(1r,4r)-methyl 4-formylcyclohexanecarboxylate
- CAS No.
- 54274-80-5
- Chemical Name:
- (1r,4r)-methyl 4-formylcyclohexanecarboxylate
- Synonyms
- Methyl 4-forMylcyclohexanecarboxylate;(E)-Methyl 4-forMylcyclohexanecarboxylate;trans-Methyl 4-forMylcyclohexanecarboxylate;Methyl trans-4-forMylcyclohexanecarboxylate;(1r,4r)-methyl 4-formylcyclohexanecarboxylate;Methyl trans-4-formylcyclohexane-1-carboxylate;methyl(1r,4r)-4-formylcyclohexane-1-carboxylate;methyl Rel-(1r,4r)-4-formylcyclohexane-1-carboxylate;Itemname-(1R,4R)-Methyl4-formylcyclohexanecarboxylate;trans-4-formyl-cyclohexanecarboxylic acid methyl ester
- CBNumber:
- CB42489834
- Molecular Formula:
- C9H14O3
- Molecular Weight:
- 170.21
- MDL Number:
- MFCD12965033
- MOL File:
- 54274-80-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| HS Code | 2918300090 |
(1r,4r)-methyl 4-formylcyclohexanecarboxylate price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR928143 | Methyl trans-4-formylcyclohexanecarboxylate 96% | 54274-80-5 | 1g | $69 | 2026-06-04 | Buy |
| Apolloscientific | OR928143 | Methyl trans-4-formylcyclohexanecarboxylate 96% | 54274-80-5 | 5g | $251 | 2026-06-04 | Buy |
| Apolloscientific | OR928143 | Methyl trans-4-formylcyclohexanecarboxylate 96% | 54274-80-5 | 10g | $437 | 2026-06-04 | Buy |
| Matrix Scientific | 122574 | Methyl trans-4-formylcyclohexanecarboxylate | 54274-80-5 | 1.00g | $64 | 2026-05-18 | Buy |
| Matrix Scientific | 122574 | Methyl trans-4-formylcyclohexanecarboxylate | 54274-80-5 | 5.00g | $296 | 2026-05-18 | Buy |
(1r,4r)-methyl 4-formylcyclohexanecarboxylate Chemical Properties, Uses, Production
Synthesis
110928-44-4
54274-80-5
The general procedure for the synthesis of trans-methyl-4-(hydroxymethyl)cyclohexanecarboxylic acid from methyl trans-4-(hydroxymethyl)cyclohexanecarboxylate was as follows: oxalyl chloride (7.74 g, 61.0 mmol) was slowly added to an anhydrous dichloromethane (400 mL) solution of dimethyl sulfoxide (9.53 g, 122 mmol) at -78 °C. After removing the cooling bath, the reaction mixture was stirred at -50 °C for 5 min. Subsequently, a solution of methyl trans-4-hydroxymethyl-cyclohexanecarboxylate (8.75 g, 50.8 mmol) in dichloromethane (108 mL) was added at -65 °C. After continued stirring for 30 minutes, triethylamine (25.7 g, 254 mmol) was added. Fifteen minutes after the addition was complete, the cooling bath was removed. The reaction mixture was quenched with 1 M aqueous hydrochloric acid (152 mL, 152 mmol) at -10 °C. The organic and aqueous layers were separated, and the organic layer was washed sequentially with two parts of 250 mL of water and one part of 100 mL of brine, and then dried with anhydrous sodium sulfate. Finally, a yellow oily trans-methyl-4-formylcyclohexanecarboxylic acid (9.3 g, quantitative yield) was obtained by vacuum concentration, which could be used directly in the next reaction without further purification.MS m/e: 170 (M+).
References
[1] Patent: US2014/221350, 2014, A1. Location in patent: Paragraph 0168
[2] Patent: EP1772454, 2007, A1. Location in patent: Page/Page column 55-56
[3] Patent: WO2013/192088, 2013, A1. Location in patent: Paragraph 00216
[4] ChemMedChem, 2016, vol. 11, # 1, p. 31 - 37
(1r,4r)-methyl 4-formylcyclohexanecarboxylate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shijizhuang Zhoukun Pharmaceutical Technology Co., LTD | 0311-83784138 18633934202 | zhoukunpharma@163.com | China | 2420 | 58 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. | 21-57721279 18121011378 | sales@shydchem.com.cn | China | 998 | 56 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9509 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9335 | 55 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Shanghai Sheepchem Co., Ltd. | +86 (21) 6715-7650 | sheepchem@163.com | China | 993 | 60 |
View Latest Price from (1r,4r)-methyl 4-formylcyclohexanecarboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-16 | methyl trans-4-formylcyclohexanecarboxylate
54274-80-5
|
10gm | 96%min | 10kg | Shanghai Yongzeng Technology Co.,Ltd | ||
 |
2026-08-25 | Methyl4-formylcyclohexanecarboxylate
54274-80-5
|
$3.00-9.00 | 99% | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |||
 |
2021-04-08 | trans-4-formyl-cyclohexanecarboxylic acid methyl ester
54274-80-5
|
1g | 99% | 100KG/MONTH | Pharmahands (Taizhou) Co., Ltd. |
-
- methyl trans-4-formylcyclohexanecarboxylate
54274-80-5
- $0.00
- 96%min
- Shanghai Yongzeng Technology Co.,Ltd
-
- Methyl4-formylcyclohexanecarboxylate
54274-80-5
- $3.00-9.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- trans-4-formyl-cyclohexanecarboxylic acid methyl ester
54274-80-5
- 99%
- Pharmahands (Taizhou) Co., Ltd.
