Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol

6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol

6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol Structure
6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol structure
CAS No.
7400-06-8
Chemical Name:
6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol
Synonyms
NSC 59250;Tofacitinib Impurity 203;6-Amino-5-(2,2-diethoxyethyl);6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol;6-amino-5-(2,2-diethoxyethyl)-1H-pyrimidin-4-one;6-AMino-5-(2,2-diethoxyethyl)-4(3H)-pyriMidinone;6-aMino-5-(2,2-diethoxyethyl)pyriMidin-4(3H)-one;4-amino-6-hydroxy-5-(2,2-diethoxyethyl)pyrimidine;4(3H)-PyriMidinone, 6-aMino-5-(2,2-diethoxyethyl)-;6-aMino-5-(2,2-diethoxyethyl)-1,4-dihydropyriMidin-4- one
CBNumber:
CB42470171
Molecular Formula:
C10H17N3O3
Molecular Weight:
227.26
MDL Number:
MFCD02094191
MOL File:
7400-06-8.mol
MSDS File:
SDS
Last updated:2026-05-28 01:28:06
Product description Number Pack Size Price
6-Amino-5(2,2-diethoxyethyl)-4-hydroxy pyrimidine FA17591 50mg $150
6-Amino-5(2,2-diethoxyethyl)-4-hydroxy pyrimidine FA17591 25mg $150
6-Amino-5(2,2-diethoxyethyl)-4-hydroxy pyrimidine FA17591 100mg $227
6-Amino-5(2,2-diethoxyethyl)-4-hydroxy pyrimidine FA17591 250mg $362.5
6-Amino-5(2,2-diethoxyethyl)-4-hydroxy pyrimidine FA17591 500mg $545
Request For Quotation

6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol Properties

Melting point 193-196°C
Boiling point 336.0±52.0 °C(Predicted)
Density 1.26±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Methanol (Slightly)
form Solid
pka 10.08±0.50(Predicted)
color Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FA17591 6-Amino-5(2,2-diethoxyethyl)-4-hydroxy pyrimidine 7400-06-8 50mg $150 2026-06-04 Buy
Biosynth FA17591 6-Amino-5(2,2-diethoxyethyl)-4-hydroxy pyrimidine 7400-06-8 25mg $150 2026-06-04 Buy
Biosynth FA17591 6-Amino-5(2,2-diethoxyethyl)-4-hydroxy pyrimidine 7400-06-8 100mg $227 2026-06-04 Buy
Biosynth FA17591 6-Amino-5(2,2-diethoxyethyl)-4-hydroxy pyrimidine 7400-06-8 250mg $362.5 2026-06-04 Buy
Biosynth FA17591 6-Amino-5(2,2-diethoxyethyl)-4-hydroxy pyrimidine 7400-06-8 500mg $545 2026-06-04 Buy
Product number Packaging Price Buy
FA17591 50mg $150 Buy
FA17591 25mg $150 Buy
FA17591 100mg $227 Buy
FA17591 250mg $362.5 Buy
FA17591 500mg $545 Buy

6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol Chemical Properties,Uses,Production

Chemical Properties

White Crystals With a Greenish Cast

Synthesis

6-AMINO-5(2,2-DIETHOXYETHYL)-4-HYDROXY-2-MERCAPTOPYRIMIDINE

7400-05-7

6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol

7400-06-8

Step i: 6-Amino-5-(2,2-diethoxyethyl)-2-mercapto-4-hydroxypyrimidine (11.6 mmol) [for preparation, see Davoll, J., J. Chem. Soc., 1960, pp131-138] was dissolved in a solvent mixture of water (150 mL) and aqueous ammonia solution (9 mL) and heated to 90°C. Raney Nickel suspension was added to the reaction mixture in batches (2-3 mL at a time) until TLC and LC/MS analysis showed that the reaction was complete. The reaction mixture was cooled to room temperature, filtered through a diatomaceous earth pad and the filter cake was washed with water (2 x 25 mL). The combined aqueous filtrates were freeze-dried to afford 6-amino-5-(2,2-diethoxyethyl)-4-hydroxypyrimidine as an off-white powder in a yield of 2.23 g (85%).LC/MS: RT = 1.37 min; m/z = 182 [M-EtOH + H]+ . Total run time was 3.75 min.1H NMR (DMSO-d6): δ 1.07 (t, 6H); 3.40 (m, 2H); 3.59 (m, 2H); 4.56 (t, 1H); 6.07 (br s, 2H); 7.70 (s, 1H); 11.43 (br s, 1H).

References

[1] Patent: WO2007/104944, 2007, A1. Location in patent: Page/Page column 43
[2] Patent: WO2006/46023, 2006, A1. Location in patent: Page/Page column 123
[3] Patent: WO2008/75109, 2008, A1. Location in patent: Page/Page column 112
[4] Patent: WO2006/46024, 2006, A1. Location in patent: Page/Page column 118
[5] Patent: WO2007/125321, 2007, A2. Location in patent: Page/Page column 116

6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol Preparation Products And Raw materials

Raw materials

6-AMINO-5(2,2-DIETHOXYETHYL)-4-HYDROXY-2-MERCAPTOPYRIMIDINE Ammonia

Preparation Products

4-CHLORO-7-((2-(TRIMETHYLSILYL)ETHOXY)METHYL)-7H-PYRROLO[2,3-D]PYRIMIDINE

6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol Suppliers

Global( 56)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29812 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11680 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42056 58
Aladdin Scientific 		tp@aladdinsci.com United States 52923 58
Moxin Chemicals 		+86-17320513646 +8617320513646 anna@molcoo.com China 10000 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39927 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131956 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Supplier Advantage
career henan chemical co 		58
Alchem Pharmtech,Inc. 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		58
Jilin Chinese Academy of Sciences-yanshen Technology 		58
Aladdin Scientific 		58
Moxin Chemicals 		58
Chongqing Chemdad Co., Ltd 		58
Amadis Chemical Company Limited 		58
J & K SCIENTIFIC LTD. 76

View Lastest Price from 6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol pictures 2019-07-10 6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol
7400-06-8
 $1.00 1KG 98% 150KG Career Henan Chemical Co

6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol Spectrum

6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol(7400-06-8)1HNMR

7400-06-8(6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol)Related Search:

Tofacitinib impurity T Methyl (4-Methylpiperidin-3-yl)carbaMate 4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine BENZYL ETHYL ETHER 4-chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine
N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Tofacitinib Impurity 85 N-((3R,4S)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine 4-Amino-2,6-dichloropyrimidine Malonyl chloride
Benzyl chloride 6-AMINO-5(2,2-DIETHOXYETHYL)-4-HYDROXY-2-MERCAPTOPYRIMIDINE 1-Benzyl-4-methyl-piperidin-3-one hydrochloride CYANOACETIC ACID-OSU N-Hydroxysuccinimide
Tofacitinib Impurity 29 N-Methyl-N-((3S,4S)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine Tofacitinib Impurity 19

1of4

6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol 6-aMino-5-(2,2-diethoxyethyl)pyriMidin-4(3H)-one 6-AMino-5-(2,2-diethoxyethyl)-4(3H)-pyriMidinone NSC 59250 4(3H)-PyriMidinone, 6-aMino-5-(2,2-diethoxyethyl)- 6-aMino-5-(2,2-diethoxyethyl)-1,4-dihydropyriMidin-4- one 6-amino-5-(2,2-diethoxyethyl)-1H-pyrimidin-4-one 6-Amino-5-(2,2-diethoxyethyl) Tofacitinib Impurity 203 4-amino-6-hydroxy-5-(2,2-diethoxyethyl)pyrimidine 7400-06-8 Amines Aromatics Bases & Related Reagents Heterocycles Intermediates Nucleotides