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ChemicalBook >> CAS DataBase List >>3,6-Dichloroimidazo[1,2-b]pyridazine

3,6-Dichloroimidazo[1,2-b]pyridazine

3,6-Dichloroimidazo[1,2-b]pyridazine Structure
3,6-Dichloroimidazo[1,2-b]pyridazine structure
CAS No.
40972-42-7
Chemical Name:
3,6-Dichloroimidazo[1,2-b]pyridazine
Synonyms
3,6-Dichloroimidazo[1,2-b]pyridazine;Imidazo[1,2-b]pyridazine, 3,6-dichloro-
CBNumber:
CB02471190
Molecular Formula:
C6H3Cl2N3
Molecular Weight:
188.01
MDL Number:
MFCD11520887
MOL File:
40972-42-7.mol
MSDS File:
SDS
Last updated:2026-05-27 17:24:41
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3,6-Dichloroimidazo[1,2-b]pyridazine Properties

Density 1.69±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 0.88±0.30(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

3,6-Dichloroimidazo[1,2-b]pyridazine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 114779 3,6-Dichloroimidazo[1,2-b]pyridazine 40972-42-7 1.00g $122 2026-05-18 Buy
Matrix Scientific 114779 3,6-Dichloroimidazo[1,2-b]pyridazine 40972-42-7 5.00g $361 2026-05-18 Buy
Matrix Scientific 114779 3,6-Dichloroimidazo[1,2-b]pyridazine 40972-42-7 10.00g $587 2026-05-18 Buy
aablocks AA00CLA3 3,6-Dichloroimidazo[1,2-b]pyridazine 98% 40972-42-7 250mg $23 2026-05-28 Buy
aablocks AA00CLA3 3,6-Dichloroimidazo[1,2-b]pyridazine 98% 40972-42-7 1g $68 2026-05-28 Buy
Product number Packaging Price Buy
114779 1.00g $122 Buy
114779 5.00g $361 Buy
114779 10.00g $587 Buy
AA00CLA3 250mg $23 Buy
AA00CLA3 1g $68 Buy

3,6-Dichloroimidazo[1,2-b]pyridazine Chemical Properties, Uses, Production

Synthesis

6-Chloroimidazo[2,1-f]pyridazine

6775-78-6

3,6-Dichloroimidazo[1,2-b]pyridazine

40972-42-7

6-Chloroimidazo[1,2-b]pyridazine (6.53 mmol) was used as starting material, which was dissolved in chloroform (12 mL) and N-chlorosuccinimide (6.53 mmol) was added under nitrogen protection. The reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the mixture was partitioned between saturated sodium bisulfate solution (25 mL) and chloroform (12 mL). The organic layer was separated, washed with water (2 x 12 mL), dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford 3,6-dichloroimidazo[1,2-b]pyridazine (1.05 g, 85% yield) as an orange solid. The structure of the product was confirmed by 1H NMR (500 MHz, CDCl3): δ 7.92 (d, J = 9.5 Hz, 1H), 7.74 (s, 1H), 7.12 (d, J = 9.5 Hz, 1H). 3,6-Dichloroimidazo[1,2-b]pyridazine (150 mg, 0.8 mmol) was placed in a sealed tube with the corresponding amine (1 mL) and heated at 120 °C for 16 hours. At the end of the reaction, it was cooled to room temperature and the reaction mixture was concentrated under reduced pressure. Purification by column chromatography (using a 12 g ISCO column with the eluent being a solvent mixture of dichloromethane and ammonia-containing methanol (10:1) at a flow rate of 25 mL/min with a gradient elution from 100% dichloromethane to 80% dichloromethane over a period of 30 min) yielded the target product 6.

References

[1] Patent: US2008/153813, 2008, A1. Location in patent: Page/Page column 5

3,6-Dichloroimidazo[1,2-b]pyridazine Preparation Products And Raw materials

Raw materials

6-Chloroimidazo[2,1-f]pyridazine Chloroform N-Chlorosuccinimide

Preparation Products

3,6-Dichloroimidazo[1,2-b]pyridazine Suppliers

Global Suppliers ( 58)
Supplier Tel Email Country ProdList Advantage
Chiba Pharmaceutical Science and technology Co, Ltd. 0531-81313138 13066006660 chibapharm@foxmail.com China 3995 55
Shanghai Litong Chemical Technology Co.,Ltd. 13598610367 0373-7129549 2468833170@qq.com China 932 58
SuZhou ShiYa Biopharmaceuticals, Inc. 86(512)5235 8471 17715136450 sales@shiyabiopharm.com China 4167 58
SynAsst Chemical. 021-60343070 China 12731 55
Shanghai Hekang Biotechnology Co., Ltd. 17721021104 18939837085 2880152141@qq.com China 1840 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Worldyang Chemical Co.,Ltd. 021-56795766 sales@worldyachem.com China 9475 58
NovoChemy Ltd. 86-(0)21-31261262 373522135 sales@novochemy.com China 6491 58
Shanghai RenYue Chemical Technology Co., Ltd. 021-62219190; 18321139117 316441092@qq.com China 3000 55
Shangdong Youbang Biochemical Technology Co.,LTD. 15098208899 3368029756@qq.com China 292 58
Supplier Advantage
Chiba Pharmaceutical Science and technology Co, Ltd. 55
Shanghai Litong Chemical Technology Co.,Ltd. 58
SuZhou ShiYa Biopharmaceuticals, Inc. 58
SynAsst Chemical. 55
Shanghai Hekang Biotechnology Co., Ltd. 55
Bide Pharmatech Ltd. 60
Shanghai Worldyang Chemical Co.,Ltd. 58
NovoChemy Ltd. 58
Shanghai RenYue Chemical Technology Co., Ltd. 55
Shangdong Youbang Biochemical Technology Co.,LTD. 58

View Latest Price from 3,6-Dichloroimidazo[1,2-b]pyridazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,6-Dichloroimidazo[1,2-b]pyridazine pictures 2022-01-04 3,6-Dichloroimidazo[1,2-b]pyridazine
40972-42-7
 1g 98%minHPLC 50kgs/month Shanghai Rlavie Technology Co ltd
3,6-Dichloroimidazo[1,2-b]pyridazine pictures 2019-12-26 3,6-Dichloroimidazo[1,2-b]pyridazine
40972-42-7
 $6.60 1KG 97%-99% 1kg-1000kg Career Henan Chemical Co

3,6-Dichloroimidazo[1,2-b]pyridazine Spectrum

3,6-Dichloroimidazo[1,2-b]pyridazine(40972-42-7)1HNMR

40972-42-7 (3,6-Dichloroimidazo[1,2-b]pyridazine) Related Search:

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IMidazo[1,2-b]pyridazine-3-carboxylic acid 6-Chloro-iMidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester 2-Pyridinecarboxylic acid, 3,6-dichloro-, ethyl ester Ethyl 3,6-dibromopicolinate 3,6-dichloropyridazine-4-carboxaMide
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3,6-Dichloroimidazo[1,2-b]pyridazine Imidazo[1,2-b]pyridazine, 3,6-dichloro- 40972-42-7