ChemicalBook >> CAS DataBase List >>ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE
ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE
- CAS No.
- 26893-12-9
- Chemical Name:
- ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE
- Synonyms
- BUTTPARK 10\01-32;ethyl 4-oxo-6-(trifluoromethyl)-1H-quinoline-3-carboxylate;ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE;ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)-3-QUINOLINECARBOXYLATE;4-HYDROXY-6-TRIFLUOROMETHYLQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER;4-oxo-6-(trifluoromethyl)-1H-quinoline-3-carboxylic acid ethyl ester;3-Quinolinecarboxylic acid, 4-hydroxy-6-(trifluoromethyl)-, ethyl ester;3-(Ethoxycarbonyl)-6-(trifluoromethyl)quinolin-4-ol, 3-(Ethoxycarbonyl)-4-hydroxy-6-(trifluoromethyl)quinoline
- CBNumber:
- CB4279909
- Molecular Formula:
- C13H10F3NO3
- Molecular Weight:
- 285.22
- MDL Number:
- MFCD00173369
- MOL File:
- 26893-12-9.mol
- MSDS File:
- SDS
Last updated:2026-05-28 05:43:28
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P301+P312-P261 |
| Hazard Codes | Xi |
| Hazard Note | Irritant |
| HS Code | 2933499090 |
ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 007022 | Ethyl 4-hydroxy-6-(trifluoromethyl)-3-quinolinecarboxylate | 26893-12-9 | 1.00g | $49 | 2026-05-18 | Buy |
| Matrix Scientific | 007022 | Ethyl 4-hydroxy-6-(trifluoromethyl)-3-quinolinecarboxylate | 26893-12-9 | 5.00g | $135 | 2026-05-18 | Buy |
| Heterocyclics | JR-13083 | Ethyl 6-(trifluoromethyl)-4-hydroxyquinoline-3-carboxylate 95% | 26893-12-9 | 5g | $120 | 2026-06-05 | Buy |
| Heterocyclics | JR-13083 | Ethyl 6-(trifluoromethyl)-4-hydroxyquinoline-3-carboxylate 95% | 26893-12-9 | 25g | $415 | 2026-06-05 | Buy |
| aablocks | AA003Q84 | ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE 96% | 26893-12-9 | 1g | $24 | 2026-05-28 | Buy |
ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE Chemical Properties,Uses,Production
Synthesis
49713-39-5
26893-12-9
GENERAL METHODS: Polyphosphoric acid (PPA) (2 eq. by weight) was mixed with Intermediate 1 (40 mmol), followed by the addition of phosphoryl chloride (POCl3) (10 mmol). The reaction mixture was heated to 75 °C and maintained for 8 h. The reaction progress was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the mixture was quenched by slowly pouring it into 10% sodium hydroxide solution in an ice bath while adjusting the pH to about 7. The resulting solid was separated by filtration, dried, and washed with ether (3 x 20 mL) to afford ethyl 4-hydroxy-6-trifluoromethylquinoline-3-carboxylate in good yield.
References
[1] European Journal of Medicinal Chemistry, 2015, vol. 103, p. 1 - 16
[2] Organic Process Research and Development, 2014, vol. 18, # 11, p. 1482 - 1491
[3] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 6, p. 1577 - 1580
Synthesis of ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE from (4-TRIFLUOROMETHYLPHENYLAMINO)METHYLENEMALONIC ACID DIETHYL ESTER
ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE Preparation Products And Raw materials
Raw materials
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Preparation Products
Global( 70)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3996 | 55 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| SuZhou ShiYa Biopharmaceuticals, Inc. | 86(512)5235 8471 17715136450 | sales@shiyabiopharm.com | China | 4167 | 58 |
| Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. | +86-28-85122536 85324413 | market@astatech.cn | China | 8016 | 55 |
| Shanghai Run-Biotech Co., Ltd. | 021-57171705 13817537615 | sales@run-biotech.com | China | 2283 | 58 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 8455 | 58 |
| Nanjing ERan Biological Pharmaceutical Co., Ltd. | 13770809694 | googlexu_0114@sina.com | China | 992 | 58 |
| Accela ChemBio Inc. | +1(858) 699-3322 | marketing@accelachem.com | United States | 6022 | 65 |
View Lastest Price from ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE
26893-12-9
|
$2.00 | 1KG | 99% | Career Henan Chemical Co |
-
- ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE
26893-12-9
- $2.00
- 99%
- Career Henan Chemical Co
26893-12-9(ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE)Related Search:
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ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE
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BUTTPARK 10\01-32
ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)-3-QUINOLINECARBOXYLATE
ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE
4-HYDROXY-6-TRIFLUOROMETHYLQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
3-(Ethoxycarbonyl)-6-(trifluoromethyl)quinolin-4-ol, 3-(Ethoxycarbonyl)-4-hydroxy-6-(trifluoromethyl)quinoline
4-oxo-6-(trifluoromethyl)-1H-quinoline-3-carboxylic acid ethyl ester
ethyl 4-oxo-6-(trifluoromethyl)-1H-quinoline-3-carboxylate
3-Quinolinecarboxylic acid, 4-hydroxy-6-(trifluoromethyl)-, ethyl ester
26893-12-9
Acids and Derivatives
Heterocycles
