2-Amino-5-bromopyrimidine
- CAS No.
- 7752-82-1
- Chemical Name:
- 2-Amino-5-bromopyrimidine
- Synonyms
- 5-BROMOPYRIMIDIN-2-AMINE;5-BROMO-2-AMINOPYRIMIDINE;RUNA811;NSC 27269;TIMTEC-BB SBB000184;2-Amino-5-bromopyrimide;5-BROMO-2-PYRIMIDINAMINE;5-Bromopyrimidine-2-amine;2-AMINO-5-BROMOPYRIMIDINE;2-Amino-5-Bormopyrimidine
- CBNumber:
- CB6289294
- Molecular Formula:
- C4H4BrN3
- Molecular Weight:
- 174
- MDL Number:
- MFCD00012341
- MOL File:
- 7752-82-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 241-243 °C (lit.) |
|---|---|
| Boiling point | 340.7±34.0 °C(Predicted) |
| Density | 1.844±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| form | Crystalline Powder, Crystals or Flakes |
| pka | 1.93±0.10(Predicted) |
| color | White to light beige |
| Water Solubility | Insoluble |
| InChI | InChI=1S/C4H4BrN3/c5-3-1-7-4(6)8-2-3/h1-2H,(H2,6,7,8) |
| InChIKey | UHRHPPKWXSNZLR-UHFFFAOYSA-N |
| SMILES | C1(N)=NC=C(Br)C=N1 |
| CAS DataBase Reference | 7752-82-1(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H319-H400 | |||||||||
| Precautionary statements | P264-P270-P273-P280-P301+P312-P305+P351+P338 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn,N,Xi | |||||||||
| Risk Statements | 22-36-50/53 | |||||||||
| Safety Statements | 26-60-61 | |||||||||
| RIDADR | UN 3077 9/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Harmful | |||||||||
| HazardClass | IRRITANT, IRRITANT-HARMFUL | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29335995 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 Eye Irrit. 2 |
|||||||||
| NFPA 704 |
|
2-Amino-5-bromopyrimidine price More Price(87)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 303526 | 2-Amino-5-bromopyrimidine 98% | 7752-82-1 | 1g | $27.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 303526 | 2-Amino-5-bromopyrimidine 98% | 7752-82-1 | 5g | $46.1 | 2026-04-30 | Buy |
| TCI Chemical | A1920 | 2-Amino-5-bromopyrimidine >98.0%(GC)(T) | 7752-82-1 | 5g | $41 | 2026-04-30 | Buy |
| TCI Chemical | A1920 | 2-Amino-5-bromopyrimidine >98.0%(GC)(T) | 7752-82-1 | 25g | $172 | 2026-04-30 | Buy |
| Usbiological | B2840 | 5-Bromo-2-aminopyrimidine | 10g | $425 | 2026-06-03 | Buy |
2-Amino-5-bromopyrimidine Chemical Properties,Uses,Production
Chemical Properties
Yellow Solid
Uses
2-Amino-5-bromopyrimidine was employed:
- in synthesis of pyridine, pyrimidine and pyridinone C-nucleoside phosphoramidites
- in synthesis of 2-phthalimido-5-bromopyrimidine
- as intermediate for the preparation of sulfanilamides and amino acids containing the pyrimidine ring system. The products are potential antiviral agents
General Description
Crystal structure of 2-amino-5-bromopyrimidine was studied.
Synthesis
The synthesis of 2-Amino-5-bromopyrimidine is as follows:The 2-aminopyrimidine (2.5g, 26.29mmol) was dissolved in acetonitrile (25mL) was added N- bromosuccinimide (4.6g, 27.9mmol) under ice-cooling, stirred in the dark overnight at room temperature. Recovery of the solvent under reduced pressure, washed with water (100 mL) was washed, filtered off with suction, and dried in vacuo to give a white solid. Yield: 97%.
storage
Store in cool, well ventilated area. Keep container tightly closed. Light sensitive. Store under argon.
References
[1] Journal of Organic Chemistry, 2012, vol. 77, # 16, p. 6908 - 6916
[2] European Journal of Organic Chemistry, 2018, vol. 2018, # 43, p. 5921 - 5934
[3] Patent: CN106588884, 2017, A. Location in patent: Paragraph 0210; 0214; 0215; 0216
[4] Synthesis, 2004, # 17, p. 2809 - 2812
[5] Chemical Communications, 2017, vol. 53, # 44, p. 5997 - 6000
2-Amino-5-bromopyrimidine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Hunan Caiya Biological Technology Co., Ltd | 15580017485 | 2036676503@qq.com | China | 91 | 58 |
| Nanjing Jubai Biomedical Technology Co., Ltd. | 13585203734 | info@jbzml.com | China | 200 | 58 |
| Shanghai Tuolei Chemical Reagents Co., Ltd. | 86-021-50318510 | China | 67 | 55 | |
| Nanbu County Chengxin Technology Co., Ltd. | 0838-5675166 15883665058 | nbcxkj@126.com | China | 956 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
View Lastest Price from 2-Amino-5-bromopyrimidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 5-Bromopyrimidin-2-amine
7752-82-1
|
$1.00-122.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-08-20 | 2-Amino-5-bromopyrimidine
7752-82-1
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2026-08-07 | 5-BroMo-2-aMino-pyriMidine | $1.00 | 1KG | 99% | 500 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- 5-Bromopyrimidin-2-amine
7752-82-1
- $1.00-122.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 2-Amino-5-bromopyrimidine
7752-82-1
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 5-BroMo-2-aMino-pyriMidine
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
