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6-Methoxy-2-tetralone

6-Methoxy-2-tetralone Structure
6-Methoxy-2-tetralone structure
CAS No.
2472-22-2
Chemical Name:
6-Methoxy-2-tetralone
Synonyms
6-Methoxytetralin-2-one;6-METHOXY-3,4-DIHYDRONAPHTHALEN-2(1H)-ONE;Compound Fr12288;6-methoxy-2-Tetrlone;4-dihydro-6-Methoxy-;6-METHOXY-2-TETRALONE;6-methoxyl-2-tetralone;6-Methoxy-2-tetralone>6-METHOXY-2-TETRALONE 95%;6-Methoxy-2-tetralone,98%
CBNumber:
CB4323880
Molecular Formula:
C11H12O2
Molecular Weight:
176.21
MDL Number:
MFCD00001729
MOL File:
2472-22-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:58:37
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6-Methoxy-2-tetralone Properties

Melting point 28-35 °C
Boiling point 114-116 °C (0.2 mmHg)
Density 1.0431 (rough estimate)
refractive index n20/D 1.5645(lit.)
Flash point >230 °F
storage temp. 2-8°C
form Crystalline Low Melting Solid
color Light yellow-beige to orange
Sensitive Air Sensitive
BRN 513418
InChI InChI=1S/C11H12O2/c1-13-11-5-3-8-6-10(12)4-2-9(8)7-11/h3,5,7H,2,4,6H2,1H3
InChIKey RMRKDYNVZWKAFP-UHFFFAOYSA-N
SMILES C1C2=C(C=C(OC)C=C2)CCC1=O
CAS DataBase Reference 2472-22-2(CAS DataBase Reference)
FDA UNII LAV9W5N9D9
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P233-P260-P261-P264-P271-P280-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501
PPE Eyeshields, Gloves
Hazard Codes  Xi
Safety Statements  24/25
WGK Germany  3
HazardClass  IRRITANT
HS Code  29145090
Storage Class 10 - Combustible liquids
NFPA 704
1
2 0

6-Methoxy-2-tetralone price More Price(58)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 184063 6-Methoxy-3,4-dihydro-2(1H)-naphthalenone 95% 2472-22-2 1g $66.2 2024-03-01 Buy
Sigma-Aldrich 184063 6-Methoxy-3,4-dihydro-2(1H)-naphthalenone 95% 2472-22-2 5g $314 2024-03-01 Buy
TCI Chemical M1317 6-Methoxy-2-tetralone >95.0%(GC) 2472-22-2 1g $87 2026-04-30 Buy
TCI Chemical M1317 6-Methoxy-2-tetralone >95.0%(GC) 2472-22-2 5g $395 2021-12-16 Buy
Usbiological 283922 6-Methoxy-2-tetralone Asreported 2472-22-2 500mg $333 2026-06-03 Buy
Product number Packaging Price Buy
184063 1g $66.2 Buy
184063 5g $314 Buy
M1317 1g $87 Buy
M1317 5g $395 Buy
283922 500mg $333 Buy

6-Methoxy-2-tetralone Chemical Properties, Uses, Production

Description

6-methoxy-2-tetralone has been selected as the starting material for the synthesis of many steroidal compounds, including 2-aminotetalin derivatives, which exhibit antifungal activities, tetrahydro benzocycloheptane and many terpenoid compounds. 6-methoxy-2-tetralone is more expensive, difficult to synthesize, and unstable in comparison to 6-methoxy-1-tetralone[1].

Chemical Properties

light yellow-beige to orange

Uses

6-Methoxy-3,4-dihydro-2(1H)-naphthalenone was used in the synthesis of 1, 2, 3, 4-tetrahydro-2-naphthylamine derivatives.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 9, p. 267, 1961 DOI: 10.1248/cpb.9.267
The Journal of Organic Chemistry, 26, p. 3237, 1961 DOI: 10.1021/jo01067a049

Synthesis

To a suspension of MCPBA (1.5g, 8.7mmol) in dry dichloromethane (16mL), cooled in ice, was added dihydro naphthalene (616mg, 3.8mmol) dissolved in dichloromethane (2mL). The reaction mixture was stirred overnight, filtered, diluted with dichloromethane, washed with a solution of sodium bicarbonate (5%), brine, dried, and evaporated to obtain an oil (591mg), which without purification was dissolved in ethanol (3mL) and treated with sulfuric acid (3mL, 10%) and heated under reflux for 3 hours. The reaction mixture was cooled, diluted with water, and extracted three times using chloroform. The organic extracts were washed with brine, dried, and evaporated to obtain an oil which, on purification (eluent hexane: ether 7:3), afforded 6-Methoxy-2-tetralone.

References

[1] Banerjee, A. K. et al. “A concise approach for the synthesis of 6-methoxy-2-tetralone.” 2018. 0.

6-Methoxy-2-tetralone synthesis

6099-04-3
2472-22-2
Synthesis of 6-Methoxy-2-tetralone from 3-Methoxycinnamic acid

6-Methoxy-2-tetralone Preparation Products And Raw materials

Raw materials

Preparation Products

6-Methoxy-2-tetralone Suppliers

Global Suppliers ( 213)
Supplier Tel Email Country ProdList Advantage
Bejing Famous Pharmaceutical Technology Co., Ltd. 010-80339217; 13331045123 2559355526@qq.com China 14180 58
TAIZHOU HAIYING PHARMTECH CO.,LTD 0523-0523-86222516 13382003766 sales@haiyingchem.com China 36 58
Nanjing Yingkun Chemical Co.,Ltd. 025-83212803 13382023051;13382003766 sales@yingkunchem.cn China 44 58
Shanghai Boyle Chemical Co., Ltd. 021-50182298 021-50180596 sales@boylechem.com China 2202 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Supplier Advantage
Bejing Famous Pharmaceutical Technology Co., Ltd. 58
TAIZHOU HAIYING PHARMTECH CO.,LTD 58
Nanjing Yingkun Chemical Co.,Ltd. 58
Shanghai Boyle Chemical Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61

View Latest Price from 6-Methoxy-2-tetralone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-Methoxy-3,4-dihydronaphthalen-2(1H)-on pictures 2026-08-25 6-Methoxy-3,4-dihydronaphthalen-2(1H)-on
2472-22-2
 $2.20-8.80 1kg 99% 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
6-Methoxy-2-tetralone pictures 2026-06-30 6-Methoxy-2-tetralone
2472-22-2
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
6-Methoxy-2-tetralone pictures 2026-03-20 6-Methoxy-2-tetralone
2472-22-2
 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd

6-Methoxy-2-tetralone Spectrum

6-Methoxy-2-tetralone(2472-22-2)MS6-Methoxy-2-tetralone(2472-22-2)1HNMR6-Methoxy-2-tetralone(2472-22-2)13CNMR6-Methoxy-2-tetralone(2472-22-2)IR1

2472-22-2 (6-Methoxy-2-tetralone ) Related Search:

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5,8-Dimethoxy-2-tetralone 5-Chloro-8-methoxyl-2-tetralone 5-METHOXY-1-TETRALONE,5-Methoxy-1-tetralone,97%,5-METHOXY-1-TETRALONE 97%,5-METHOXY-1-TETRALONE TECH 94+% 6-methoxy-1-tetralone 7-Methoxy-2-Tetralone(7-OHO),7-METHOXY-2-TETRALONE
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3,4-DIHYDRO-6-METHOXY-2(1H)-NAPHTHALENONE 6-methoxy-1,2,3,4-tetrahydronaphthalen-2-one 6-Methoxy-3,4-dihydro-2(1H)-naphthalenone, 95% 6-Methoxy-2-tetralone,tech.90% 6-methoxy-3,4-dihydro-1H-naphthalene-2-one 3,4-Dihydro-6-methoxynaphthalen-2(1H)-one 6-methoxy-2-Tetrlone 6-methoxy-3,4-dihydronaphthalen-2-one 6-METHOXY-2-TETRALONE: TECH., 90% 6-METHOXY-2-TETRALONE 95% 6-methoxyl-2-tetralone 6-Methoxy-1,2,3,4-tetrahydronaphthalene-2-one 6-Methoxy-2-tetralone,98% 6-Methoxy-2-tetralone,90% 4-dihydro-6-Methoxy- 6-Methoxy-2-tetralone, 6-Methoxy-2-oxo-1,2,3,4-tetrahydronaphthalene 6-Methoxy-2-tetralone, technical, 90% 6-METHOXY-3,4-DIHYDRO-1H-NAPHTHALEN-2-ONE 6-METHOXY-2-TETRALONE 2(1H)-NAPHTHALENONE, 3,4-DIHYDRO-6-METHOXY- 6-Methoxy-2-tetralone> 6-Methoxy-3,4-dihydronaphthalen-2(1H)-on 6-Methoxy-3,4-dihydro-2(1H)-naphthalenone 6-Methoxy-2-tetralone, tech. 97% 6-methoxy-1,2,3,4-tetrahydronaphthalen-2-one - [M85911] 6-Methoxy-3,4-dihydro-2(1H)-naphthalenone Compound Fr12288 6-Methoxytetralin-2-one 6-METHOXY-3,4-DIHYDRONAPHTHALEN-2(1H)-ONE 2472-22-2 Organic Building Blocks Ketones Building Blocks C11 to C12 Carbonyl Compounds Fused Ring Systems pharmacetical Naphthalenes