2-Chloro-8-nitroquinoline
- CAS No.
- 4225-86-9
- Chemical Name:
- 2-Chloro-8-nitroquinoline
- Synonyms
- NSC 263744;MFCD00160589;2-Chloro-8-nitroquinoline;Quinoline, 2-chloro-8-nitro-
- CBNumber:
- CB42549765
- Molecular Formula:
- C9H5ClN2O2
- Molecular Weight:
- 208.6
- MDL Number:
- MFCD00160589
- MOL File:
- 4225-86-9.mol
- MSDS File:
- SDS
2-Chloro-8-nitroquinoline price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 126637 | 2-Chloro-8-nitroquinoline | 4225-86-9 | 1.00g | $1044 | 2026-05-18 | Buy |
| aablocks | AA00CIRA | 2-Chloro-8-nitroquinoline 95% | 4225-86-9 | 250mg | $26 | 2026-05-28 | Buy |
| aablocks | AA00CIRA | 2-Chloro-8-nitroquinoline 95% | 4225-86-9 | 1g | $36 | 2026-05-28 | Buy |
| aablocks | AA00CIRA | 2-Chloro-8-nitroquinoline 95% | 4225-86-9 | 5g | $177 | 2026-05-28 | Buy |
| aablocks | AA00CIRA | 2-Chloro-8-nitroquinoline 97% | 4225-86-9 | 10g | $320 | 2026-05-28 | Buy |
2-Chloro-8-nitroquinoline Chemical Properties, Uses, Production
Synthesis
612-62-4
4225-86-9
A mixed solution of nitric acid (16 mL) and sulfuric acid (8 mL) was slowly added dropwise to a solution of sulfuric acid (150 mL) containing 2-chloroquinoline (61.1 mmol) at 20 °C, keeping the reaction temperature at 0 °C. Subsequently, the reaction mixture was warmed up to 40 °C and maintained for 30 min. Upon completion of the reaction, the reaction was quenched with ice water (800 mL). The precipitated solid product was collected by filtration and purified by fast chromatography (eluent ratio of 20:1 petroleum ether/ethyl acetate) to finally obtain the target compound 2-chloro-8-nitroquinoline in 64% yield as a yellow solid.
References
[1] Patent: WO2009/23844, 2009, A2. Location in patent: Page/Page column 112
[2] Patent: WO2010/21797, 2010, A1. Location in patent: Page/Page column 75-76
[3] Patent: WO2010/24980, 2010, A1. Location in patent: Page/Page column 93; 94
[4] ChemMedChem, 2018,
[5] Australian Journal of Chemistry, 2003, vol. 56, # 1, p. 39 - 44
2-Chloro-8-nitroquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Chengdu Forest Science and Technology Development Co., Ltd. | 18030648795 18030648795 | sales@cdforestchem.com | China | 1998 | 58 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9509 | 58 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7854 | 55 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 8455 | 58 |
| parabiochem | 025-83453382-8005 | sale@parabiochem.com | China | 9577 | 55 |
| ChengDu TongChuangYuan Pharmaceutical Co.Ltd | 028-83379370 13880556291 | tcy@tcypharm.com | China | 8696 | 58 |
View Latest Price from 2-Chloro-8-nitroquinoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-13 | 2-Chloro-8-nitroquinoline
4225-86-9
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-07-06 | 2-Chloro-8-nitroquinoline
4225-86-9
|
$1.00 | 1kg | 98% | 200KG | Career Henan Chemical Co |
-
- 2-Chloro-8-nitroquinoline
4225-86-9
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 2-Chloro-8-nitroquinoline
4225-86-9
- $1.00
- 98%
- Career Henan Chemical Co
