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ChemicalBook >> CAS DataBase List >>4-Amino-2,3,5,6-tetrafluoropyridine

4-Amino-2,3,5,6-tetrafluoropyridine

4-Amino-2,3,5,6-tetrafluoropyridine Structure
4-Amino-2,3,5,6-tetrafluoropyridine structure
CAS No.
1682-20-8
Chemical Name:
4-Amino-2,3,5,6-tetrafluoropyridine
Synonyms
4-AMINOTETRAFLUOROPYRIDINE;4-AMino-2,3,5,6-terafluoropyridine;2,3,5,6-tetrafluoro-4-pyridinamine;4-Amino-2,3,5,6-tetrafluoropyridine;4-Pyridinamine, 2,3,5,6-tetrafluoro-;4-AMINO-2,3,5,6-TETRAFLUORROPYRIDINE;2,3,5,6-Tetrafluoro-pyridin-4-ylamine;4-Amino-2,3,5,6-tetrafluoropyridine >4-Amino-2,3,5,6-tetrafluoropyridine 98%;4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE ISO 9001：2015 REACH
CBNumber:
CB4269375
Molecular Formula:
C5H2F4N2
Molecular Weight:
166.08
MDL Number:
MFCD00010855
MOL File:
1682-20-8.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:43
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4-Amino-2,3,5,6-tetrafluoropyridine Properties

Melting point 85-87 °C (lit.)
Boiling point 85-86 °C
Density 1.631±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form powder to crystal
pka -3.11±0.10(Predicted)
color White to Light yellow to Light orange
BRN 475870
InChI InChI=1S/C5H2F4N2/c6-1-3(10)2(7)5(9)11-4(1)8/h(H2,10,11)
InChIKey PLVFNMQHMRRBAA-UHFFFAOYSA-N
SMILES C1(F)=NC(F)=C(F)C(N)=C1F
CAS DataBase Reference 1682-20-8(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-36/37/38
Safety Statements  26-36
WGK Germany  3
Hazard Note  Irritant
HS Code  29333990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
2 0

4-Amino-2,3,5,6-tetrafluoropyridine price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 300624 4-Amino-2,3,5,6-tetrafluoropyridine 98% 1682-20-8 1g $33.8 2026-04-30 Buy
TCI Chemical A1546 4-Amino-2,3,5,6-tetrafluoropyridine >97.0%(GC) 1682-20-8 1g $29 2026-04-30 Buy
Apolloscientific PC5620 4-Aminotetrafluoropyridine 98% 1682-20-8 1g $21 2026-06-04 Buy
Apolloscientific PC5620 4-Aminotetrafluoropyridine 98% 1682-20-8 5g $25 2026-06-04 Buy
Apolloscientific PC5620 4-Aminotetrafluoropyridine 98% 1682-20-8 10g $44 2026-06-04 Buy
Product number Packaging Price Buy
300624 1g $33.8 Buy
A1546 1g $29 Buy
PC5620 1g $21 Buy
PC5620 5g $25 Buy
PC5620 10g $44 Buy

4-Amino-2,3,5,6-tetrafluoropyridine Chemical Properties, Uses, Production

Synthesis

In principle, ammonia could be used to allow indirect replacement of fluorine by hydrogen. Workers in this laboratory showed that pentafluoropyridine reacted with ammonia giving 4-aminotetrafluoropyridine.
synthesis of 4-aminotetrafluoropyridine

Chemical Properties

white to light yellow crystal

Uses

4-Amino-2,3,5,6-tetrafluoropyridine is formed as C-H ′insertion′ product during reaction with 4-azido-2,3,5,6-tetrafluoropyridine.

General Description

4-Amino-2,3,5,6-tetrafluoropyridine is formed as C-H ′insertion′ product during reaction with 4-azido-2,3,5,6-tetrafluoropyridine.

References

[1] Journal of Fluorine Chemistry, 1996, vol. 81, # 1, p. 39 - 42
[2] Journal of the American Chemical Society, 2017, vol. 139, # 37, p. 13092 - 13101
[3] Oriental Journal of Chemistry, 2016, vol. 32, # 4, p. 1799 - 1813
[4] Journal of Organic Chemistry USSR (English Translation), 1988, vol. 24, # 12, p. 2267 - 2272
[5] Zhurnal Organicheskoi Khimii, 1988, vol. 24, # 12, p. 2513 - 2518

4-Amino-2,3,5,6-tetrafluoropyridine Preparation Products And Raw materials

Raw materials

Pentafluoropyridine Tetrahydrofuran Ammonium hydroxide

Preparation Products

2,3,5,6-Tetrafluoro-4-nitropyridine 4-Bromo-2,3,5,6-tetrafluoropyridine

4-Amino-2,3,5,6-tetrafluoropyridine Suppliers

Global Suppliers ( 133)
Supplier Tel Email Country ProdList Advantage
Nanjing Lynsci Chemical Co., Ltd +86-025-83208253 +86-13851694729 layefe@163.com China 234 62
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Supplier Advantage
Nanjing Lynsci Chemical Co., Ltd 62
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Pure Chemistry Scientific Inc. 62

View Latest Price from 4-Amino-2,3,5,6-tetrafluoropyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE pictures 2025-06-25 4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE
1682-20-8
 $1.10 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE pictures 2025-04-04 4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE
1682-20-8
 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE pictures 2020-01-13 4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE
1682-20-8
 $1.00 1KG 98%-99.9% 200kg Career Henan Chemical Co

4-Amino-2,3,5,6-tetrafluoropyridine Spectrum

4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE(1682-20-8)1HNMR4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE(1682-20-8)Raman4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE(1682-20-8)IR

1682-20-8 (4-Amino-2,3,5,6-tetrafluoropyridine) Related Search:

2,3,4,5,6-Pentafluoroaniline 4-Amino-3,5-dichloro-2,6-difluoropyridine 4-Amino-2,3,5,6-tetrafluoropyridine 2,3,5,6-Tetrafluoropyridine 4-(Dimethylamino)-2,3,5,6-tetrafluoropyridine
2,3,5,6-Tetrafluoro-4-nitropyridine 2,3,5,6-Tetrafluoro-4-hydrazinopyridine N-[2-Chloro-5-(trifluoromethyl)phenyl]-4-(2,3,5,6-tetrafluoropyridin-4-yl)piperazine-1-carboxamide 2-(2,3,5,6-Tetrafluoropyridin-4-yl)-N-[3-(trifluoromethyl)phenyl]hydrazinecarboxamide N-[(3,4-Dichlorophenyl)sulfonyl]-4-(2,3,5,6-tetrafluoropyridin-4-yl)piperazine-1-carboxamide
N-[(4-Fluorophenyl)sulfonyl]-4-(2,3,5,6-tetrafluoropyridin-4-yl)piperazine-1-carboxamide 2-(2,3,5,6-Tetrafluoropyridin-4-yl)-N-[2-(trifluoromethyl)phenyl]hydrazinecarboxamide 2-(2,3,5,6-Tetrafluoropyridin-4-yl)-N-[4-(trifluoromethyl)phenyl]hydrazinecarboxamide 4-(2,3,5,6-Tetrafluoropyridin-4-yl)-N-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazine-1-carboxamide 2-(2,3,5,6-Tetrafluoropyridin-4-yl)-N-[4-(trifluoromethoxy)phenyl]hydrazinecarbothioamide
N-{[2-Chloro-5-(trifluoromethyl)phenyl]sulfonyl}-4-(2,3,5,6-tetrafluoropyridin-4-yl)piperazine-1-carboxamide N-[(3,5-Dichlorophenyl)sulfonyl]-4-(2,3,5,6-tetrafluoropyridin-4-yl)piperazine-1-carboxamide 4-(2,3,5,6-Tetrafluoropyridin-4-yl)-N-{[2-(trifluoromethyl)phenyl]sulfonyl}piperazine-1-carboxamide

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4-AMINO-2,3,5,6-TETRAFLUORROPYRIDINE 4-AMINOTETRAFLUOROPYRIDINE 2,3,5,6-Tetrafluoro-pyridin-4-ylamine 4-AMino-2,3,5,6-terafluoropyridine 4-Amino-2,3,5,6-tetrafluoropyridine 98% 4-Pyridinamine, 2,3,5,6-tetrafluoro- 2,3,5,6-tetrafluoro-4-pyridinamine 4-Amino-2,3,5,6-tetrafluoropyridine > 4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE ISO 9001：2015 REACH 4-Amino-2,3,5,6-tetrafluoropyridine 1682-20-8 C5H2F4N2 AMINE Halopyridines Fluoropyridines Building Blocks C5 Heterocyclic Building Blocks Pyridines Fluoropyridines Halopyridines C5 Heterocyclic Building Blocks Pyridines Pyridine Heterocyclic Compounds Building Blocks Chemical Synthesis Fluorinated Building Blocks Heterocyclic Building Blocks Heterocyclic Fluorinated Building Blocks Other Fluorinated Heterocycles