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6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester

6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester structure

CAS No.: 1150566-27-0

Chemical Name:: 6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester

Synonyms: Ethyl 6-chloroiMidazo[1,2...;6-chloroimidazo[1,2-a]pyrazine-3-carboxylic acid;ethyl 6-chloroiMidazo[1,2-b]pyridazne-3-carboxylate;6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester;Imidazo[1,2-b]pyridazine-3-carboxylic acid, 6-chloro-, ethyl ester

CBNumber:: CB42574471

Molecular Formula:: C9H8ClN3O2

Molecular Weight:: 225.63

MDL Number:: MFCD11975600

MOL File:: 1150566-27-0.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:41

Product description	Number	Pack Size	Price
Ethyl6-Chloroimidazo[1,2-b]pyridazine-3-carboxylate	B124860	50mg	$45
Ethyl 6-chloroimidazo[1,2-b]pyridazine-3-carboxylate	OR927013	1g	$60
Ethyl 6-chloroimidazo[1,2-b]pyridazine-3-carboxylate	4H58-5-93	1g	$71
Ethyl 6-chloroimidazo[1,2-b]pyridazine-3-carboxylate	OR927013	5g	$173
Ethyl 6-chloroimidazo[1,2-b]pyridazine-3-carboxylate	4H58-5-93	5G	$205
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6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester Properties

Density	1.47±0.1 g/cm3(Predicted)
storage temp.	2-8°C
pka	0.88±0.30(Predicted)
Appearance	White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319
Precautionary statements	P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
HS Code	2928009090

6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester price More Price(13)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	B124860	Ethyl6-Chloroimidazo[1,2-b]pyridazine-3-carboxylate	1150566-27-0	50mg	$45	2021-12-16	Buy
Apolloscientific	OR927013	Ethyl 6-chloroimidazo[1,2-b]pyridazine-3-carboxylate	1150566-27-0	1g	$60	2021-12-16	Buy
SynQuest Laboratories	4H58-5-93	Ethyl 6-chloroimidazo[1,2-b]pyridazine-3-carboxylate	1150566-27-0	1g	$71	2021-12-16	Buy
Apolloscientific	OR927013	Ethyl 6-chloroimidazo[1,2-b]pyridazine-3-carboxylate	1150566-27-0	5g	$173	2021-12-16	Buy
SynQuest Laboratories	4H58-5-93	Ethyl 6-chloroimidazo[1,2-b]pyridazine-3-carboxylate	1150566-27-0	5G	$205	2021-12-16	Buy

Product number	Packaging	Price	Buy
B124860	50mg	$45	Buy
OR927013	1g	$60	Buy
4H58-5-93	1g	$71	Buy
OR927013	5g	$173	Buy
4H58-5-93	5G	$205	Buy

6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester Chemical Properties,Uses,Production

Uses

6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester is mainly used as pharmaceutical intermediates.

Synthesis

Pyridazinium, 3-chloro-6-[[(dimethylamino)methylene]amino]-1-(2-ethoxy-2-oxoethyl)-, bromide (1:1)

1150566-26-9

6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester

1150566-27-0

General procedure for the synthesis of ethyl 6-chloroimidazo[1,2-B]pyridazine-3-carboxylate from the compound (CAS:1150566-26-9): S-chloro-β-dimethylamino-methyleneamino-J-isoethyloxycarbonylmethyl-pyridazine-1-bromide (11.40 g, 32.40 mmol) was dissolved in acetonitrile (200 mL), followed by addition of diisopropylethylamine (15.22 mL, 64.81 mmol). The reaction mixture was stirred at room temperature for 4 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure and the residue was ground with water to afford 5.77 g of ethyl 6-chloroimidazo[1,2-b]pyridazine-3-carboxylate as a light brown solid in 77% yield. The product was characterized by 1H NMR (300 MHz, CDCl3): δ 8.36 (1H, s), 8.01 (1H, d, J = 9.4 Hz), 7.27 (1H, d, J = 9.4 Hz), 4.46 (2H, q, J = 7.1 Hz), 1.37 (3H, t, J = 7.1 Hz).LCMS analysis showed m/z 226 [M + 1]+ (molecular weight: 225.64).

References

[1] Patent: WO2009/60197, 2009, A1. Location in patent: Page/Page column 59
[2] Patent: US2012/65184, 2012, A1. Location in patent: Page/Page column 37

6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester synthesis

Synthesis of 6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester from Pyridazinium, 3-chloro-6-[[(dimethylamino)methylene]amino]-1-(2-ethoxy-2-oxoethyl)-, bromide (1:1)

6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester Preparation Products And Raw materials

Raw materials

Pyridazinium, 3-chloro-6-[[(dimethylamino)methylene]amino]-1-(2-ethoxy-2-oxoethyl)-, bromide (1:1) 6-Chloropyridazin-3-amine ETHYL TRANS-3-ETHOXYACRYLATE, 98 2-Chloro-3-oxopropionic acid ethyl ester N,N-Diisopropylethylamine

Acetonitrile

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Preparation Products

6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester Suppliers

Global( 109)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Speranza Chemical Co., Ltd.	+86-86-075521030354 +8618688942810	sophieliu@speranzachem.com	China	923	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29821	58
Win-Win Chemical CO., Limited	0086-577-64498589	sales@win-winchemical.com	CHINA	998	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Shanghai Rlavie Technology Co ltd	+86-021-67759270 +8617717059219	sales@rlavie.com	China	1030	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14304	58
Blocksynth Pharmaceutical Technology Co.,Ltd	0086-19817745290; +8619817745290	bd@blocksynth.com	China	5973	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19987	58

Supplier	Advantage
Speranza Chemical Co., Ltd.	55
career henan chemical co	58
Win-Win Chemical CO., Limited	58
Alchem Pharmtech,Inc.	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Shanghai Rlavie Technology Co ltd	58
Win-Win chemical CO., Limited	58
Blocksynth Pharmaceutical Technology Co.,Ltd	58
Hefei Hirisun Pharmatech Co., Ltd	58
Labnetwork lnc.	58

View Lastest Price from 6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2022-01-04	ethyl 6-chloroimidazo[1,2-b]pyridazine-3-carboxylate 1150566-27-0	US $0.00-0.00 / KG	1g	98%minHPLC	50kgs/month	Shanghai Rlavie Technology Co ltd
	2019-07-06	6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester 1150566-27-0	US $1.00 / KG	1KG	98%	150KG	Career Henan Chemical Co

ethyl 6-chloroimidazo[1,2-b]pyridazine-3-carboxylate
1150566-27-0
US $0.00-0.00 / KG
98%minHPLC
Shanghai Rlavie Technology Co ltd

6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester
1150566-27-0
US $1.00 / KG
98%
Career Henan Chemical Co

6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester Spectrum

6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester(1150566-27-0)¹HNMR

1150566-27-0(6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester)Related Search:

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6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester Ethyl 6-chloroiMidazo[1,2... ethyl 6-chloroiMidazo[1,2-b]pyridazne-3-carboxylate 6-chloroimidazo[1,2-a]pyrazine-3-carboxylic acid Imidazo[1,2-b]pyridazine-3-carboxylic acid, 6-chloro-, ethyl ester 1150566-27-0