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2-N-Boc-amino-3-formylpyridine

2-N-Boc-amino-3-formylpyridine Structure
2-N-Boc-amino-3-formylpyridine structure
CAS No.
116026-94-9
Chemical Name:
2-N-Boc-amino-3-formylpyridine
Synonyms
margin: 0px;padding: 0px;color: rgb(255, 0, 0);">-3-pyridinecarboxaldehyde;2-BOC-AMINO-3-FORMYLPYRIDINE;2-N-BOC-AMINO-3-FORMYLPYRIDINE;REF DUPL: 2-N-Boc-amino-3-formylpyridine;TERT-BUTYL 3-FORMYLPYRIDIN-2-YLCARBAMATE;ert-butylN-(3-formylpyridin-2-yl)carbamate;tert-butyl N-(3-forMylpyridin-2-yl)carbaMate
CBNumber:
CB4337104
Molecular Formula:
C11H14N2O3
Molecular Weight:
222.24
MDL Number:
MFCD03086225
MOL File:
116026-94-9.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:43
Product description Number Pack Size Price
2-N-Boc-amino-3-formylpyridine B619105 1g $380
tert-Butyl(3-formylpyridin-2-yl)carbamate 95+% 36062 1g $480
tert-Butyl(3-formylpyridin-2-yl)carbamate 98% CD11343609 10g $495
tert-Butyl(3-formylpyridin-2-yl)carbamate 116026949 10g $525
tert-Butyl(3-formylpyridin-2-yl)carbamate 98% CM105385 10g $468
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2-N-Boc-amino-3-formylpyridine Properties

Melting point 109-111 °C
Boiling point 310 °C
Density 1.212
Flash point 141 °C
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 12.05±0.70(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

2-N-Boc-amino-3-formylpyridine price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B619105 2-N-Boc-amino-3-formylpyridine 116026-94-9 1g $380 2021-12-16 Buy
Medical Isotopes, Inc. 36062 tert-Butyl(3-formylpyridin-2-yl)carbamate 95+% 116026-94-9 1g $480 2021-12-16 Buy
Crysdot CD11343609 tert-Butyl(3-formylpyridin-2-yl)carbamate 98% 116026-94-9 10g $495 2021-12-16 Buy
Alichem 116026949 tert-Butyl(3-formylpyridin-2-yl)carbamate 116026-94-9 10g $525 2021-12-16 Buy
Chemenu CM105385 tert-Butyl(3-formylpyridin-2-yl)carbamate 98% 116026-94-9 10g $468 2021-12-16 Buy
Product number Packaging Price Buy
B619105 1g $380 Buy
36062 1g $480 Buy
CD11343609 10g $495 Buy
116026949 10g $525 Buy
CM105385 10g $468 Buy

2-N-Boc-amino-3-formylpyridine Chemical Properties,Uses,Production

Uses

2-Boc-amino-3-pyridinecarboxaldehyde can be used as a pharmaceutical synthesis intermediate. It can be prepared by reacting 2-aminopyridine with (Boc)2O protecting group to prepare intermediate 2-(tert-butyloxycarbonylamino)pyridine, which is then reacted with tert-butyllithium and DMF to obtain the final product.

Synthesis

2-(TERT-BUTOXYCARBONYLAMINO)PYRIDINE

38427-94-0

N,N-Dimethylformamide

68-12-2

2-N-Boc-amino-3-formylpyridine

116026-94-9

Step 2: Synthesis of tert-butyl 3-formylpyridin-2-ylcarbamate (9b) To a solution of compound 9a (14.0 g, 72 mmol) in anhydrous ether (500 mL) at -78 °C and under nitrogen protection, tert-butyllithium (1.7 M, 106 mL, 180 mmol) was slowly added. The reaction mixture was slowly warmed to 0 °C and stirred at this temperature for 1 hour. Subsequently, anhydrous N,N-dimethylformamide (8.0 mL, 103 mmol) was added rapidly under vigorous stirring. The reaction mixture was continued to be stirred at 0 °C for 10 min and then quenched with a half-saturated aqueous ammonium chloride solution. The aqueous layer was separated and extracted twice with ethyl acetate (EA). The organic layers were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by column chromatography (eluent: petroleum ether/ethyl acetate = 3/1) to afford the target product 9b (8.0 g, 52% yield) as a white solid.

References

[1] Patent: WO2013/64231, 2013, A1. Location in patent: Page/Page column 45
[2] Heterocyclic Communications, 2011, vol. 17, # 1-2, p. 21 - 23

2-N-Boc-amino-3-formylpyridine Preparation Products And Raw materials

Raw materials

2-(TERT-BUTOXYCARBONYLAMINO)PYRIDINE N,N-Dimethylformamide tert-Butyllithium Diethyl ether

Preparation Products

2-N-Boc-amino-3-formylpyridine Suppliers

Global( 74)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30227 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23541 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 18895 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52705 58
Wuhan Demeikai Biotechnology Co., Ltd 		+8618942921723 info@dmksw.xin China 717 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
Golden Pharma Co., Limited 		+undefined18958062155 sales@zjgoldpharm.com China 5899 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
Supplier Advantage
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Career Henan Chemica Co 		58
ANHUI WITOP BIOTECH CO., LTD 		58
Dideu Industries Group Limited 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
Wuhan Demeikai Biotechnology Co., Ltd 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Golden Pharma Co., Limited 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58

View Lastest Price from 2-N-Boc-amino-3-formylpyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-N-Boc-amino-3-formylpyridine pictures 2025-11-18 2-N-Boc-amino-3-formylpyridine
116026-94-9
 US $1.10 / g 1g 99.00% 100 Tons Min Dideu Industries Group Limited

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Carbamic acid, N-(3-formyl-2-pyridinyl)-, 1,1-dimethylethyl ester tert-butyl N-(3-forMylpyridin-2-yl)carbaMate 2-N-BOC-AMINO-3-FORMYLPYRIDINE 2-BOC-AMINO-3-FORMYLPYRIDINE (3-FORMYL-PYRIDIN-2-YL)-CARBAMIC ACID TERT-BUTYL ESTER TERT-BUTYL 3-FORMYLPYRIDIN-2-YLCARBAMATE REF DUPL: 2-N-Boc-amino-3-formylpyridine ert-butylN-(3-formylpyridin-2-yl)carbamate 2-N-Boc-amino-3-formylpyridine ISO 9001：2015 REACH 2--3-pyridinecarboxaldehyde ">-3-pyridinecarboxaldehyde 2-