Angiogenesis Inhibitor
- CAS No.
- 186611-44-9
- Chemical Name:
- Angiogenesis Inhibitor
- Synonyms
- Angiogenesis Inhibitor;Angiogenesis Inhibitor - CAS 186611-44-9 - Calbiochem;2H-Indol-2-one, 1,3-dihydro-3-(1H-imidazol-5-ylmethylene)-
- CBNumber:
- CB43136740
- Molecular Formula:
- C12H9N3O
- Molecular Weight:
- 211.22
- MDL Number:
- MOL File:
- 186611-44-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 228-230 °C(Solv: ethanol (64-17-5)) |
|---|---|
| Boiling point | 572.7±50.0 °C(Predicted) |
| Density | 1.404±0.06 g/cm3(Predicted) |
| storage temp. | +2C to +8C |
| solubility | DMSO: 5mg/mL |
| form | Yellow solid |
| pka | 11.70±0.20(Predicted) |
| color | yellow |
| NCI Dictionary of Cancer Terms | angiogenesis inhibitor |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
Angiogenesis Inhibitor price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 175580 | Angiogenesis Inhibitor - CAS 186611-44-9 - Calbiochem | 186611-44-9 | 10mg | $190 | 2026-04-30 | Buy |
| TRC | A637973 | AngiogenesisInhibitor | 186611-44-9 | 10mg | $170 | 2021-12-16 | Buy |
| TRC | A637973 | AngiogenesisInhibitor | 186611-44-9 | 25mg | $335 | 2021-12-16 | Buy |
Angiogenesis Inhibitor Chemical Properties,Uses,Production
Uses
Angiogenesis Inhibitor is a cell-permeable indolinone. Anti-angiogenic activity.
Definition
ChEBI: 3-(1H-imidazol-5-ylmethylidene)-1H-indol-2-one is a member of indoles.
General Description
A cell-permeable indolinone compound that displays anti-angiogenesis properties (30% inhibition of control at 10 μM in an in vitro rat aortic ring model). The potency has been reported to be comparable to that of SU5416 (Cat. No. 676487; 22% inhibition of control at 10 μM). Acts as a moderate ATP-competitive inhibitor of hEGF-R tyrosine kinase activity (54% inhibition at 10 μM).
Biochem/physiol Actions
Cell permeable: yes
Angiogenesis Inhibitor Preparation Products And Raw materials
Raw materials
Preparation Products
Angiogenesis Inhibitor Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
| Shaoguan Qicheng Biotechnology Co., Ltd | 18122215013 | 780229652@qq.com | China | 1392 | 58 |
| TargetMol | 400-821-0310 15002144251 | xuexiang.shao@tsbiochem.com | China | 29128 | 58 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
| Energy Chemical | 58 |
| Shaoguan Qicheng Biotechnology Co., Ltd | 58 |
| TargetMol | 58 |
