ChemicalBook >> CAS DataBase List >>N-Chlorosuccinimide
N-Chlorosuccinimide
- CAS No.
- 128-09-6
- Chemical Name:
- N-Chlorosuccinimide
- Synonyms
- NCS;Chlorosuccinimide;N-CHLOROSUCCINAMIDE;N-Chlorosuccinimide≥ 99% (Iodometric Titration);SUCCINCHLORIMIDE;N-Chlorosuccinimide (NCS);N-ChlorosucciniMide, 98.5%;1-Chloro-2,5-piperidinedione;NSC 8748;orosuccinimide
- CBNumber:
- CB7141683
- Molecular Formula:
- C4H4ClNO2
- Molecular Weight:
- 133.53
- MDL Number:
- MFCD00005511
- MOL File:
- 128-09-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-06-04 16:00:12
| Product description | Number | Pack Size | Price |
| N-Chlorosuccinimide for synthesis | 8.02811 | 5G | $41.8 |
| N-Chlorosuccinimide for synthesis | 8.02811 | 250g | $97 |
| N-Chlorosuccinimide 98% | 109681 | 100g | $36.3 |
| N-Chlorosuccinimide 98% | 109681 | 500g | $114 |
| N-Chlorosuccinimide >98.0%(T) | C0291 | 25g | $17 |
| More product size | |||
| Melting point | 148-150 °C (lit.) |
|---|---|
| Density | 1,65 g/cm3 |
| bulk density | 600kg/m3 |
| vapor pressure | 1.04Pa at 25℃ |
| refractive index | 1.4378 (estimate) |
| Flash point | >110°C |
| storage temp. | Store at +2°C to +8°C. |
| solubility | 14g/l |
| pka | -2.78±0.20(Predicted) |
| form | Crystalline Powder |
| color | White |
| Odor | chlorine odor |
| Water Solubility | Soluble in water, alcohol, benzene, acetone and acetic acid. Slightly soluble in ether, chloroform, carbon tetrachloride and petroleum ether. |
| Sensitive | Moisture Sensitive |
| Merck | 14,2164 |
| Boiling point | 216.5°C |
| BRN | 113915 |
| InChI | 1S/C4H4ClNO2/c5-6-3(7)1-2-4(6)8/h1-2H2 |
| InChIKey | JRNVZBWKYDBUCA-UHFFFAOYSA-N |
| SMILES | ClN1C(=O)CCC1=O |
| LogP | -1.19 |
| CAS DataBase Reference | 128-09-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 0FWP306H7X |
| NIST Chemistry Reference | N-Chlorosuccinimide(128-09-6) |
| EPA Substance Registry System | N-Chlorosuccinimide (128-09-6) |
| UNSPSC Code | 12352115 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H290-H302-H314-H335-H410 | |||||||||
| Precautionary statements | P260-P273-P280-P301+P312-P303+P361+P353-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | C,Xi | |||||||||
| Risk Statements | 22-34 | |||||||||
| Safety Statements | 26-36/37/39-45-37/39 | |||||||||
| RIDADR | UN 3261 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UY1013500 | |||||||||
| F | 21 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29251995 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 1 Eye Dam. 1 Met. Corr. 1 Skin Corr. 1B STOT SE 3 |
|||||||||
| Hazardous Substances Data | 128-09-6(Hazardous Substances Data) | |||||||||
| Toxicity | MLD orally in rats: 2.7 g/kg (Stohlman, Smith) | |||||||||
| REACH Registrations | Active | |||||||||
| Limited Quantities | 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
N-Chlorosuccinimide price More Price(82)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.02811 | N-Chlorosuccinimide for synthesis | 128-09-6 | 5G | $41.8 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.02811 | N-Chlorosuccinimide for synthesis | 128-09-6 | 250g | $97 | 2026-04-30 | Buy |
| Sigma-Aldrich | 109681 | N-Chlorosuccinimide 98% | 128-09-6 | 100g | $36.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | 109681 | N-Chlorosuccinimide 98% | 128-09-6 | 500g | $114 | 2026-04-30 | Buy |
| TCI Chemical | C0291 | N-Chlorosuccinimide >98.0%(T) | 128-09-6 | 25g | $17 | 2026-04-30 | Buy |
N-Chlorosuccinimide Chemical Properties,Uses,Production
Chemical Properties
white crystalline powder
Uses
N-Chlorosuccinimide is a chlorinating agent for the side-chain halogenation of alkylarenes. It is used frequently for the side-chain chlorination of sensitive hetarenes.
Uses
N-Chlorosuccinimide (NCS) is a chlorinating and oxidizing reagent. It is more efficient when compared to other chlorinating agents, such as 1,3-dichloro-5,5-dimethylhydantoin (NDDH) and trichloroisocyanuric acid (TCCA) due to its high regioselectivity.
N-Chlorosuccinimide is used as a chlorinating agent, mild oxidant and swimming pool disinfectant. It is used in the microdetermination of hydrazine salts by titrimetry as well as in the detection of arsenic in the +3 oxidative state. It is also employed in the production of rubber additives. Further, it is used as pharmaceutical intermediate and antibiotic drugs intermediate.
Definition
ChEBI: N-chlorosuccinimide is a five-membered cyclic dicarboximide compound having a chloro substituent on the nitrogen atom. It is a pyrrolidinone and a dicarboximide. It derives from a succinimide.
Flammability and Explosibility
Non flammable
reaction suitability
reagent type: oxidant
N-Chlorosuccinimide Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
5-Amino-2,3-dichloropyridine
5-CHLORO-2'-DEOXYURIDINE
5-Methyl-3-phenylisoxazole-4-carboxylic acid
Tau-fluvalinate
2-CHLORO-4-(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE
3-Chloro-2-hydroxy-5-nitropyridine
(2-BUTYL-5-CHLORO-1H-IMIDAZOL-4-YL)METHANOL
Cefaclor monohydrate
3-(2,6-DICHLOROPHENYL)-5-METHYLISOXAZOLE-4-CARBALDEHYDE
2-Amino-5-chlorobenzonitrile
2-ETHYLCYCLOHEXANONE
Ethyl 2-amino-4-phenyl-5-thiazolecarboxylate
2-Chloro-1,4-diaminobenzene
2,3-DICHLORO-5-NITROPYRIDINE
5,6-DICHLORONICOTINIC ACID ETHYL ESTER
1of5
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Dideu Industries Group Limited | +8617392712697 | 1022@dideu.com | China | 29095 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 | sales1@chuanghaibio.com | China | 5216 | 58 |
| HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +86-15350851019; +86-15383190639 | admin@86-ss.com | China | 996 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21533 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10399 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2949 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 | sales@amoychem.com | China | 6339 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 |
Related articles
- The Efficacy and Applications of N-Chlorosuccinimide: A Comprehensive Insight
- N-Chlorosuccinimide (1-chloropyrrolidine-2,5-dione;NCS) was first synthesized in 1886 by the chlorination of succinimide with ....
- Dec 3,2024
- What is N-Chlorosuccinimide?
- N-Chlorosuccinimide (NCS) is a chlorinating and oxidizing reagent. It is also used as a mild oxidant. NCS is related to succin....
- Mar 25,2021
Related Questions
Ask a questionQ:How does N-Chlorosuccinimide work as chlorine source?Charlie - May 9,2026
A:N-Chlorosuccinimide (NCS) is a chlorinating and oxidizing agent
that is used as source for chlorine in radical reactions and various electrophilic additions. Mechanistic experiments implicate a reaction pathway that proceeds via a
single electron oxidation of NCS that amplifies the electrophilicity of
the chlorine atom.
View Lastest Price from N-Chlorosuccinimide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-26 | N-Chlorosuccinimide
128-09-6
|
$5.00 | 1kg | ≥98% | 500mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2026-08-26 | N-Chlorosuccinimide
128-09-6
|
$80.00-99.00 | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
 |
2026-08-26 | N-Chlorosuccinimide
128-09-6
|
$6.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd |
-
- N-Chlorosuccinimide
128-09-6
- $5.00
- ≥98%
- Jinan Finer Chemical Co., Ltd
-
- N-Chlorosuccinimide
128-09-6
- $80.00-99.00
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- N-Chlorosuccinimide
128-09-6
- $6.00
- 99%
- Henan Fengda Chemical Co., Ltd
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128-09-6
