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5-CHLOROBENZOTHIOPHENE

5-CHLOROBENZOTHIOPHENE Structure
5-CHLOROBENZOTHIOPHENE structure
CAS No.
20532-33-6
Chemical Name:
5-CHLOROBENZOTHIOPHENE
Synonyms
5-Chlorobenzo[b]thiophene;6-chlorobenzo[b]thiophene;5-Chlorothionaphthene;5-CHLOROBENZOTHIOPHENE;5-chloro-1-benzothiophene;5-chlorine Benzothiophene;5-Chlorobenzothiophene ,98%;Benzo[b]thiophene, 5-chloro-;5-Chlorobenzothiophene in isooctane;5-chlorine thiofuran-2-carboxylic acid
CBNumber:
CB4334138
Molecular Formula:
C8H5ClS
Molecular Weight:
168.64
MDL Number:
MFCD00055623
MOL File:
20532-33-6.mol
MSDS File:
SDS
Last updated:2026-05-28 05:21:37
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5-CHLOROBENZOTHIOPHENE Properties

Boiling point 85 °C(Press: 4 Torr)
Density 1.349±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Solid
color Off-white
Water Solubility Slightly soluble in water.

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Risk Statements  36/37/38
Safety Statements  26-37/39
HS Code  29339900
NFPA 704
1
2 0

5-CHLOROBENZOTHIOPHENE price More Price(56)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AstaTech 58062 5-CHLORO-BENZO[B]THIOPHENE 97% 20532-33-6 5G $37 2026-04-30 Buy
AstaTech 58062 5-CHLORO-BENZO[B]THIOPHENE 97% 20532-33-6 25G $169 2026-04-30 Buy
AstaTech 58062 5-CHLORO-BENZO[B]THIOPHENE 97% 20532-33-6 100G $524 2026-04-30 Buy
Activate Scientific AS31201 5-Chlorobenzothiophene 97% 20532-33-6 1g $24 2026-06-04 Buy
Activate Scientific AS31201 5-Chlorobenzothiophene 97% 20532-33-6 5g $39 2026-06-04 Buy
Product number Packaging Price Buy
58062 5G $37 Buy
58062 25G $169 Buy
58062 100G $524 Buy
AS31201 1g $24 Buy
AS31201 5g $39 Buy

5-CHLOROBENZOTHIOPHENE Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

5-Chlorobenzo[b]thiophene is used as pharmaceutical intermediate.

Synthesis

Benzene, 1-chloro-4-[(2,2-diethoxyethyl)thio]-

50548-46-4

5-CHLOROBENZOTHIOPHENE

20532-33-6

To a 25 mL round-bottomed flask was added (4-chlorophenyl)(2,2-diethoxyethyl)thiane (500 mg, 1.92 mmol) and chlorobenzene (2 mL). The resulting mixture was added dropwise to a boiling solution of chlorobenzene (5 mL) in polyphosphoric acid (1 g) over 5 min. After completion of the reaction, the mixture was slowly poured into ice water (25 mL) and extracted three times with ethyl acetate (25 mL). The organic phases were combined, washed with saturated saline (50 mL) and dried over anhydrous sodium sulfate. The organic phases were concentrated under reduced pressure, and the resulting crude product was purified by silica gel column chromatography, using petroleum ether as eluent, to give 5-chlorobenzothiophene (290 mg, 90% yield) as an off-white solid.

References

[1] Patent: US2008/21026, 2008, A1. Location in patent: Page/Page column 17; 27
[2] Patent: CN103896967, 2016, B. Location in patent: Paragraph 0048; 0052-0054
[3] Journal of Organic Chemistry, 1995, vol. 60, # 7, p. 1936 - 1938
[4] Phosphorus, Sulfur and Silicon and the Related Elements, 1994, vol. 96, # 1-4, p. 441 - 444
[5] Bioorganic and medicinal chemistry, 2004, vol. 12, # 9, p. 2251 - 2273

5-CHLOROBENZOTHIOPHENE Preparation Products And Raw materials

Raw materials

Toluene Sodium 4-Chlorothiophenol polyphosphoric acid Bromoacetaldehyde dimethyl acetal
Chlorobenzene Methanol Benzene, 1-chloro-4-[(2,2-diethoxyethyl)thio]- 15-PHENYLPENTADECANOIC ACID

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Preparation Products

5-Chloro-1-benzothiophene-2-carbaldehyde

5-CHLOROBENZOTHIOPHENE Suppliers

Global( 128)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Nanjing Habo Medical Technology Co., Ltd. 13376080562 13376090521 sales@habotech.com China 726 60
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chembon Pharmaceutical Co., Ltd. 028-84252981 18583719936 sales@chembon.com.cn China 854 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Alfa Aesar 84
Energy Chemical 61
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Nanjing Habo Medical Technology Co., Ltd. 60
Adamas Reagent, Ltd. 59
Shanghai Longsheng chemical Co.,Ltd. 59
Shanghai Hanhong Scientific Co.,Ltd. 64
Chembon Pharmaceutical Co., Ltd. 64
Shandong Xiya Chemical Co., Ltd 57

View Lastest Price from 5-CHLOROBENZOTHIOPHENE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-CHLOROBENZOTHIOPHENE pictures 2026-08-20 5-CHLOROBENZOTHIOPHENE
20532-33-6
 $1.10 1g 99.00% 100 Tons Dideu Industries Group Limited
5-CHLOROBENZOTHIOPHENE pictures 2019-07-10 5-CHLOROBENZOTHIOPHENE
20532-33-6
 $1.00 1KG 98% 150KG Career Henan Chemical Co

5-CHLOROBENZOTHIOPHENE Spectrum

5-CHLOROBENZOTHIOPHENE(20532-33-6)1HNMR

20532-33-6(5-CHLOROBENZOTHIOPHENE)Related Search:

METHYL 5-CHLORO-1-BENZOTHIOPHENE-2-CARBOXYLATE 5-CHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID 5-CHLORO-3-METHYLBENZO[B]THIOPHENE-2-SULFONAMIDE 2-ACETYL-5-CHLORO-3-METHYLTHIANAPHTHENE 5-CHLORO-3-METHYLBENZO[B]THIOPHENE-2-SULFONYL CHLORIDE
[(5-CHLOROBENZO[B]THIOPHEN-3-YL)METHYL](TRIPHENYL)PHOSPHONIUM BROMIDE 2-BROMO-1-(5-CHLORO-3-METHYLBENZO[B]THIOPHEN-2-YL)ETHAN-1-ONE 5-CHLOROBENZOTHIOPHENE-3-METHYLAMINE 2-BROMO-5-CHLORO-3-METHYLBENZO[B]THIOPHENE 2-(5-CHLORO-3-METHYLBENZO[B]THIOPHEN-2-YL)ACETIC ACID
5-CHLORO-3-METHYLBENZO[B]THIOPHENE 5-CHLOROBENZOTHIOPHENE-3-ACETIC ACID,2-(5-CHLOROBENZOTHIOPHENE-3-YL)ACETIC ACID 5-Chlorobenzothiophene-3-acetonitrile,2-(5-CHLOROBENZOTHIOPHENE-3-YL)ACETONITRILE 5-CHLORO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID 5-CHLOROBENZOTHIOPHENE
7-CHLORO-3-METHYLBENZO[B]THIOPHENE METHYL 3-CHLOROBENZO[B]THIOPHENE-2-CARBOXYLATE 3-(Bromomethyl)-5-chlorobenzo[b]thiophene

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5-CHLOROBENZOTHIOPHENE 5-chlorine Benzothiophene 5-Chlorobenzothiophene ,98% 5-Chlorothionaphthene 5-chloro-1-benzothiophene 5-chlorine thiofuran-2-carboxylic acid Benzo[b]thiophene, 5-chloro- 5-CHLOROBENZOTHIOPHENE ISO 9001：2015 REACH 5-Chlorobenzothiophene in isooctane 5-Chlorobenzo[b]thiophene 6-chlorobenzo[b]thiophene 20532-33-6 C8H5ClS