 5% Pt/C (1.58 mmol, 0.31 g) in ethyl acetate (50 mL) was added to 2-chloro-5-nitro-3-(trifluoromethyl)pyridine (5.25 mmol, 1.19 g) mixed with ZnBr2 (1.05 mmol, 0.200 g) and the reaction was stirred for 20 hrs under hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration and the solid was washed with warm ethanol. The solvent was evaporated to afford the target product 6-chloro-5-(trifluoromethyl)pyridin-3-amine (0.95 g, 92% yield). The product was characterized by 1H NMR (300 MHz, DMSO-d6): δ 5.59 (bs, 1H), 7.37 (s, 1H), 7.92 (s, 1H).

References

[1] Patent: WO2018/20474, 2018, A1. Location in patent: Page/Page column 309-310
[2] Patent: WO2009/21696, 2009, A1. Location in patent: Page/Page column 38; 69-70
[3] Patent: US2007/60623, 2007, A1. Location in patent: Page/Page column 39
[4] Patent: US2014/275111, 2014, A1. Location in patent: Paragraph 0280; 0281
[5] Patent: WO2014/141187, 2014, A1. Location in patent: Page/Page column 60

6-Chloro-5-(trifluoromethyl)pyridin-3-amine Preparation Products And Raw materials

Global Suppliers ( 84)
Supplier Tel Email Country ProdList Advantage
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 0311-89250318 13582355795 master@sjzsdyn.com China 2776 65
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9509 58
Shanghai Famo Bio-chemical Technology Company Ltd. 021-36680027 15821745250 fengqiang@famobiotech.com China 494 56
Shanghai Keepontech Co.,Ltd 021-54849683 13601642561 sales@keepontech.com China 998 59
Cochemical Ltd. 029-86115547 17791676824 sales@cochemical.com China 3014 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai AQBioPharma Co., Ltd. 13661411401 yinglv.que@aqbiopharma.com.cn China 2976 58
Tianjin Anhao Biological Technology Co., Ltd. sales@ahpharmatech.com China 5734 55
Struchem Co., Ltd. 0512-63009836 18994340901 helen@struchem.com China 3968 60
SuZhou ShiYa Biopharmaceuticals, Inc. 0512-0512-52358471 17715136450 sales@shiyabiopharm.com China 9814 58

View Latest Price from 6-Chloro-5-(trifluoromethyl)pyridin-3-amine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE pictures 2019-07-06 6-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE
99368-68-0
$1.00 1G 99% 100KG Career Henan Chemical Co
6-Chloro-5-trifluoroMethyl-pyridin-3-ylaMine 6-chloro-5-(trifluoromethyl)-3-Pyridinamine 6-Chloro-5-(trifluoromethyl) 3-Pyridinamine, 6-chloro-5-(trifluoromethyl)- 3-Amino-6-chloro-5-(trifluoromethyl)pyridine 6-chloro-5-(trifluoromethyl)pyridin-3-amine - [C27002] 6-Chloro-5-(trifluoromethyl)pyridin-3-amine 99368-68-0