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EBELACTONE A

CAS No.
76808-16-7
Chemical Name:
EBELACTONE A
Synonyms
Nsc 335650;Ebelactone;EBELACTONE A;ebelactone a microbial;Ebelactone A microbial esterase inhibitor;4-beta(1r*,3e,5s*,7r*,8s*,9s*)))-3s-(3-alph;3,11-DIHYDROXY-2,4,6,8,10,12-HEXAMETHYL-9-OXO-6-TETRADECEN-3-OLIDE;3,11-DIHYDROXY-2,4,6,8,10,12-HEXAMETHYL-9-OXO-6-TETRADECENOIC 1,3-LACTONE;3,11-DIHYDROXY-2,4,6,8,10,12-HEXAMETHYL-9-OXO-6-TETRADECANOIC-1,3-LACTONE;3,11-DIHYDROXY-2,4,5,6,10,12-HEXAMETHYL-9-OXO-6-TETRADECENOIC 1,3-LACTONE
CBNumber:
CB4319218
Molecular Formula:
C20H34O4
Molecular Weight:
338.48
MDL Number:
MFCD00036710
MOL File:
76808-16-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:22

EBELACTONE A Properties

storage temp. 2-8°C
solubility DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 25 mg/ml; Ethanol: 20 mg/ml
form White crystalline powder.
biological source Streptomyces sp.
UNSPSC Code 12352202
NACRES NA.77

SAFETY

Risk and Safety Statements

WGK Germany  3
RTECS  RQ7730000

EBELACTONE A price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E0761 Ebelactone A microbial esterase inhibitor 76808-16-7 1mg $429 2026-04-30 Buy
Cayman Chemical 19163 Ebelactone A ≥98% 76808-16-7 500μg $69 2026-04-30 Buy
Cayman Chemical 19163 Ebelactone A ≥98% 76808-16-7 1mg $106 2026-04-30 Buy
Biosynth IEB-4155 Ebelactone A 76808-16-7 25mg $4062.25 2026-06-04 Buy
ChemScene CS-0105313 Ebelactone A 76808-16-7 500??g $147 2026-06-04 Buy
Product number Packaging Price Buy
E0761 1mg $429 Buy
19163 500μg $69 Buy
19163 1mg $106 Buy
IEB-4155 25mg $4062.25 Buy
CS-0105313 500??g $147 Buy

EBELACTONE A Chemical Properties, Uses, Production

Description

Ebelactone A is a β-lactone enzyme inhibitor that was first isolated from a cultured strain of soil actinomycetes. It can inhibit esterases, lipases, and N-formylmethionine aminopeptidases (IC50s = 0.056, 0.003, and 0.08 μg/ml, respectively) found on cell surfaces, which has been shown to stimulate host defense in immune cells. Ebelactone A is also reported to inhibit cutinases produced by fungal pathogens, thus demonstrating a plant-protective function.

Uses

Ebelactone A is a mycolic acid β-lactone, which exhibits inhibitory activity for esterase, lipase, fMet aminopeptidase (fMet AP) and PNBase, with IC50s of 56, 3, 8 and 7.5 μM, respectively[1]. Ebelactone A inhibits cutinase, exhibits plants protective potency against Erysiphe graminis[2].

References

[1] Umezawa H, et al., Ebelactone, an inhibitor of esterase, produced by actinomycetes. J Antibiot (Tokyo). 1980 Dec;33(12):1594-6. DOI:10.7164/antibiotics.33.1594
[2] Francis S A, et al., The role of cutinase in germling development and infection byErysiphe graminisf. sp. hordei[J]. Physiological and Molecular Plant Pathology, 1996, 49(3): 201-211.

EBELACTONE A Preparation Products And Raw materials

Raw materials

Preparation Products

EBELACTONE A Suppliers

Global Suppliers ( 36)
Supplier Tel Email Country ProdList Advantage
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4773 55
BOC Sciences 16314854226 info@bocsci.com United States 9909 65
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Zhejiang Huida Biotech Co., LTD 0571-89903022 18679456698 zilong@hizyme.com China 8001 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58

View Latest Price from EBELACTONE A manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ebelactone A pictures 2025-12-22 Ebelactone A
76808-16-7
10g TargetMol Chemicals Inc.
4-(8-hydroxy-1,3,5,7,9-pentamethyl-6-oxo-3-undecenyl)-3-methyl-2-oxetanon( 4-beta(1r*,3e,5s*,7r*,8s*,9s*)))-3s-(3-alph EBELACTONE A 3,11-DIHYDROXY-2,4,5,6,10,12-HEXAMETHYL-9-OXO-6-TETRADECENOIC 1,3-LACTONE 3,11-DIHYDROXY-2,4,6,8,10,12-HEXAMETHYL-9-OXO-6-TETRADECANOIC-1,3-LACTONE 3,11-DIHYDROXY-2,4,6,8,10,12-HEXAMETHYL-9-OXO-6-TETRADECEN-3-OLIDE 3,11-DIHYDROXY-2,4,6,8,10,12-HEXAMETHYL-9-OXO-6-TETRADECENOIC 1,3-LACTONE 3,11-DIHYDROXY-2,4,6,8,10,12-HEXAMETHYL-9-OXO-6-TETRADECENOIC ACID 1,3-LACTONE ebelactone a microbial (3S)-4α-[(1S,3E,5R,7S,8R,9R)-8-Hydroxy-1,3,5,7,9-pentamethyl-6-oxo-3-undecenyl]-3β-methyloxetan-2-one 2-Oxetanone, 4-(8-hydroxy-1,3,5,7,9-pentamethyl-6-oxo-3-undecenyl)-3-methyl-, (3S-(3-alpha,4-beta(1R*,3E,5S*,7R*,8S*,9S*)))- Nsc 335650 2-Oxetanone, 4-[(1S,3E,5R,7S,8R,9R)-8-hydroxy-1,3,5,7,9-pentamethyl-6-oxo-3-undecen-1-yl]-3-methyl-, (3S,4S)- Ebelactone A microbial esterase inhibitor Ebelactone 76808-16-7 BioChemical Biochemicals and Reagents Esterase, lipase and N-formylmethionine aminopeptidase Enzyme Inhibitors D to K Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Enzyme