1H-1-Ethyl Candesartan Cilexetil
- CAS No.
- 914613-35-7
- Chemical Name:
- 1H-1-Ethyl Candesartan Cilexetil
- Synonyms
- Candesartan Cilexetil EP IMpurity E;Candesartan EP Imp E;Candesartan Impurity 2;Candesartan EP Impurity-E;Candesartan Cilexetil impurity E;1H-1-Ethyl Candesartan Cilexetil;Candesartan Cilexetil Impurity 5(EP Impurity E);Candesartan Cilexetil Impurity 5(Candesartan Cilexetil EP Impurity E);2-Ethoxy-1-[[2'-(1-ethyl-1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-;Candesartan Cilexetil EP Impurity E (Candesartan Cilexetil N1-Ethyl Analog)
- CBNumber:
- CB42508599
- Molecular Formula:
- C35H38N6O6
- Molecular Weight:
- 638.71282
- MDL Number:
- MFCD18382323
- MOL File:
- 914613-35-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 1H-1-ethyl Candesartan Cilexetil ≥98% | 17912 | 1mg | $63 |
| 1H-1-ethyl Candesartan Cilexetil ≥98% | 17912 | 5mg | $242 |
| 1H-1-ethyl Candesartan Cilexetil ≥98% | 17912 | 10mg | $363 |
| 1H-1-Ethyl Candesartan Cilexetil >95%(HPLC) | TRC-E900870-10MG | 10mg | $256 |
| 1H-1-Ethyl Candesartan Cilexetil >95%(HPLC) | TRC-E900870-100MG | 100mg | $1931 |
| More product size | |||
| Melting point | 90-93°C |
|---|---|
| Boiling point | 842.0±75.0 °C(Predicted) |
| Density | 1.32 |
| storage temp. | Refrigerator |
| solubility | ≤30mg/ml in DMSO;30mg/ml in dimethyl formamide |
| form | crystalline solid |
| pka | 3.95±0.10(Predicted) |
| Major Application | pharmaceutical |
| InChIKey | HKUZPIFWPFYKBZ-UHFFFAOYSA-N |
| SMILES | C1(OCC)N(CC2=CC=C(C3=CC=CC=C3C3N(CC)N=NN=3)C=C2)C2=C(C(OC(OC(OC3CCCCC3)=O)C)=O)C=CC=C2N=1 |
| FDA UNII | IN72J7R432 |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
1H-1-Ethyl Candesartan Cilexetil price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17912 | 1H-1-ethyl Candesartan Cilexetil ≥98% | 914613-35-7 | 1mg | $63 | 2026-04-30 | Buy |
| Cayman Chemical | 17912 | 1H-1-ethyl Candesartan Cilexetil ≥98% | 914613-35-7 | 5mg | $242 | 2026-04-30 | Buy |
| Cayman Chemical | 17912 | 1H-1-ethyl Candesartan Cilexetil ≥98% | 914613-35-7 | 10mg | $363 | 2026-04-30 | Buy |
| TRC | TRC-E900870-10MG | 1H-1-Ethyl Candesartan Cilexetil >95%(HPLC) | 914613-35-7 | 10mg | $256 | 2026-06-03 | Buy |
| TRC | TRC-E900870-100MG | 1H-1-Ethyl Candesartan Cilexetil >95%(HPLC) | 914613-35-7 | 100mg | $1931 | 2026-06-03 | Buy |
1H-1-Ethyl Candesartan Cilexetil Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Candesartan Cilexetil Impurity E (PHARMEUROPA).
Biological Activity
1h-1-ethyl candesartan cilexetil, which is a process-related impurity commonly found in the bulk synthesis of candesartan cilexetil, is a potent, long-acting, and selective angiotensin ii type 1 receptor (at1) antagonist.angiotensin ii is a peptide that is mainly generated by the angiotensin converting enzyme and chymase, which plays a vital role in regulating blood pressure and sodium homeostasis via specific receptors including at1[1]. at1, localized in the kidney, heart, brain, adrenal gland, adipocytes, vascular smooth muscle cells, platelets, and placenta, is a major component of the renin-angiotensin system. furthermore, at1 mediates the classical biological actions of angiotensin ii. also, at1 has seven helical transmembrane domains, which is the characteristic of the superfamily of g-protein-coupled receptors. carboxyl-terminal region structure of at1 plays important roles in receptor internalization, desensitization and phosphorylation [2].
References
[1]. otsuka, m. reduction of bleomycin induced lung fibrosis by candesartan cilexetil, an angiotensin ii type 1 receptor antagonist. thorax. 2004; 59(1): 31-38.
[2]. guo, d., sun, y., hamet, p., & inagami, t. the angiotensin ii type 1 receptor and receptor-associated proteins. cell research. 2001; 11(3): 165-180.
1H-1-Ethyl Candesartan Cilexetil Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14320 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| CR Corporation Limited | fred.wen@crcorporation.cn | China | 8642 | 58 | |
| sgtlifesciences pvt ltd | +91-8790379245 | dj@sgtlifesciences.com | China | 12351 | 58 |
| ShenZhen H&D Pharmaceutical Technology Co., LTD | +86-18627948422 | sale@hdimpurity.com | China | 3676 | 58 |
| Pure Research Chemicals | +86-13564847951 +86-18019592524 | info@purerechem.com | China | 1000 | 58 |
| QUALITY CONTROL SOLUTIONS LTD. | +86-0755-66853366 +8613670046396 | export03@qcsrm.com | China | 24318 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
View Lastest Price from 1H-1-Ethyl Candesartan Cilexetil manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-08 | 1H-1-ethyl Candesartan Cilexetil
914613-35-7
|
$37.00-119.00 | 98.19% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-03-12 | Candesartan Cilexetil EP Impurity E
914613-35-7
|
10mg | 0.98 | 10g | ShenZhen H&D Pharmaceutical Technology Co., LTD |
-
- 1H-1-ethyl Candesartan Cilexetil
914613-35-7
- $37.00-119.00
- 98.19%
- TargetMol Chemicals Inc.
-
- Candesartan Cilexetil EP Impurity E
914613-35-7
- 0.98
- ShenZhen H&D Pharmaceutical Technology Co., LTD
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