Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1-Lauryl-2-pyrrolidone

1-Lauryl-2-pyrrolidone

1-Lauryl-2-pyrrolidone Structure
1-Lauryl-2-pyrrolidone structure
CAS No.
2687-96-9
Chemical Name:
1-Lauryl-2-pyrrolidone
Synonyms
LAURYL PYRROLIDONE;1-DODECYL-2-PYRROLIDINONE;N-DODECYL-2-PYRROLIDONE;Creastar Au-Ex;Sulfadone LP-300;N-Laurylpyrrolidone;N-DODECYLPYRROLIDONE;1-dodecylpyrrolidone;1-Lauryl-2-pyrrolido;n-dodecylpyrrolidinone
CBNumber:
CB4358536
Molecular Formula:
C16H31NO
Molecular Weight:
253.42
MDL Number:
MFCD00075066
MOL File:
2687-96-9.mol
MSDS File:
SDS
Last updated:2026-05-28 06:00:32
Request For Quotation

1-Lauryl-2-pyrrolidone Properties

Melting point 4°C
Boiling point 202-205 °C11 mm Hg(lit.)
Density 0.89 g/mL at 25 °C(lit.)
vapor pressure 0.002Pa at 25℃
refractive index n20/D 1.466(lit.)
Flash point >230 °F
storage temp. Sealed in dry,Room Temperature
form viscous liquid
pka -0.43±0.20(Predicted)
Appearance Colorless to light yellow Liquid
Water Solubility 51.7mg/L at 20℃
Cosmetics Ingredients Functions CLEANSING
SURFACTANT - CLEANSING
HAIR CONDITIONING
InChI 1S/C16H31NO/c1-2-3-4-5-6-7-8-9-10-11-14-17-15-12-13-16(17)18/h2-15H2,1H3
InChIKey NJPQAIBZIHNJDO-UHFFFAOYSA-N
SMILES CCCCCCCCCCCCN1CCCC1=O
LogP 4.03 at 21℃
CAS DataBase Reference 2687-96-9(CAS DataBase Reference)
EWG's Food Scores 1-2
FDA UNII 3P14VW8FNY
EPA Substance Registry System N-Lauryl-2-pyrrolidone (2687-96-9)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)Environment (GHS09)
GHS05,GHS07,GHS09
Signal word  Danger
Hazard statements  H314-H317-H410
Precautionary statements  P261-P272-P273-P280-P303+P361+P353-P305+P351+P338
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  C,N
Risk Statements  34-43-50/53
Safety Statements  26-36/37/39-45-60-61
RIDADR  UN 3267 8/PG 3
WGK Germany  2
RTECS  UY5768000
TSCA  TSCA listed
HazardClass  8
PackingGroup  III
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Aquatic Acute 1
Aquatic Chronic 1
Skin Corr. 1B
Skin Sens. 1
REACH Registrations Active

1-Lauryl-2-pyrrolidone price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 335673 1-Dodecyl-2-pyrrolidinone 99% 2687-96-9 250ml $106 2026-04-30 Buy
AK Scientific J60101 1-Dodecyl-2-pyrrolidinone 98% 2687-96-9 5mL $12 2026-06-04 Buy
AK Scientific J60101 1-Dodecyl-2-pyrrolidinone 98% 2687-96-9 25mL $22 2026-06-04 Buy
AK Scientific J60101 1-Dodecyl-2-pyrrolidinone 98% 2687-96-9 100mL $41 2026-06-04 Buy
AK Scientific E573 1-Dodecyl-2-pyrrolidinone 99%(GC) 2687-96-9 5mL $16 2026-06-04 Buy
Product number Packaging Price Buy
335673 250ml $106 Buy
J60101 5mL $12 Buy
J60101 25mL $22 Buy
J60101 100mL $41 Buy
E573 5mL $16 Buy

1-Lauryl-2-pyrrolidone Chemical Properties,Uses,Production

Chemical Properties

Colorless transparent liquid

Uses

1-Dodecyl-2-pyrrolidinone was used in the preparation of few-layered flakes of molybdenum disulfide (MoS2) via liquid phase exfoliation of bulk MoS2 powder.

Definition

ChEBI: 1-dodecylpyrrolidin-2-one is pyrrolidin-2-one substituted at nitrogen by an n-dodecyl group. It has a role as an epitope.

General Description

1-Dodecyl-2-pyrrolidinone is an N-alkyl lactam and its reduction with LiH3BNMe2 to the corresponding amine has been reported. It is a potential melatonin-specific chemical penetration enhancer.

Flammability and Explosibility

Non flammable

Synthesis

2-Pyrrolidinone

616-45-5

1-Bromododecane

143-15-7

1-Lauryl-2-pyrrolidone

2687-96-9

Step A: Tetrabutylammonium bromide (950 mg, 3 mmol, 0.05 eq.) and powdered potassium hydroxide (23.1 g, 411 mmol, 7 eq.) were sequentially added to a toluene (60 mL) solution of 2-pyrrolidone (5.00 g, 58.8 mmol) under stirring conditions. Subsequently, a toluene solution of bromododecane (18.5 mL, 76.4 mmol, 1.3 eq.) was added to the mixture. The reaction mixture was heated to 50 °C and stirred at this temperature overnight. The progress of the reaction was monitored by thin layer chromatography (TLC) using a solvent mixture of ethyl acetate and cyclohexane (4:1, v/v) as the unfolding agent and phosphomolybdic acid as the color developer until the complete disappearance of 2-pyrrolidone. After completion of the reaction, the mixture was cooled to room temperature, 60 mL of water was added and stirring was continued for 15 min. The aqueous and organic phases were separated and the aqueous phase was extracted once with diethyl ether (60 mL). The organic phase was combined, dried with anhydrous sodium sulfate, filtered and concentrated. The product was purified by vacuum distillation (146 °C, 0.5 mbar) to afford N-dodecylpyrrolidin-2-one in 80% yield. The structure of the product was characterized by 1H NMR and 13C NMR: 1H NMR (400 MHz, CDCl3) δ (ppm): 0.88 (t, 3H, J = 7.0 Hz, CH3); 1.25-1.31 (m, 18H, CH2); 1.47-1.54 (m, 2H, Alk-CH2-CH2-N); 1.97- 2.05 (m, 2H, CO-CH2-CH2-CH2-N); 2.38 (t, 2H, J = 8.0 Hz, CO-CH2-CH2-CH2-N); 3.26 (t, 2H, J = 7.5 Hz, Alk-CH2-CH2-N); 3.37 (t, 2H, J = 7.0 Hz, CO-CH2-CH2-CH2- N).13C NMR (100 MHz, CDCl3) δ (ppm): 14.3 (CH3); 18.1 (CO-CH2-CH2-CH2-N); 22.9; 27.0 (CH2alk); 27.5 (Alk-CH2-CH2-N); 29.5; 29.7; 29.8; 29.9 (CH2alk); 31.3 (CO-CH2-CH2-CH2-N); 32.1 (CH2alk); 42.7 (Alk-CH2-CH2-N); 47.2 (CO-CH2-CH2-CH2-N); 174.9 (CO).

References

[1] Patent: US2015/133688, 2015, A1. Location in patent: Page/Page column

1-Lauryl-2-pyrrolidone Preparation Products And Raw materials

Raw materials

2-Pyrrolidinone 1-Bromododecane Tetrabutylammomium bromide Cyclohexane Toluene
Water Ethyl acetate

1of2

Preparation Products

1-Lauryl-2-pyrrolidone Suppliers

Global( 193)Suppliers
Supplier Tel Email Country ProdList Advantage
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
XiaoGan ShenYuan ChemPharm co,ltd 15527621225; 15527621225 1791901229@qq.com China 6746 52
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Syntechem Co.,Ltd info@syntechem.com China 12973 57
China Langchem Inc. 0086-21-58956006 China 7798 57
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14412 57
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 22497 55
Supplier Advantage
TAIYUAN RHF CO.,LTD. 56
Energy Chemical 61
Shanghai Hanhong Scientific Co.,Ltd. 64
XiaoGan ShenYuan ChemPharm co,ltd 52
Shandong Xiya Chemical Co., Ltd 57
Syntechem Co.,Ltd 57
China Langchem Inc. 57
Tianjin heowns Biochemical Technology Co., Ltd. 57
Shanghai T&W Pharmaceutical Co., Ltd. 58
9ding chemical ( Shanghai) Limited 55

View Lastest Price from 1-Lauryl-2-pyrrolidone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-dodecyl-2-pyrrolidinone pictures 2026-09-02 1-dodecyl-2-pyrrolidinone
2687-96-9
 20kg 99% 20 tons Qingdao RENAS Polymer Material Co., Ltd.
Lauryl Pyrrolidone pictures 2026-05-28 Lauryl Pyrrolidone
2687-96-9
 $8.70 10KG 99.5% min 10000kg Hebei Chuanghai Biotechnology Co,.LTD
1-Lauryl-2-pyrrolidone pictures 2026-03-20 1-Lauryl-2-pyrrolidone
2687-96-9
 $10.00 1kg 99% 100 mt Hebei Chuanghai Biotechnology Co., Ltd

1-Lauryl-2-pyrrolidone Spectrum

1-Lauryl-2-pyrrolidone(2687-96-9)1HNMR1-Lauryl-2-pyrrolidone(2687-96-9)IR1-Lauryl-2-pyrrolidone(2687-96-9)Raman

2687-96-9(1-Lauryl-2-pyrrolidone)Related Search:

Dodecylbenzenesulphonic acid 1,2-EPOXYTETRADECANE Ammonium lauryl sulfate 2-Pyrrolidinone N,N-Dimethyldodecylamine
1-Dodecanol DODECYLBENZENE N-Vinyl-2-pyrrolidone Polyvinylpyrrolidone Calcium dodecylbenzene sulfonate
4-Dodecylphenol mixture of isomers SODIUM LAURYL DIETHYLENEDIAMINOGLYCINATE METHYL-2-PYRROLIDONE Polyquaternium-11 1-Propylpyrrolidin-2-one
1-Ethyl-2-pyrrolidone N-Octyl pyrrolidone 1-Butylpyrrolidin-2-one

1of4

1-dodecyl-2-pyrrolidinon 1-Dodecyl-2-pyrrolidone N-DODECYLPYRROLIDONE N-DODECYL-2-PYRROLIDONE 1-Lauryl-2-pyrrolidone N-Laurylpyrrolidone 2-Pyrrolidinone, 1-dodecyl- 1-dodecylpyrrolidone N-TETRADECYL-2-PYRROLIDONE n-dodecylpyrrolidinone N-DODECYLPYRROLIDONE OR 1-DODECYLPYRROLIDONE N-Lauryl-2-pyrrolidone N-dodecy1-2-prrolidone 1-Dodecylpyrrolidin-2-one Sulfadone LP-300 1-Lauryl-2-pyrrolido N-(n-dodecyl) Pyrrolidinone N-Dodecyl-2-Pyrrolidinone Creastar Au-Ex 2687-96-9 1-Lauryl-2-pyrrolidone 1-n-Dodecyl-2-pyrrolidone 1-DODECYL-2-PYRROLIDINONE LAURYL PYRROLIDONE 2687-96-9 2687-96-4 Building Blocks Heterocyclic Building Blocks Pyrrolidines Building Blocks Heterocyclic Building Blocks Pyrrolidines