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5-FLUOROBENZO[D]OXAZOLE-2-THIOL

5-FLUOROBENZO[D]OXAZOLE-2-THIOL structure

CAS No.: 13451-78-0

Chemical Name:: 5-FLUOROBENZO[D]OXAZOLE-2-THIOL

Synonyms: 5-Fluorobenzoxazole-2-thiol;5-Fluorobenzo[d]oxazol-2-thiol;2-Mercapto-5-fluorobenzoxazole;5-Fluorobenzoxazole-2-thiol 97%;5-FLUOROBENZO[D]OXAZOLE-2-THIOL;5-Fluoro-2(3H)-benzoxazolethiene;5-Fluorobenzoxazole-2(3H)-thione;5-Fluorobenzoxazole-2-thiol, 97%,;2(3H)-Benzoxazolethione, 5-fluoro-;5-Fluorobenzoxazole-2-thiol

CBNumber:: CB4341448

Molecular Formula:: C7H4FNOS

Molecular Weight:: 169.18

MDL Number:: MFCD08447021

MOL File:: 13451-78-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:49:19

Product description	Number	Pack Size	Price
5-Fluorobenzoxazole-2-thiol 97%	699969	1g	$72.1
5-Fluorobenzo[d]oxazole-2-thiol Asreported	277949	500mg	$333
5-Fluorobenzo[d]oxazole-2-thiol Asreported	277949	1g	$456
5-Fluorobenzo[d]oxazole-2-thiol Asreported	277949	2g	$649
5-Fluorobenzo[d]oxazole-2-thiol Asreported	277949	5g	$877
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5-FLUOROBENZO[D]OXAZOLE-2-THIOL Properties

Melting point	238-240℃
Boiling point	238.8±42.0 °C(Predicted)
Density	1.51±0.1 g/cm3(Predicted)
storage temp.	2-8°C
pka	10.10±0.20(Predicted)
form	powder
Appearance	Off-white to pink Solid
Sensitive	Moisture & Light Sensitive
InChI	1S/C7H4FNOS/c8-4-1-2-6-5(3-4)9-7(11)10-6/h1-3H,(H,9,11)
InChIKey	UVHVJSJZCPFGET-UHFFFAOYSA-N
SMILES	Fc1ccc2oc(S)nc2c1
CAS DataBase Reference	13451-78-0
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Danger

Hazard statements

H302-H318

Precautionary statements

P280-P301+P312+P330-P305+P351+P338+P310

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

22-41

Safety Statements

26-39-24/25

WGK Germany

HS Code

29349990

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Eye Dam. 1

NFPA 704

	1
2		0

5-FLUOROBENZO[D]OXAZOLE-2-THIOL price More Price(48)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	699969	5-Fluorobenzoxazole-2-thiol 97%	13451-78-0	1g	$72.1	2023-06-20	Buy
Usbiological	277949	5-Fluorobenzo[d]oxazole-2-thiol Asreported	13451-78-0	500mg	$333	2026-06-03	Buy
Usbiological	277949	5-Fluorobenzo[d]oxazole-2-thiol Asreported	13451-78-0	1g	$456	2026-06-03	Buy
Usbiological	277949	5-Fluorobenzo[d]oxazole-2-thiol Asreported	13451-78-0	2g	$649	2026-06-03	Buy
Usbiological	277949	5-Fluorobenzo[d]oxazole-2-thiol Asreported	13451-78-0	5g	$877	2026-06-03	Buy

Product number	Packaging	Price	Buy
699969	1g	$72.1	Buy
277949	500mg	$333	Buy
277949	1g	$456	Buy
277949	2g	$649	Buy
277949	5g	$877	Buy

5-FLUOROBENZO[D]OXAZOLE-2-THIOL Chemical Properties,Uses,Production

Synthesis

75-15-0

399-97-3

13451-78-0

2-Amino-4-fluorophenol (10 g, 78.8 mmol), carbon disulfide (35 mL) and potassium hydroxide (5.3 g, 94.6 mmol) were mixed in ethanol (200 mL) and heated to reflux the reaction overnight. Upon completion of the reaction, the reaction mixture was concentrated to dryness and subsequently diluted with water. The diluted solution was neutralized with 1 M hydrochloric acid solution and then extracted several times with ethyl acetate. The organic phases were combined, washed with saturated brine, dried over anhydrous sodium sulfate, and finally concentrated under vacuum to give 5-fluorobenzo[d]oxazole-2-thiol 9.3 g in 70% yield. The product was identified by 1H NMR (300MHz, DMSO-d6): δ7.51 (ddd, J=8.8,4.2,0.6Hz, 1H), 7.15-7.04 (m, 2H), 3.31 (brs, 1H). lC-MS (m/z): 170.2.

References

[1] Patent: WO2017/23941, 2017, A1. Location in patent: Page/Page column 50; 51
[2] Journal of Medicinal Chemistry, 1994, vol. 37, # 7, p. 913 - 923
[3] Journal of Medicinal Chemistry, 1998, vol. 41, # 16, p. 3015 - 3021
[4] Bioorganic and Medicinal Chemistry, 2007, vol. 15, # 10, p. 3515 - 3523
[5] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 9, p. 3044 - 3049

5-FLUOROBENZO[D]OXAZOLE-2-THIOL synthesis

Synthesis of 5-FLUOROBENZO[D]OXAZOLE-2-THIOL from 2-AMINO-4-FLUOROPHENOL and Potassium ethylxanthate

5-FLUOROBENZO[D]OXAZOLE-2-THIOL Preparation Products And Raw materials

Raw materials

Tetramethylthiuram Disulfide Carbon disulfide 2-AMINO-4-FLUOROPHENOL Potassium ethylxanthate Ethanol

Potassium hydroxide

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Preparation Products

5-FLUOROBENZO[D]OXAZOLE-2-THIOL Suppliers

Global( 77)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10399	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2971	58
career henan chemical co	+86-0371-86658258	factory@coreychem.com	China	29780	58
Zhengzhou Alfa Chemical Co.,Ltd	+86-18530059196	sale04@alfachem.cn	China	9636	58
Aladdin Scientific		tp@aladdinsci.com	United States	54746	58
Hebei Chuanghai Biotechnology Co., Ltd	+86-15350571055	Sibel@chuanghaibio.com	China	6084	58
Allfluoro Pharmaceutical Company Limited	+86-400-0216110 +86-15958047586	sales@allfluoro.com	China	11380	58
DAYANG CHEM (HANGZHOU) CO.,LTD	+86-88938639 +86-17705817739	info@dycnchem.com	China	53799	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84

Supplier	Advantage
Shenzhen Nexconn Pharmatechs Ltd	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
career henan chemical co	58
Zhengzhou Alfa Chemical Co.,Ltd	58
Aladdin Scientific	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Allfluoro Pharmaceutical Company Limited	58
DAYANG CHEM (HANGZHOU) CO.,LTD	58
Amadis Chemical Company Limited	58
Alfa Aesar	84

View Lastest Price from 5-FLUOROBENZO[D]OXAZOLE-2-THIOL manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2022-01-15	5-Fluorobenzo[d]oxazole-2-thiol 13451-78-0		1KG	99.2%	100 tons	Honest Joy Holdings Limited
	2020-02-21	5-FLUOROBENZO[D]OXAZOLE-2-THIOL 13451-78-0	$3.00	1KG	98%	200KG	Career Henan Chemical Co

5-Fluorobenzo[d]oxazole-2-thiol
13451-78-0
$0.00
99.2%
Honest Joy Holdings Limited

5-FLUOROBENZO[D]OXAZOLE-2-THIOL
13451-78-0
$3.00
98%
Career Henan Chemical Co

5-FLUOROBENZO[D]OXAZOLE-2-THIOL Spectrum

5-FLUOROBENZO[D]OXAZOLE-2-THIOL(13451-78-0)¹HNMR

13451-78-0(5-FLUOROBENZO[D]OXAZOLE-2-THIOL)Related Search:

5-Fluorobenzoxazole 5-FLUOROBENZO[D]OXAZOLE-2-THIOL 7-Fluorobenzoxazole-2(3H)-thione 6-Chloro-2-benzoxazolethiol 5-BROMOBENZO[D]OXAZOLE-2-THIOL

2-Mercapto-5-methylbenzoxazole

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5-FLUOROBENZO[D]OXAZOLE-2-THIOL 5-Fluoro-2(3H)-benzoxazolethiene 5-Fluorobenzoxazole-2-thiol JR-8607, 5-Fluorobenzo[d]oxazole-2-thiol, 97% 5-Fluorobenzoxazole-2(3H)-thione 2-Mercapto-5-fluorobenzoxazole 5-Fluorobenzoxazole-2-thiol 97% 2(3H)-Benzoxazolethione, 5-fluoro- 5-Fluorobenzoxazole-2-thiol, 97%, 5-Fluorobenzoxazole-2-thiol 5-Fluorobenzo[d]oxazol-2-thiol 13451-78-0 C7H4FNOS