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Ethyl 6-chloro-2-pyridinecarboxylate

CAS No.
21190-89-6
Chemical Name:
Ethyl 6-chloro-2-pyridinecarboxylate
Synonyms
ethyl 6-chloropyridine-2-carboxylate;6-Chloropyridin-2-carboxylic acid ethyl ester;6-chloro-2-Pyridinecarboxylic acid ethyl ester;6-Chloropyridine-2-carboxylic acid ethyl ester;2-Pyridinecarboxylic acid, 6-chloro-, ethyl ester;6-chloro-2-Pyridinecarboxylic acid ethyl ester (9CI ACI);2-Pyridinecarboxylic acid, 6-chloro-, ethyl ester (9CI, ACI)
CBNumber:
CB42460981
Molecular Formula:
C8H8ClNO2
Molecular Weight:
185.61
MDL Number:
MFCD09878438
MOL File:
21190-89-6.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:40

Ethyl 6-chloro-2-pyridinecarboxylate Properties

Boiling point 289℃
Density 1.245
Flash point 129℃
storage temp. Store at room temperature
form Crystalline
pka -0.89±0.10(Predicted)
color Pale yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
HS Code  2933399990
NFPA 704
0
2 0

Ethyl 6-chloro-2-pyridinecarboxylate price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR901965 Ethyl 6-chloropicolinate 98% 21190-89-6 5g $21 2026-06-04 Buy
Apolloscientific OR901965 Ethyl 6-chloropicolinate 98% 21190-89-6 25g $36 2026-06-04 Buy
Apolloscientific OR901965 Ethyl 6-chloropicolinate 98% 21190-89-6 100g $124 2026-06-04 Buy
Apolloscientific OR901965 Ethyl 6-chloropicolinate 98% 21190-89-6 500g $603 2026-06-04 Buy
Matrix Scientific 119585 Ethyl 6-chloropicolinate 21190-89-6 5.00g $122 2026-05-18 Buy
Product number Packaging Price Buy
OR901965 5g $21 Buy
OR901965 25g $36 Buy
OR901965 100g $124 Buy
OR901965 500g $603 Buy
119585 5.00g $122 Buy

Ethyl 6-chloro-2-pyridinecarboxylate Chemical Properties, Uses, Production

Synthesis

6-Chloropicolinic acid

4684-94-0

Ethanol

64-17-5

ETHYL 6-CHLORO-2-PYRIDINECARBOXYLATE

21190-89-6

Step D: Preparation of ethyl 6-chloro-2-pyridinecarboxylate: 6-chloro-2-pyridinecarboxylic acid (23.5 g, 149 mmol), anhydrous ethanol (100 mL), and toluene (400 mL) were added to a round-bottomed flask equipped with a condenser. Concentrated sulfuric acid (4 mL) was slowly added to the reaction system, followed by heating the mixture to reflux and maintaining the reaction for 3 hours. Upon completion of the reaction, the mixture was cooled to room temperature. The solvent was removed by distillation under reduced pressure and the resulting oily product was dissolved in ethyl acetate (200 mL), washed with 10% aqueous potassium carbonate and dried over anhydrous sodium sulfate. Finally, the dried organic phase was concentrated under reduced pressure to afford ethyl 6-chloro-2-pyridinecarboxylate (26 g, 94% yield).

References

[1] Patent: WO2012/82689, 2012, A1. Location in patent: Page/Page column 56
[2] European Journal of Organic Chemistry, 2014, vol. 2014, # 28, p. 6295 - 6302
[3] Organic Letters, 2014, vol. 16, # 15, p. 3860 - 3863

Ethyl 6-chloro-2-pyridinecarboxylate Preparation Products And Raw materials

Global Suppliers ( 111)
Supplier Tel Email Country ProdList Advantage
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16306 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Nanjing Chemrui Pharmtech Co., Ltd. 86-25-58849758 13851795789 sales@chemrui.com China 47 62
Shanghai ZaiQi Bio-Tech Co., Ltd. 021-54824098, 021-37212705 021-37212706, 13391256916 sales@chemzq.com China 569 55
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
SuZhou ShiYa Biopharmaceuticals, Inc. 86(512)5235 8471 17715136450 sales@shiyabiopharm.com China 4167 58

View Latest Price from Ethyl 6-chloro-2-pyridinecarboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
	ETHYL 6-CHLORO-2-PYRIDINECARBOXYLATE pictures 2026-09-02 ETHYL 6-CHLORO-2-PYRIDINECARBOXYLATE
21190-89-6
$5.00 1KG 98% Henan Fengda Chemical Co., Ltd
ETHYL 6-CHLORO-2-PYRIDINECARBOXYLATE pictures 2026-06-30 ETHYL 6-CHLORO-2-PYRIDINECARBOXYLATE
21190-89-6
1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
ETHYL 6-CHLORO-2-PYRIDINECARBOXYLATE pictures 2020-01-09 ETHYL 6-CHLORO-2-PYRIDINECARBOXYLATE
21190-89-6
$2.00 1g 98%min Career Henan Chemical Co

Ethyl 6-chloro-2-pyridinecarboxylate Spectrum

6-Chloropyridine-2-carboxylic acid ethyl ester 2-Pyridinecarboxylic acid, 6-chloro-, ethyl ester 2-Pyridinecarboxylic acid, 6-chloro-, ethyl ester (9CI, ACI) 6-chloro-2-Pyridinecarboxylic acid ethyl ester (9CI ACI) 6-Chloropyridin-2-carboxylic acid ethyl ester 6-chloro-2-Pyridinecarboxylic acid ethyl ester ethyl 6-chloropyridine-2-carboxylate 21190-89-6