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ChemicalBook >> CAS DataBase List >>1-(Benzyloxy)-4-bromo-2-methoxybenzene

1-(Benzyloxy)-4-bromo-2-methoxybenzene

1-(Benzyloxy)-4-bromo-2-methoxybenzene Structure
1-(Benzyloxy)-4-bromo-2-methoxybenzene structure
CAS No.
63057-72-7
Chemical Name:
1-(Benzyloxy)-4-bromo-2-methoxybenzene
Synonyms
2-(Benzyloxy)-5-bromoanisole;4-Bromo-2-methoxy-1-phenylmethoxybenzene;Benzene, 4-bromo-2-methoxy-1-(phenylmethoxy)-
CBNumber:
CB42456692
Molecular Formula:
C14H13BrO2
Molecular Weight:
293.16
MDL Number:
MFCD00092521
MOL File:
63057-72-7.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:40
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1-(Benzyloxy)-4-bromo-2-methoxybenzene Properties

storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Environment (GHS09)Corrosion (GHS05)
GHS07,GHS09,GHS05
Signal word  Danger
Hazard statements  H315-H318-H335-H410
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P280-P305+P351+P338-P310-P273-P391-P501

1-(Benzyloxy)-4-bromo-2-methoxybenzene price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S813834 1-(BENZYLOXY)-4-BROMO-2-METHOXYBENZENE AldrichCPR 63057-72-7 1 unit $32.7 2026-04-30 Buy
Sigma-Aldrich S813834 1-(BENZYLOXY)-4-BROMO-2-METHOXYBENZENE Aldrich 63057-72-7 5mg $29.8 2024-03-01 Buy
TRC TRC-B291493-500MG 1-(Benzyloxy)-4-bromo-2-methoxybenzene 63057-72-7 500mg $84 2026-06-03 Buy
TRC TRC-B291493-250MG 1-(Benzyloxy)-4-bromo-2-methoxybenzene 63057-72-7 250mg $72 2026-06-03 Buy
TRC TRC-B291493-100MG 1-(Benzyloxy)-4-bromo-2-methoxybenzene 63057-72-7 100mg $65 2026-06-03 Buy
Product number Packaging Price Buy
S813834 1 unit $32.7 Buy
S813834 5mg $29.8 Buy
TRC-B291493-500MG 500mg $84 Buy
TRC-B291493-250MG 250mg $72 Buy
TRC-B291493-100MG 100mg $65 Buy

1-(Benzyloxy)-4-bromo-2-methoxybenzene Chemical Properties, Uses, Production

Synthesis

4-Bromo-2-methoxyphenol

7368-78-7

Benzyl bromide

100-39-0

1-(BENZYLOXY)-4-BROMO-2-METHOXYBENZENE

63057-72-7

Step 1: Synthesis of 1-(benzyloxy)-4-bromo-2-methoxybenzene (2). Potassium carbonate (K2CO3, 30.5 g, 221 mmol) and benzyl bromide (18.9 g, 171 mmol) were added to a solution of N,N-dimethylformamide (DMF, 150 mL) containing 4-bromo-2-methoxyphenol (15 g, 73.8 mmol). The reaction mixture was stirred at 100 °C for 2 hours. Upon completion of the reaction, the reaction was quenched by the addition of water and the organic layer was extracted with ethyl acetate (EtOAc). The organic phases were combined and concentrated. The crude product was purified by column chromatography to afford the target compound 2 (17.6 g, 86% yield).

References

[1] Patent: US2005/43300, 2005, A1. Location in patent: Page/Page column 39
[2] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 14, p. 2793 - 2799
[3] Journal of Organic Chemistry, 2002, vol. 67, # 10, p. 3425 - 3436
[4] Patent: WO2018/64557, 2018, A1. Location in patent: Paragraph 0444; 0445; 0446; 0447
[5] Patent: US2006/264473, 2006, A1. Location in patent: Page/Page column 5

1-(Benzyloxy)-4-bromo-2-methoxybenzene synthesis

7368-78-7
100-39-0
63057-72-7
Synthesis of 1-(Benzyloxy)-4-bromo-2-methoxybenzene from 4-Bromo-2-methoxyphenol and Benzyl bromide

1-(Benzyloxy)-4-bromo-2-methoxybenzene Preparation Products And Raw materials

Raw materials

4-Bromo-2-methoxyphenol Benzyl bromide N,N-Dimethylformamide Potassium carbonate

Preparation Products

1-(Benzyloxy)-4-bromo-2-methoxybenzene Suppliers

Global Suppliers ( 50)
Supplier Tel Email Country ProdList Advantage
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29977 65
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai ShiXian Chemical Technology Co., Ltd. 13764359345 990877971@qq.com China 1921 50
Wuhan Chemwish Technology Co.， Ltd 027-67849912 sales@chemwish.com China 9144 60
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai SuperLan Chemcial Technique Centre 0-2022843681 15618226720 chaolaichem@foxmail.com China 9996 58
Supplier Advantage
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 55
9ding chemical ( Shanghai) Limited 56
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
Bide Pharmatech Ltd. 60
Shanghai ShiXian Chemical Technology Co., Ltd. 50
Wuhan Chemwish Technology Co.， Ltd 60
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai SuperLan Chemcial Technique Centre 58

1-(Benzyloxy)-4-bromo-2-methoxybenzene Spectrum

1-(BENZYLOXY)-4-BROMO-2-METHOXYBENZENE(63057-72-7)1HNMR

63057-72-7 (1-(Benzyloxy)-4-bromo-2-methoxybenzene) Related Search:

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Benzene, 4-bromo-2-methoxy-1-(phenylmethoxy)- 4-Bromo-2-methoxy-1-phenylmethoxybenzene 2-(Benzyloxy)-5-bromoanisole 63057-72-7