3-Phenylbenzenesulfonyl chloride
- CAS No.
- 65685-01-0
- Chemical Name:
- 3-Phenylbenzenesulfonyl chloride
- Synonyms
- BIPHENYL-3-SULFONYL CHLORIDE;Biphenyl-3-sulphonyl chloride;3-Phenylbenzenesulfonyl chloride;1,1'-biphenyl-3-sulfonyl chloride;3-PHENYLBENZENESULPHONYL CHLORIDE;1,1'-Biphenyl]-3-sulfonyl chloride;3-phenylbenzene-1-sulfonyl chloride;1,1'-Biphenyl]-3-sulfonyl chloride (9CI, ACI);3-PHENYLBENZENESULFONYL CHLORIDE ISO 9001：2015 REACH;3-Phenylbenzenesulphonyl chloride, 3-(Chlorosulphonyl)biphenyl
- CBNumber:
- CB4338606
- Molecular Formula:
- C12H9ClO2S
- Molecular Weight:
- 252.72
- MDL Number:
- MFCD01631880
- MOL File:
- 65685-01-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P260-P280-P303+P361+P353-P301+P330+P331-P304+P340+P310-P305+P351+P338+P310 |
| Hazard Codes | C,Xi |
| Risk Statements | 36 |
| Safety Statements | 26 |
| RIDADR | UN3261 |
| Hazard Note | Corrosive |
| HazardClass | 8 |
| HS Code | 2904990090 |
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
3-Phenylbenzenesulfonyl chloride price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 288083 | 3-Phenylbenzenesulfonyl chloride Asreported | 65685-01-0 | 250mg | $382 | 2026-06-03 | Buy |
| Usbiological | 288083 | 3-Phenylbenzenesulfonyl chloride Asreported | 65685-01-0 | 500mg | $531 | 2026-06-03 | Buy |
| Usbiological | 288083 | 3-Phenylbenzenesulfonyl chloride Asreported | 65685-01-0 | 1g | $968 | 2026-06-03 | Buy |
| Usbiological | 288083 | 3-Phenylbenzenesulfonyl chloride Asreported | 65685-01-0 | 2g | $1387 | 2026-06-03 | Buy |
| Usbiological | 288083 | 3-Phenylbenzenesulfonyl chloride Asreported | 65685-01-0 | 5g | $2013 | 2026-06-03 | Buy |
3-Phenylbenzenesulfonyl chloride Chemical Properties, Uses, Production
Synthesis
![1,1'-Biphenyl, 3-[(phenylmethyl)thio]-](/CAS/20210305/GIF/94306-39-5.gif)
94306-39-5
65685-01-0
[1,1'-Biphenyl]-3-yl(benzyl)thiolane (450 mg, 1.63 mmol) was used as a raw material to synthesize [1,1'-biphenyl]-3-sulfonyl chloride according to General Method J. The synthesis was carried out by using a mixture of acetic acid/water (3:1, v/v; 0.1 mmol/mL) and N-chlorobutanediyl chloride (3:1, v/v; 0.1 mmol/mL). The procedure was as follows: the raw material was dissolved in a mixed solvent of acetic acid/water (3:1, v/v; 0.1 mmol/mL) at room temperature, and N-chlorosuccinimide (NCS, 6 equiv) was added. The reaction mixture was stirred at the same temperature for 3-6 h. The reaction progress was monitored by HPLC. After completion of the reaction, the solvent was removed by concentration under reduced pressure, saturated aqueous sodium bicarbonate was added and extracted with ethyl acetate (EtOAc). The organic layers were combined, washed with saturated brine and dried over anhydrous sodium sulfate. After filtration, the crude product was concentrated under reduced pressure and purified by Combifiash silica gel column chromatography (100% hexane as eluent) to afford [1,1'-biphenyl]-3-sulfonyl chloride 250 mg (5.9% yield) as a colorless solid. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 8.28-8.24 (m, 1H), 8.05-8.01 (m, 1H), 7.98-7.95 (m, 1H), 7.74-7.68 (m, 1H), 7.66-7.61 (m, 2H), 7.56-7.49 (m, 2H), 7.49- 7.43 (m, 1H).
References
[1] ChemMedChem, 2016, vol. 11, # 23, p. 2607 - 2620
[2] Patent: WO2018/52903, 2018, A1. Location in patent: Page/Page column 22-23; 58
3-Phenylbenzenesulfonyl chloride Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 | |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Wuhan Chemwish Technology Co.， Ltd | 027-67849912 | sales@chemwish.com | China | 9144 | 60 |
| Changzhou Hopschain Chemical Co.,Ltd. | 85528066 13775048983 | sales@hopschem.com | China | 31548 | 55 |
View Latest Price from 3-Phenylbenzenesulfonyl chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-02-26 | Biphenyl-3-sulphonyl chloride
65685-01-0
|
1KG | 99.0%+ | 100 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- Biphenyl-3-sulphonyl chloride
65685-01-0
- 99.0%+
- Shaanxi Dideu Medichem Co. Ltd
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