6-Chloro-5-(trifluoromethyl)pyridin-3-amine
- CAS No.
- 99368-68-0
- Chemical Name:
- 6-Chloro-5-(trifluoromethyl)pyridin-3-amine
- Synonyms
- 6-Chloro-5-(trifluoromethyl);6-Chloro-5-(trifluoromethyl)pyridin-3-amine;6-chloro-5-(trifluoromethyl)-3-Pyridinamine;6-Chloro-5-trifluoroMethyl-pyridin-3-ylaMine;3-Amino-6-chloro-5-(trifluoromethyl)pyridine;3-Pyridinamine, 6-chloro-5-(trifluoromethyl)-;6-chloro-5-(trifluoromethyl)pyridin-3-amine - [C27002]
- CBNumber:
- CB42455918
- Molecular Formula:
- C6H4ClF3N2
- Molecular Weight:
- 196.56
- MDL Number:
- MFCD11101042
- MOL File:
- 99368-68-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| HS Code | 2933599590 |
6-Chloro-5-(trifluoromethyl)pyridin-3-amine price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC201388 | 6-Chloro-5-(trifluoromethyl)pyridin-3-amine 98% | 99368-68-0 | 100mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC201388 | 6-Chloro-5-(trifluoromethyl)pyridin-3-amine 98% | 99368-68-0 | 250mg | $24 | 2026-06-04 | Buy |
| Apolloscientific | PC201388 | 6-Chloro-5-(trifluoromethyl)pyridin-3-amine 98% | 99368-68-0 | 1g | $51 | 2026-06-04 | Buy |
| Apolloscientific | PC201388 | 6-Chloro-5-(trifluoromethyl)pyridin-3-amine 98% | 99368-68-0 | 5g | $244 | 2026-06-04 | Buy |
| Apolloscientific | PC201388 | 6-Chloro-5-(trifluoromethyl)pyridin-3-amine 98% | 99368-68-0 | 25g | $1136 | 2026-06-04 | Buy |
6-Chloro-5-(trifluoromethyl)pyridin-3-amine Chemical Properties, Uses, Production
Synthesis
99368-67-9
99368-68-0
A solution of 5% Pt/C (1.58 mmol, 0.31 g) in ethyl acetate (50 mL) was added to 2-chloro-5-nitro-3-(trifluoromethyl)pyridine (5.25 mmol, 1.19 g) mixed with ZnBr2 (1.05 mmol, 0.200 g) and the reaction was stirred for 20 hrs under hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration and the solid was washed with warm ethanol. The solvent was evaporated to afford the target product 6-chloro-5-(trifluoromethyl)pyridin-3-amine (0.95 g, 92% yield). The product was characterized by 1H NMR (300 MHz, DMSO-d6): δ 5.59 (bs, 1H), 7.37 (s, 1H), 7.92 (s, 1H).
References
[1] Patent: WO2018/20474, 2018, A1. Location in patent: Page/Page column 309-310
[2] Patent: WO2009/21696, 2009, A1. Location in patent: Page/Page column 38; 69-70
[3] Patent: US2007/60623, 2007, A1. Location in patent: Page/Page column 39
[4] Patent: US2014/275111, 2014, A1. Location in patent: Paragraph 0280; 0281
[5] Patent: WO2014/141187, 2014, A1. Location in patent: Page/Page column 60
6-Chloro-5-(trifluoromethyl)pyridin-3-amine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9509 | 58 |
| Shanghai Famo Bio-chemical Technology Company Ltd. | 021-36680027 15821745250 | fengqiang@famobiotech.com | China | 494 | 56 |
| Shanghai Keepontech Co.,Ltd | 021-54849683 13601642561 | sales@keepontech.com | China | 998 | 59 |
| Cochemical Ltd. | 029-86115547 17791676824 | sales@cochemical.com | China | 3014 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai AQBioPharma Co., Ltd. | 13661411401 | yinglv.que@aqbiopharma.com.cn | China | 2976 | 58 |
| Tianjin Anhao Biological Technology Co., Ltd. | sales@ahpharmatech.com | China | 5734 | 55 | |
| Struchem Co., Ltd. | 0512-63009836 18994340901 | helen@struchem.com | China | 3968 | 60 |
| SuZhou ShiYa Biopharmaceuticals, Inc. | 0512-0512-52358471 17715136450 | sales@shiyabiopharm.com | China | 9814 | 58 |
View Latest Price from 6-Chloro-5-(trifluoromethyl)pyridin-3-amine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2019-07-06 | 6-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE
99368-68-0
|
$1.00 | 1G | 99% | 100KG | Career Henan Chemical Co |
-

- 6-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE
99368-68-0
- $1.00
- 99%
- Career Henan Chemical Co
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