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N-Boc-S-Trityl-L-cysteine

N-Boc-S-Trityl-L-cysteine structure

CAS No.: 21947-98-8

Chemical Name:: N-Boc-S-Trityl-L-cysteine

Synonyms: BOC-L-CYS(TRT)-OH;Boc-Cys(Trt);N-(TERT-BUTOXYCARBONYL)-S-TRITYL-L-CYSTEINE;Boc-S-Trityl-Cys-OH;Boc-Cys(Trt)-OH 97%;BOC-CYSTEINE(TRT)-OH;Boc-Cys(Trt)-OH, >=98%;BOC-L-CYSTEINE(TRITYL);N-Boc-S-Trityl-L-Cys-OH;BOC-L-TRITYL-L-CYSTEINE

CBNumber:: CB4355333

Molecular Formula:: C27H29NO4S

Molecular Weight:: 463.59

MDL Number:: MFCD00038251

MOL File:: 21947-98-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:58:07

Product description	Number	Pack Size	Price
Boc-Cys(Trt)-OH Novabiochem?	8.53005	25g	$290
Boc-Cys(Trt)-OH Novabiochem?	8.53005	100g	$875
Boc-Cys(Trt)-OH 97%	459313	5g	$80
Boc-Cys(Trt)-OH 97%	459313	25g	$336
Boc-Cys(Trt)-OH Asreported	264117	5g	$378
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N-Boc-S-Trityl-L-cysteine Properties

Melting point	143-146 °C(lit.)
alpha	27.5 º (c=1, EtOH)
Boiling point	610.9±55.0 °C(Predicted)
Density	1.200±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Powder
pka	3.82±0.10(Predicted)
color	White to off-white
optical activity	[α]20/D +27.5°, c = 1 in ethanol
BRN	2028965
Major Application	peptide synthesis
InChIKey	JDTOWOURWBDELG-QHCPKHFHSA-N
SMILES	C(O)(=O)[C@H](CSC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)NC(OC(C)(C)C)=O
CAS DataBase Reference	21947-98-8(CAS DataBase Reference)
UNSPSC Code	12352209
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P280-P302+P352

PPE

Eyeshields, Gloves, type N95 (US)

Safety Statements

22-24/25

WGK Germany

3-10

HS Code

2930 90 16

Storage Class

11 - Combustible Solids

NFPA 704

	1
1		0

N-Boc-S-Trityl-L-cysteine price More Price(91)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	8.53005	Boc-Cys(Trt)-OH Novabiochem?	21947-98-8	25g	$290	2026-04-30	Buy
Sigma-Aldrich	8.53005	Boc-Cys(Trt)-OH Novabiochem?	21947-98-8	100g	$875	2026-04-30	Buy
Sigma-Aldrich	459313	Boc-Cys(Trt)-OH 97%	21947-98-8	5g	$80	2026-04-30	Buy
Sigma-Aldrich	459313	Boc-Cys(Trt)-OH 97%	21947-98-8	25g	$336	2026-04-30	Buy
Usbiological	264117	Boc-Cys(Trt)-OH Asreported	21947-98-8	5g	$378	2026-06-03	Buy

Product number	Packaging	Price	Buy
8.53005	25g	$290	Buy
8.53005	100g	$875	Buy
459313	5g	$80	Buy
459313	25g	$336	Buy
264117	5g	$378	Buy

N-Boc-S-Trityl-L-cysteine Chemical Properties,Uses,Production

Chemical Properties

White to yellow crystalline powder

Uses

Boc-Cys(Trt)-OH is used in method for preparing ularitide.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

24424-99-5

2799-07-7

21947-98-8

General procedure for the synthesis of N-tert-butoxycarbonyl-S-trityl-L-cysteine from di-tert-butyl dicarbonate (Boc2O) and S-trityl-L-cysteine: S-trityl-L-cysteine (5 g, 12.7 mmol) was dissolved in 2N NaOH solution (80 mL), followed by the addition of di-tert-butyl dicarbonate (4.5 g, 20 mmol) . The reaction mixture was stirred at room temperature for 24 hours. After completion of the reaction, the aqueous solution was acidified to pH 2 with concentrated hydrochloric acid and then extracted with dichloromethane (2 x 100 mL). The organic phases were combined, washed with brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford the target compound N-tert-butoxycarbonyl-S-trityl-L-cysteine (5.3 g, 90% yield) as a white foamy solid without further purification.1H NMR (DMSO-d6) δ: 1.37 (s, 9H, tert-butyl-CH3); 2.29-2.58 (m , 2H, CH2); 3.76-3.79 (m, 1H, CH); 6.84 (d, J=7.8Hz, 1H, NH); 7.14-7.38 (m, 15H, triphenylmethyl-H).MALDI-TOF MS: m/z 464.8 [M+H]+, molecular weight 463.59 for calculated value C27H29NO4S.

References

[1] European Journal of Medicinal Chemistry, 2012, vol. 50, p. 383 - 392
[2] Chemical Communications, 2013, vol. 49, # 92, p. 10808 - 10810
[3] Patent: CN106432014, 2017, A. Location in patent: Paragraph 0096; 0100; 0101; 0102; 0142; 0146; 0147; 0148
[4] Patent: WO2009/137251, 2009, A2. Location in patent: Page/Page column 30; 31
[5] Chemistry of Natural Compounds, 1979, vol. 15, p. 471 - 476

N-Boc-S-Trityl-L-cysteine Preparation Products And Raw materials

Raw materials

Sodium acetate N,N-Dimethylformamide Acetone Di-tert-butyl dicarbonate Triethylamine

1,4-Dioxane L-Cysteine monohydrochloride Triphenylmethyl Chloride Citric acid S-Trityl-L-cysteine

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Preparation Products

N-Boc-S-Trityl-L-cysteine Suppliers

Global( 333)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd	+8618382028708	ni@enlaibio.com	China	1100	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6366	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-0519-85551759 +8613506123987	marketing1@neostarunited.com	China	8828	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58

Supplier	Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Xiamen AmoyChem Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
SIMAGCHEM CORP	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from N-Boc-S-Trityl-L-cysteine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-06-05	Boc-Cys(Trt)-OH 21947-98-8		1kgkg	98%	1T+	Sichuan HongRi Pharma-Tech Co.,Ltd
2022-01-27	Boc-Cys(Trt)-OH 21947-98-8		1KG	97.5%	100 tons	Honest Joy Holdings Limited
2019-08-08	N-Boc-S-Trityl-L-cysteine 21947-98-8	$7.00	1KG	99%	100kg	Career Henan Chemical Co

Boc-Cys(Trt)-OH
21947-98-8
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

Boc-Cys(Trt)-OH
21947-98-8
$0.00
97.5%
Honest Joy Holdings Limited

N-Boc-S-Trityl-L-cysteine
21947-98-8
$7.00
99%
Career Henan Chemical Co

N-Boc-S-Trityl-L-cysteine Spectrum

N-Boc-S-Trityl-L-cysteine(21947-98-8)¹HNMR N-Boc-S-Trityl-L-cysteine(21947-98-8)IR

21947-98-8(N-Boc-S-Trityl-L-cysteine)Related Search:

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POLY(METHYLSILSESQUIOXANE) tert-Butyl carbazate Trityl candesartan cilexetil L-Cysteine PENICILLIN V

Carbonyl iron powder S-Trityl-L-cysteine Boc-S-trityl-D-cysteine BOC-S-TRITYL-D-CYSTEINE,N-ALPHA-T-BOC-S-TRITYL-D-CYSTEINE,BOC-D-TRITYL-L-CYSTEINE BOC-S-TRITYL-L-CYSTEINE N-HYDROXYSUCCINIMIDE ESTER

BOC-PEN(TRT)-OH BOC-D-PEN(TRT)-OH N-Boc-S-Trityl-L-cysteine

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Boc-S-Trityl-Cys-OH N-(tert-Butyloxycarbonyl)-S-trityl-L-cysteine N-[(1,1-Dimethylethoxy)carbonyl]-S-(triphenylmethyl)-L-cysteine N-Boc-S-Trityl-L-Cys-OH BOC-S-trityl-L-cysteine,99% 2-(tert-butoxycarbonylamino)-3-[tri(phenyl)methylthio]propionic acid 2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[tri(phenyl)methylsulfanyl]propanoic acid L-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]-S-(triphenylmethyl)- N-(tert-Butoxycarbonyl)-S-trityl-L-cysteine ,99% N-Boc-S-triphenylMethyl-L-cysteine tert-butyl N-[(2R)-3-oxo-4,4,4-triphenyl-1-sulfanylbutan-2-yl]carbaMate Boc-S-trityl-L-cysteine≥ 99.5% (HPLC, Chiral purity) Boc-Cys(Trt)-OH 97% Boc-Cys(Trt)-OH, >=98% Nα-Boc-S-trityl-L-cysteine, N-(tert-Butoxycarbonyl)-S-trityl-L-cysteine (R)-2-((tert-Butoxycarbonyl)aMino)-3-(tritylthio)propanoic acid BOC-L-TRITYL-L-CYSTEINE (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-tritylsulfanylpropanoic acid (2R)-2-{[(tert-butoxy)carbonyl]amino}-3-[(triphenylmethyl)sulfanyl]propanoic acid (2R)-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-3-[(triphenylmethyl)thio]propanoic acid BOC-L-CYSTEINE(TRITYL) BOC-CYSTEINE(TRT)-OH BOC-S-TRITYL-L-CYSTEINE (R)-2-TERT-BUTOXYCARBONYLAMINO-3-TRITYLSULFANYL-PROPIONIC ACID N-BOC-S-TRITYL-L-CYSTEINE N-ALPHA-T-BOC-S-TRITYL-L-CYSTEINE N-ALPHA-TERT-BUTYLOXYCARBONYL-S-TRITYL-L-CYSTEINE N-ALPHA-T-BUTOXYCARBONYL-S-TRITYL-L-CYSTEINE N-ALPHA-T-BUTYLOXYCARBONYL-S-TRITYL-L-CYSTEINE N-ALPHA-BOC-S-TRITYL-L-CYSTEINE N_α-Boc-S-trityl-L-cysteine N-T-boc-S-trityl-L-cysteine crystalline NALPHA-tert-Butoxycarbonyl-S-trityl-L-cysteine (Tert-Butoxy)Carbonyl Cys(Trt)-OH (Non-Animal Origin) Boc-Cys(Trt)-NH2(non-animal) Boc-Cys(Trt)-OH(non-animal) (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-tritylsulfanylpropanoicaci N-Boc-S-Trityl-L-cysteine USP/EP/BP N-BOC-S-trityl-cysteine N-tert butyloxycarbonyl-S-triphenylmethyl-L-cysteine N-Boc-S-trityl-L-cysteine,97% Nα-(tert-Butoxycarbonyl)-S-(trityl)-L-cysteine Fmoc-L-Cysteine(Trt)-OH BOC-L-CYS(TRT)-OH Boc-Cys(Trt) N-(TERT-BUTOXYCARBONYL)-S-TRITYL-L-CYSTEINE 21947-98-8 C6H53CSCH2CHNHCO2CCH33CO2H C27H29NO4S Specialty Synthesis Peptide Synthesis Cysteine/Cystine Amino Acid Derivatives Cysteine [Cys, C] Boc-Amino Acids and Derivative Boc-Amino acid series Amino Acid Derivatives Amino Acids