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2-Pyrimidinamine, 5-bromo-4-chloro-6-methyl-

CAS No.
6314-12-1
Chemical Name:
2-Pyrimidinamine, 5-bromo-4-chloro-6-methyl-
Synonyms
NSC 40200;5-Bromo-4-chloro-6-methylpyrimidin-2-amine;5-Bromo-4-chloro-6-methyl-2-pyrimidinamine;2-Amino-5-bromo-4-chloro-6-methylpyrimidine;2-Pyrimidinamine, 5-bromo-4-chloro-6-methyl-;2-PYRIMIDINAMINE, 5-BROMO-4-CHLORO-6-METHYL- ISO 9001:2015 REACH
CBNumber:
CB42463593
Molecular Formula:
C5H5BrClN3
Molecular Weight:
222.47
MDL Number:
MFCD00275421
MOL File:
6314-12-1.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:40

2-Pyrimidinamine, 5-bromo-4-chloro-6-methyl- Properties

Density 1.815
storage temp. -20°C, sealed storage, away from moisture and light
Appearance Off-white to light brown Solid
FDA UNII E6BZ3WQQ7G

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338

2-Pyrimidinamine, 5-bromo-4-chloro-6-methyl- price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FB144130 5-Bromo-4-chloro-6-methylpyrimidin-2-amine 6314-12-1 5g $900 2026-06-04 Buy
Biosynth FB144130 5-Bromo-4-chloro-6-methylpyrimidin-2-amine 6314-12-1 2g $900 2026-06-04 Buy
Biosynth FB144130 5-Bromo-4-chloro-6-methylpyrimidin-2-amine 6314-12-1 1g $900 2026-06-04 Buy
Biosynth FB144130 5-Bromo-4-chloro-6-methylpyrimidin-2-amine 6314-12-1 0.5g $900 2026-06-04 Buy
Biosynth FB144130 5-Bromo-4-chloro-6-methylpyrimidin-2-amine 6314-12-1 0.25g $900 2026-06-04 Buy
Product number Packaging Price Buy
FB144130 5g $900 Buy
FB144130 2g $900 Buy
FB144130 1g $900 Buy
FB144130 0.5g $900 Buy
FB144130 0.25g $900 Buy

2-Pyrimidinamine, 5-bromo-4-chloro-6-methyl- Chemical Properties, Uses, Production

Synthesis

2-Amino-4-chloro-6-methylpyrimidine

5600-21-5

2-PYRIMIDINAMINE, 5-BROMO-4-CHLORO-6-METHYL-

6314-12-1

The general procedure for the synthesis of 5-bromo-4-chloro-6-methyl-2-pyrimidinamine from 2-amino-4-chloro-6-methylpyrimidine is as follows: Example 6: Synthesis of 5-bromo-4-chloro-6-methylpyrimidin-2-amine 1. To a solution of 2-amino-4-chloro-6-methylpyrimidine (5.00 g, 34.8 mmol) in dichloromethane (240 mL) was slowly added bromine (1.88 mL, 36.6 mmol). 2. The reaction mixture was stirred at room temperature for 1.5 hours to form a suspension. 3. After the reaction was complete, the reaction mixture was diluted with dichloromethane (1.3 L). 4. The organic phase was washed sequentially with saturated sodium bicarbonate solution (2 x 200 mL) and brine (200 mL). 5. The organic layer was dried with anhydrous magnesium sulfate, filtered and concentrated to give 5-bromo-4-chloro-6-methylpyrimidin-2-amine (7.5 g, 97% yield). Product Characterization: LCMS (M + H): 223 1H NMR (400 MHz, chloroform-d) δ ppm: 2.54 (s, 3H), 5.10 (s, 2H)

References

[1] Patent: WO2008/32162, 2008, A1. Location in patent: Page/Page column 62-63
[2] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 15, p. 5098 - 5103
[3] Journal of Medicinal Chemistry, 2016, vol. 59, # 17, p. 8082 - 8093
[4] Patent: US2018/215720, 2018, A1. Location in patent: Paragraph 0057; 0059; 0074
[5] Bioorganic and Medicinal Chemistry, 2018, vol. 26, # 3, p. 637 - 646

2-Pyrimidinamine, 5-bromo-4-chloro-6-methyl- Preparation Products And Raw materials

2-Pyrimidinamine, 5-bromo-4-chloro-6-methyl- Suppliers

Global Suppliers ( 59)
Supplier Tel Email Country ProdList Advantage
China Langchem Inc. 0086-21-58956006 China 7798 57
Shanghai yirong biology science and technology co., ltd 18049974220 3060526242@qq.com China 999 60
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29977 65
SynAsst Chemical. 021-60343070 China 12731 55
Shanghai Apichemical CO.,LTD 021-51370612; info@apichemical.com China 242 60
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Zhengzhou Alfachem Co., Ltd. 0371-53765687 18937137882 3969243885@qq.com China 7734 55
Jiaxing Rich Biological Technology Co., Ltd. 0573-11111111-1111 18969316891 richmol@163.com China 450 50
Yancheng KangdiSen Pharmaceutical Co., Ltd. 13812573443;18052965989 tongbenwan22@163.com China 1975 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60

View Latest Price from 2-Pyrimidinamine, 5-bromo-4-chloro-6-methyl- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-PYRIMIDINAMINE, 5-BROMO-4-CHLORO-6-METHYL-  pictures 2026-08-20 2-PYRIMIDINAMINE, 5-BROMO-4-CHLORO-6-METHYL-
6314-12-1
$1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited

2-Pyrimidinamine, 5-bromo-4-chloro-6-methyl- Spectrum

5-Bromo-4-chloro-6-methylpyrimidin-2-amine 2-Amino-5-bromo-4-chloro-6-methylpyrimidine 5-Bromo-4-chloro-6-methyl-2-pyrimidinamine NSC 40200 2-PYRIMIDINAMINE, 5-BROMO-4-CHLORO-6-METHYL- ISO 9001:2015 REACH 2-Pyrimidinamine, 5-bromo-4-chloro-6-methyl- 6314-12-1 C5H5BrClN3